Mestrado em Ciências da Saúde (FM)
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Item type: Item , Avaliação do programa de formação no cuidado às pessoas com doenças crônicas não transmissíveis na atenção primária à saúde do estado de Goiás(Universidade Federal de Goiás, 2024-12-17) Dias, Iohanna Maria Guimarães; Santos, Patricia Tavares dos; http://lattes.cnpq.br/8052298165888796; Rocha, Bárbara Souza; http://lattes.cnpq.br/8046110202782418; Rocha, Bárbara Souza; Pereira, Edna Regina Silva; Nunes, Cynthia Assis de BarrosResumoItem type: Item , Avaliação da funcionalidade e incapacidade do indivíduo pós bloqueio anestésico na capsulite adesiva secundária(Universidade Federal de Goiás, 2021-09-16) Nunes, Sara Ribeiro; Fernandes, Marcos Rassi; http://lattes.cnpq.br/3918453247388300; Fernandes, Marcos Rassi; http://lattes.cnpq.br/3918453247388300; Ribeiro, Luciana Castaneda; http://lattes.cnpq.br/4803387502034526; Assis, Thaís Rocha; http://lattes.cnpq.br/2272528203008924Embargada.Item type: Item , Associação de variantes genéticas em LXRA e LXRB com fenótipos de Esclerose Lateral Amiotrófica(Universidade Federal de Goiás, 2025-07-08) Bittar, Jacqueline Soares Barros; Reis, Angela Adamski da Silva; Santos, Rodrigo da Silva; http://lattes.cnpq.br/4806187026900959; Santos, Rodrigo da Silva; Barbosa, Mônica Santiago; Franchi, Leonardo PereiraAmyotrophic Lateral Sclerosis (ALS) is a chronic, fatal neurodegenerative disease that affects motor neurons and leads to premature death. In most cases, its etiology remains unknown. The LXRA and LXRB genes encode the LXR-alpha and LXR-beta proteins, respectively. These nuclear receptors function as key transcription factors involved in lipid metabolism and exert neuroprotective and anti-inflammatory effects in the central nervous system. Objective: This study investigated the association between the genetic variants rs2279238 (LXRA) and rs2695121 (LXRB) and ALS phenotypes. Materials and methods: This is a casecontrol study conducted with 115 patients diagnosed with amyotrophic lateral sclerosis (ALS) and 115 control participants without neurodegenerative diseases, matched by sex and age, from the Central-West region of Brazil, between 2017 and 2024. Single nucleotide variants (SNVs) were identified using real-time polymerase chain reaction (qPCR). Results: The LXRA variant rs2279238 showed similar genotypic frequencies in both the case and control groups, indicating no significant association with ALS risk. However, the LXRB variant rs2695121 showed a strong association with ALS phenotypes. In the codominant inheritance model, individuals with the C/T genotype had a 2.5-fold increased risk (p = 0.002), and those with the T/T genotype had a 3.7- fold increased risk (p = 0.005), compared to the C/C wild type. The dominant model (C/T + T/T vs. C/C) indicated a 2.7-fold higher risk (p < 0.001). In the overdominant model (C/T vs. C/C + T/T), heterozygotes had an odds ratio of 1.81 fold increased risk (p = 0.025), suggesting an independent association with disease risk. When analyzing gene-gene interactions, individuals with the heterozygous rs2279238 (LXRA) variant combined with the wild-type rs2695121 (LXRB) genotype exhibited a reduced risk of ALS, with a statistically significant association (OR = 0.31; p = 0.049). Discussion: These findings suggest an association between the LXRB gene and ALS susceptibility and highlight the potential modulatory role of LXRA in reducing risk when in heterozygous form. Further research is warranted to clarify the underlying mechanisms and to explore the role of LXR proteins in ALS pathophysiology. Conclusion: The rs2695121 variant in the LXRB gene is associated with ALS phenotypes. While the rs2279238 variant in LXRA was not directly associated with the disease, its presence in heterozygous form may confer a protective effect when combined with the wild-type LXRB genotype.Item type: Item , Tendência temporal das Práticas Integrativas e Complementares no estado de Goiás e suas macrorregiões de saúde: avaliação do período de 2014 a 2022(Universidade Federal de Goiás, 2025-04-29) Mariosa, Natália De Filippo; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225; Oliveira, Michele Dias da Silva; http://lattes.cnpq.br/2294835800087293; Zapata, Marco Tulio Antonio Garcia; http://lattes.cnpq.br/3672512339058369EmbargadoItem type: Item , Análise da síndrome de burnout em mulheres mães trabalhadoras da área da saúde(Universidade Federal de Goiás, 2025-07-19) Damaceno, Nara Siqueira; Marciano, Rafaela Paula; http://lattes.cnpq.br/2719045150171823; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; Porto, Maria Laura de Almeida; Montalvão, Luciano AlvarengaEmbargadoItem type: Item , Comparação do desempenho acadêmico e percepção dos universitários na disciplina de anatomia humana nos cursos da saúde por meio do ensino remoto e o ensino presencial(Universidade Federal de Goiás, 2025-04-11) Barradas, Camila Araújo; Rebelo, Ana Cristina Silva; http://lattes.cnpq.br/1542664015677213; Rebelo, Ana Cristina Silva; http://lattes.cnpq.br/1542664015677213; Freitas Junior, Ruffo de; http://lattes.cnpq.br/7343840830786566; Silva, Carolina Ribeiro e; http://lattes.cnpq.br/5491812153712081Human anatomy is fundamental to the training of all health professionals. However, the COVID19 (coronavirus disease) pandemic, which began in March 2020, has brought major challenges, such as social isolation and the temporary suspension of teaching activities. Faced with this scenario, remote teaching has allowed the educational process to continue. From this perspective, the need arose to understand whether remote teaching influences academic performance. Thus, the aim of this study was to compare the academic performance of students through remote teaching and face-to-face teaching, as well as to analyze the students' perception of the subject, considering the teaching performance and a student selfassessment. Final grades and pass/fail results were used to analyze academic performance. For the students' perception, the Institutional Assessment Forms were analyzed, which assess both the teacher's performance and the students' personal development. The study involved students from the Biomedicine, Biotechnology, Biological Sciences, Physical Education, Nursing, Pharmacy, Physiotherapy, Nutrition and Dentistry courses, the majority of whom were female (62.8%); 37.2% were male; 95.8% were single, 1.9% were married, 1.5% did not provide information and 0.7% were divorced, widowed or consensually separated. The results indicated that statistically there was no significant difference in academic performance between the periods analyzed, the average final grade of the students via remote teaching was 7.54 (± 2.81), while those in face-to-face teaching the average dropped to 6.77 (± 2.22). With regard to the situation on the course, during remote teaching the pass rate was 84.6% and the fail rate was 15.45%; during face-to-face teaching the pass rate was 83.5% and the fail rate was 16.5% (p = 0.743). With regard to academic perception, in the dimension of Teacher Evaluation, remote teaching generated an average score of 9.47 (±0.62) and face-to-face teaching generated an average score of 9.33 (±0.74) with p=0.18. And in the dimension of student selfassessment, remote teaching generated an average score of 9.46(±0.46) and face-to-face teaching generated an average score of 9.56(±0.51) with p=0.8. Based on the evidence found in this study, it can be concluded that there was a maintenance of academic performance and a positive perception of remote teaching compared to face-to-face teaching. The results suggest that the use of technology and the adaptation of teaching methods can be effective in higher education even in times of crisis.Item type: Item , Associação entre demências e comprometimento cognitivo leve com deficiências visuais e doenças oculares em adultos com 50 anos ou mais: evidências do Estudo Longitudinal da Saúde dos Idosos Brasileiros (ELSI-Brasil)(Universidade Federal de Goiás, 2025-05-26) Hadler, Bruna Costa Monteiro; Silveira, Erika Aparecida da; http://lattes.cnpq.br/3801865783333828; Silveira, Erika Aparecida da; http://lattes.cnpq.br/3801865783333828; Alves, Gilberto Sousa; http://lattes.cnpq.br/3199266195555914; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225EmbargadoItem type: Item , Lactato sérico em recém-nascidos asfíxicos: uma coorte histórica(Universidade Federal de Goiás, 2019-09-09) Magalhães, Danilo de Freitas; Peixoto, Fernanda Aparecida de Oliveira; http://lattes.cnpq.br/5866594930986112; Costa, Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Costa, Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Brito, Rosângela Maria de Moura; http://lattes.cnpq.br/2196759955450070; Fortes, Patrícia Marques; http://lattes.cnpq.br/9816674348461951Background: Perinatal asphyxia (AP) is the leading cause of death in the neonatal period and there is no consensus in the literature on its adequate diagnosis. Serum lactate is a promising laboratory marker and has been scarcely studied in the literature. Objective: To correlate serum lactate level with the diagnosis of perinatal asphyxia. Methods: This is a descriptive study of a historical cohort performed through the analysis of medical records of newborns with gestational age greater than or equal to 34 weeks, who had lactate levels in the first 24 hours of life and were admitted to the neonatal intensive care unit of the Clinics of the Federal University of Goiás from 2015 to 2018. We analyzed the serum lactate level with one hour of life and 24 hours of life. Statistical analysis was performed using SPSS v.20 software (SPSS Inc .; Chicago, IL). Results: The final sample consisted of 92 children, with a mean gestational age of 36.5 weeks, weight average of 2,746.7 grams, 52.2% male and 47.8% female. In children diagnosed with perinatal asphyxia, the serum lactate value in the first hour of life was significantly higher (p = 0.003) compared to the non-asphyxiated group. At 24 hours of life there was a relative decrease in lactate value, but still remained higher in newborns with perinatal asphyxia. Conclusions: There was a strong correlation between increased serum lactate in the first hours of life and the diagnosis of perinatal asphyxia.Item type: Item , Cinesioterapia e qualidade de vida após cirurgia de câncer de mama: uma revisão sistemática com metanálise(Universidade Federal de Goiás, 2024-08-01) Ribeiro, Matheus Gonçalves; Soares, Leonardo Ribeiro; http://lattes.cnpq.br/1610585108528260; Soares, Leonardo Ribeiro; http://lattes.cnpq.br/1610585108528260; Lemos, Nayara Alves de Freitas; http://lattes.cnpq.br/5074078922336323; Rahal, Rosemar Macedo Sousa; http://lattes.cnpq.br/1322145394447454EmbargadoItem type: Item , Relação da dose resposta do exercício físico aeróbio sobre os sintomas de ansiedade estado de adultos jovens: um ensaio clínico randomizado e cruzado(Universidade Federal de Goiás, 2025-03-25) Oliveira, Vinnycius Nunes de; Lira, Claudio Andre Barbosa de; http://lattes.cnpq.br/3289964716112944; Lira, Claudio Andre Barbosa de; Schuch, Felipe Barreto; Silva, Sergio Gomes daAnxiety can be a normal emotion or become pathological, characterized by excessive worry, anticipatory distress, and fear. In the latter case, anxiety symptoms can interfere with quality of life, particularly in terms of interpersonal relationships and self-fulfillment. The lifetime risk of developing an anxiety disorder exceeds 25%, making anxiety disorders one of the most prevalent psychiatric conditions and a leading cause of years of life lost due to disability or premature death worldwide. Of particular interest to the present study, aerobic exercise has been identified as an effective non-pharmacological tool for preventing and treating anxiety symptoms. Moreover, most studies evaluating the acute effect of aerobic exercise on anxiety symptoms have employed a variety of intensities, with no clear consensus on the optimal intensity for managing state anxiety symptoms. One of the factors influencing studies on the acute effects of aerobic exercise on state anxiety symptoms is the floor effect, where pre-exercise state anxiety symptoms are classified as mild. To address this, previous investigations have used methods to experimentally increase state anxiety symptoms. The advantage of this approach is that it allows for accuracy control of the intensity and duration of the anxiogenic stimulus. Objective: To investigate the dose-response relationship of acute aerobic exercise performed on a treadmill at different domains intensity (light, moderate, and vigorous) on state anxiety symptoms in healthy young individuals of both sexes, who were previously exposed to anxiogenic stimuli. Methods: This was a randomized crossover clinical trial. The sample consisted of 77 participants (39 women) with a median age of 25.53 years. The study was divided into five stages, conducted on separate days (48-96h). The first stage included a detailed explanation of the research, signing of the informed consent form, general anamnesis, assessment of trait anxiety symptoms, and cardiorespiratory fitness evaluation. The subsequent stages consisted of aerobic exercise sessions at light, moderate, and vigorous intensities on a treadmill, as well as a control session involving rest without exercise. The order of sessions was determined through counterbalanced randomization. The aerobic exercise sessions included a 5-minute warm-up at 3.8 km/h, a 30-minute main phase, and a cool-down phase with the same speed and Abstract xvi duration as the warm-up, totaling 40 minutes. The control session, consisting of rest without exercise, also lasted 40 minutes. The prescription of aerobic exercise was based on the percentage of each participant’s maximum heart rate achieved during the cardiorespiratory fitness assessment. State anxiety symptoms were assessed before exposure to unpleasant images, after exposure to unpleasant images, and after both the aerobic exercise and control sessions using the State-Trait Anxiety Inventory. For statistical analysis, a linear mixed model was used to compare the acute effects of treadmill aerobic exercise performed at different domains intensity on state anxiety symptoms. Results: Statistical analysis provided strong evidence of an interaction between time and session (F = 4.812; p-value < 0.001; ηp² = 0.051, small effect size) on participants’ state anxiety symptoms. Holm’s post hoc test revealed moderate evidence that light-intensity aerobic exercise (z = 3.187; p-value = 0.010) was superior to the control session, very strong evidence that moderateintensity aerobic exercise (z = 4.678; p-value < 0.001) was superior to the control session, and strong evidence that vigorous-intensity aerobic exercise (z = 3.470; pvalue = 0.004) was superior to the control session in reducing state anxiety symptoms induced by unpleasant images. Additionally, Holm’s post hoc test showed no differences between the three aerobic exercise intensities in reducing state anxiety symptoms. Statistical analysis also revealed no differences in the anxiolytic response elicited by different aerobic exercise intensities between sexes. Conclusions: Treadmill aerobic exercise sessions at light, moderate, and vigorous intensities were effective in reducing state anxiety symptoms following exposure to unpleasant images compared to the control session, with no differences between intensities. This indicates that there was no dose-response relationship between aerobic exercise intensity and the reduction of state anxiety symptoms. Furthermore, this effect was consistent across both sexes. These findings highlight the role of treadmill aerobic exercise as a viable strategy for managing anxiety symptoms, regardless of sex or exercise intensity. Therefore, health professionals can advise young and healthy individuals to perform aerobic exercise on a treadmill without the need for advice on a specific intensity of physical exercise.Item type: Item , Hipertensão Arterial Avaliada no Sistemas Público e Privado de Saúde Brasileiro(Universidade Federal de Goiás, 2023-05-31) Amorim, Kécia Cristina Faria de Oliveira; Vitorino, Priscila Valverde de Oliveira; http://lattes.cnpq.br/1815619227221108; Sousa, Ana Luiza Lima; Barroso, Weimar Kunz Sebba; http://lattes.cnpq.br/6847019017274804; Jardim, Paulo César Veiga; Souza, Weimar Kunz Sebba Barroso de; Babkowski, Miguel CamafortArterial hypertension (AH) control rates in Brazil and Latin America are low, approximately 20%. This is a serious problem, as it is the risk factor that is the main cause of death worldwide. On the other hand, rates of 60,6% are found in patients with AH treated by cardiologists and in private service. Objective: To compare socio-demographic characteristics, body mass index (BMI), use of antihypertensive drugs (AH), blood pressure (BP) between patients with followed in public (SRPU) and private (SRPR) reference services; and their control rates an uncontrolled AH phenotype. Methodology: This is a national multicenter cross-sectional study that evaluated treated hypertensive patients followed up in two SRPUs and in two SRPR under the same coordination and conduct guidance. Gender, age, BMI, classes an the number of AH uses, and mean values of systolic (SBP) and diastolic (DBP) blood pressure by office measurement and HBPM were evaluated Uncontrolled AH phenotypes (uncontrolled white coat Hypertension, uncontrolled masked hypertension and uncontrolled Sustained Hypertension) and BP control rates were also evaluated. Descriptive statistics and Chi-square tests or unpaired t-test we used for comparisons. A significance level of p <0.05 was considered. Results: A total of 2.956 patients were evaluated, 60,5% of whom were followed up at the SRPR. There was a predominance of females (58,9%), more evident in the SRPU (65,7%) than in the SRPR(54,5%). Only 21,7% of the sample were eutrophic. The prevalence of obesity in the SRPU was 42% and of SRPR 34,4% higher in the SRPU (p<0.001) and of overweight in the SRPR 37,5% and in the SRPR 43%; higher in the SRPR (p< 0.001);. The mean number of antihypertensive drugs used was 2.01.3 for the total sample, being 1.40.7 for SRPR and 2.91.5 for SRPU (p<0.001).Mean SBP and DBP values were higher in the SRPU (134 20.8 and 82 13.0). Uncontrolled AH rates were 67,8% in SRPU and 47,6% SRPR (p<0.001) by office measurement and 60,4% in SRPU and 35,3% en SRPR (p<0.001) by HBPM. Conclusions: Hypertensive patients are mostly female, have a higher prevalence of obesity in the SRPU and use a greater number of AH drugs, maintaining higher mean values of SBP and DBP, either in the office measurement or by HBPM, than in the SRPR. BP control rates are worse in SRPU, on average 15.3 mmhg and 12,1 mmhg in systolic and diastolic pressure respectively higher than in SRPR by office measurement. Higher prevalence of uncontrolled sustained hypertension (HSNC) and uncontrolled white coat (HABNC) in the SRPU were found.Item type: Item , Detecção das desordens potencialmente malignas de lábio e cavidade oral (DBPM): modelo de informação para a atenção primária em saúde(Universidade Federal de Goiás, 2024-07-19) Castilho, Suse Barbosa; Zara, Ana Laura de Sene Amâncio; http://lattes.cnpq.br/3893158152564208; Ribeiro-Rotta, Rejane Faria; http://lattes.cnpq.br/9466795079344876; Ribeiro-Rotta, Rejane Faria; Meurer , Maria Inês; Zinader, Juliana Pereira de Souza; Lucena, Fábio Nogueira de; Amaral, Rita GoretiFor the effectiveness of early detection of oral cancer (OC), greater investments in public policies to strengthen Primary Health Care (PHC) actions are necessary, including the use of information and communication technologies to support clinical decision-making. Information models (IM) can guide clinical assessment in health as well as the development of interoperable electronic health information systems, particularly in PHC, where they can contribute to more accurate referrals to other levels of health care. Objective: To propose an IM for the detection of potentially malignant oral disorders (PMOD) in PHC. Method: This is a qualitative study with a descriptive approach, using action research, associated with the Delphi Method. The study was organized into three stages: 1) identification of the minimum set of clinical criteria (MSCC) to support the differential diagnosis of PMOD; 2) validation of the MSCC and establishment of a Delphi Panel; 3) structuring of the IM. Results: A preliminary version of the CMCC was prepared by a specialist, submitted to pre-testing in the format of an electronic questionnaire on the REDCapⓇ Platform, generating a final version that was submitted to validation by the Delphi method, by 21 panelists (specialist dentists with experience in the diagnosis of PMDD). A total of 90% (n = 19/21) of the panelists responded to the first round and 86% (n = 18/21) responded to the second. All changes suggested in each round were analyzed, considering the Content Validity Index (CVI) ≥ 0.83. The Delphi Panel was completed in two rounds. The validated version of the CMCC resulted in a set of 30 questions, distributed in seven sections. From this CMCC, an MI was proposed in the format of a table, containing 80 data elements in the rows, structured in seven sections: anamnesis/sociodemographic information (n=9); anamnesis/history and lifestyle habits (n=16); clinical presentation of the lesion (n=18); clinical diagnosis (n=2); histopathological diagnosis (n=2); clinical conduct (n=1) and differential diagnosis (n=34). In the columns, the elements are arranged according to level, occurrence, description, type of data and standard codes. Conclusions: The MSCC developed and validated for the differential clinical diagnosis of PMOD represents an important step in obtaining the fundamental data elements for the definition of the IM and for the construction of an interoperable Computational Model for PHC. This could contribute to advances in the digital transformation of health within the context of oral health, with a potential impact on the quality of health care.Item type: Item , Avaliação das alterações da microvasculatura fovel na angiografia por tomografia de coerência óptica em olhos de pacientes com diabete tipo 2, diagnosticados há mais de 5 ano, sem sinais clínicos de retinopatia diabética, versus paciente sem diabetes(Universidade Federal de Goiás, 2024-04-02) Pires, Alexandre Caiado Ferreira; Isaac, David Leonardo Cruvinel; http://lattes.cnpq.br/5474072354473614; David Leonardo Cruvinel; Isaac, David Leonardo Cruvinel; Silva, Leopoldo Magacho dos Santos; Taleb, Alexandre ChaterEmbargada.Item type: Item , Anfotericina B no manejo terapêutico das infecções fúngicas invasivas: revisão sistemática da literatura com metanálise(Universidade Federal de Goiás, 2023-09-28) Abrão, Mirela Pereira Lima; Soares, Renata de Bastos Ascenço; http://lattes.cnpq.br/2129359947528992; Garcia Zapata, Marco Tulio Antonio; http://lattes.cnpq.br/3672512339058369; Garcia Zapata, Marco Tulio Antonio; Barbosa, Maria Alves; Santos, Sônia de Fátima OliveiraEmbargadoItem type: Item , Monitoramento de tempo e conscientização no uso de smartphones: análise e comparação do efeito de intervenções na redução do tempo de uso(Universidade Federal de Goiás, 2025-03-01) Noronha Júnior, Sérgio Andrade; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; Alves, Rosane Ribeiro Figueiredo; Sousa, Juarez Antonio deEmbargado.Item type: Item , Avaliação das Funções Cognitivas dos pacientes com Lúpus Eritematoso Sistêmico(Universidade Federal de Goiás, 2022-10-06) Vieira, Juliana Rosa Pires; Fernandes, Marcos Rassi; http://lattes.cnpq.br/391845324738830; Fernandes, Marcos Rassi; Paiva, Yara Bezerra de; Dias, Danilo RochaIntroduction: Neurocognitive changes may hinder the autonomy and independence of patients diagnosed with Systemic Lupus Erythematosus (SLE), being considered as one of the main negative outcomes. Objectives: To evaluate the cognitive functions of patients diagnosed with active SLE and in remission, at the Rheumatology Outpatient Clinic of the Hospital das Clínicas, School of Medicine, Universidade Federal de Goiás. Methodology: This was a cross-sectional study, non-probabilistic sample and consecutive type. Mini Mental State Examination (MMSE), Five Digits Test (FDT) and Rey's Complex Figures (FCRey) were used in 83 patients, in the period from November 2021 to May 2022. Patients with depressive disorders and users of alcohol and other drugs were excluded. Results: In the assessed cognitive functions - attention, memory, language and executive functions - showed mild impairments, corroborating with previous studies. When comparing groups of patients with active SLE and in remission there was no significant difference (p>0.005) in relation to cognitive performance. Conclusion: In this sense, cognitive dysfunctions were present both in patients with active SLE and in remission, the results showed mild cognitive impairment in patients diagnosed with SLE.Item type: Item , Análise Clínica, Histopatológica E Do Perfil Inflamatório De Pacientes Portadores De Rinossinusite Crônica Com Polipose Nasal Em Um Hospital Universitário Terciário Do Centro-Oeste Do Brasil(Universidade Federal de Goiás, 2024-01-25) Rodrigues, Stela Oliveira; Avelino, Melissa Ameloti Gomes; http://lattes.cnpq.br/0519039948275501; Avelino, Melissa Ameloti Gomes; Lima, Wilma Terezinha Anselmo; Nakanishi, MárcioIntroduction: Chronic rhinosinusitis (CRS) is a disease with several clinical manifestations and endotypic characterization is widely studied for better therapeutic planning. The understanding of the profile of service patients is essential for better management. We aimed to elucidate the clinical and histopathological profile of patients with CRS with nasal polyps (CRSwNP) followed up at a tertiary hospital in the Brazilian Midwest, classifying them according to the predominance of inflammatory response. Methods: Patients with CRSwNP at the Hospital das Clínicas of the Federal University of Goiás were analyzed, trough the application of tomographic and endoscopic scores, clinical control of the disease, in addition to performing prick-test, biopsy of polyps (for histopathological analysis) and collection of epidemiological data. Furthermore, data from literature about the characteristics of the eosinophilic inflammatory response (type 2 pattern) were collected. Results: In descriptive analysis, a predominance of eosinophilic infiltration was observed in middle-aged patientes, with a majority of males, with comorbidities of asthma, allergic rhinitis and atopic dermatitis. There were no significant correlations between eosinophilia and the other data analyzed for each patient. In our systematic review, the main cytokines involved in the type 2 responde were highlighted. Conclusion: In the epidemiological evaluation of patients with CRS at the Hospital das Clínicas, we found a higher prevalence of eosinophilic infiltration, without significant correlations with other epidemiological data, similar to those found in the literature. The cytokines most involved in the type 2 response pattern in nasal polyposis are interleukin (IL)-4, IL-5 and IL-13.Item type: Item , Osteossarcopenia em idosos: prevalências, fatores associados e efetividade de intervenções com exercício físico(Universidade Federal de Goiás, 2021-10-04) Souza, Guilherme Vinícius Elias; Noll, Matias; http://lattes.cnpq.br/3709020347400351; Silveira, Erika Aparecida da; http://lattes.cnpq.br/3801865783333828; Silveira, Erika Aparecida da; Vieira, Carlos Alexandre; Gadelha, André BonadiasEmbargadoItem type: Item , Programa Nacional para Otimizar a detecção de Fibrilação Atrial paroxística RITMO PROTOCOL(Universidade Federal de Goiás, 2024-11-07) Andrade, Rodrigo Paashaus de; Souza, Weimar Kunz Sebba Barroso de; Souza, Ana Luiza Lima; http://lattes.cnpq.br/6578713509935374; Souza, Ana luiza Lima; Miranda, Roberto Dischinger; Vitorino, Priscila Valverde de OliveiraEmbargado.Item type: Item , Sistema renina-angiotensina-aldosterona: Existe associação genética entre o polimorfismo I/D da enzima ECA com a esclerose lateral amiotrófica?(Universidade Federal de Goiás, 2024-12-05) Bento, Dhiogo da Cruz Pereira; Reis, Angela Adamski da Silva; Santos, Rodrigo da Silva; http://lattes.cnpq.br/4806187026900959; Santos, Rodrigo da Silva; Silveira, Luciana Carvalho; Jesuíno, Rosália Santos Amorim; ReisEmbargado.