Mestrado em Ciências da Saúde (FM)
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Item type: Item , Perfil dos pacientes submetidos a aplicação de injeção intravítrea de anti-VEGF no Centro de Referência em Oftalmologia do Hospital das Clínicas da Universidade Federal de Goiás entre novembro de 2017 e janeiro de 2021(Universidade Federal de Goiás, 2025-09-24) Ximenes, Rodrigo Álvares Salum; Isaac, David Leonardo Cruvinel; http://lattes.cnpq.br/5474072354473614; Isaac, David Leonardo Cruvinel; Ávila, Marcos Pereira de; Mendonça, Luísa Salles de MouraEmbargadoItem type: Item , Mini-implante versus implante convencional para overdenture maxilar: Avaliação das taxas de indicação a partir do planejamento cirúrgico digital(Universidade Federal de Goiás, 2025-11-21) Adorno, Marcelo Rocha; Leles, Cláudio Rodrigues; http://lattes.cnpq.br/6740286066154410; Leles, Cláudio Rodrigues; http://lattes.cnpq.br/6740286066154410; Costa, Nádia do Lago; http://lattes.cnpq.br/9120865567187887; Silva, Fernanda Paula Yamamoto; http://lattes.cnpq.br/0511229119340734ResumoItem type: Item , Perfil epidemiológico de retinopatia da prematuridade Em pré-termos assistidos em um hospital terciário do centro-oeste: Estudo trasnversal(Universidade Federal de Goiás, 2025-11-18) Queiroz, Victória Coelho Jácome; Gomes, Maria Bárbara Franco; http://lattes.cnpq.br/7394332970179505; Costa, Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Costa, Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Vilela , Maria Ivone Oliveira Pinto; Fortes, Patrícia Marques; http://lattes.cnpq.br/9816674348461951ResumoItem type: Item , Doença de Chagas: A Importância do Histórico Familiar em Indivíduos Atendidos em Hospital Universitário no Estado de Goiás(Universidade Federal de Goiás, 2025-11-27) Rodrigues, Ernilva dos Santos; Ostermayer, Alejandro Luquetti; http://lattes.cnpq.br/1233757220404080; Oliveira, Enio Chaves de; http://lattes.cnpq.br/7046861881778720; Oliveira, Enio Chaves de; http://lattes.cnpq.br/7046861881778720; Castro, Ana Maria de; http://lattes.cnpq.br/9232309971000621; Bafutto, Alexandre Augusto FerreiraResumoItem type: Item , Avaliação colônica por enema baritado de pacientes chagásicos com e sem constipação(Universidade Federal de Goiás, 2025-10-03) Bittar Neto, Jarbas Jabur; Oliveira, Ênio Chaves de; http://lattes.cnpq.br/7046861881778720; Oliveira, Ênio Chaves de; http://lattes.cnpq.br/7046861881778720; Bafutto, Mauro; http://lattes.cnpq.br/6075384881986001; Rezende Filho, Joffre; http://lattes.cnpq.br/4676204316384198Embargada.Item type: Item , Comparação de dois aparelhos de biometria óptica no cálculo da lente intraocular em pacientes com ceratocone(Universidade Federal de Goiás, 2024-08-29) Salgado, Larissa Fernanda Queiroz Elias; Fernandes, Marcos Rassi; http://lattes.cnpq.br/3918453247388300; Fernandes, Marcos Rassi; http://lattes.cnpq.br/3918453247388300; Mendonça, Luísa Salles de Moura; http://lattes.cnpq.br/2346628944052737; Stival, Larissa Rossana Souza; http://lattes.cnpq.br/6178756054679892The purposes of this study were to compare and correlate the biometric parameters obtained by the devices, IOLMaster 700 and Lenstar LS 900, in patients with keratoconus; and to verify which parameter interferes most in the calculation of the power of the intraocular lens (IOL) in these patients. Sixty eyes of patients aged 18 years or older with keratoconus were prospectively evaluated using corneal tomographic criteria, who had not undergone any previous corneal surgical procedure and without any corneal opacity, originating from the Ophthalmology Reference Center (CEROF) of the Federal University of Goiás (UFG) from April 2023 to August 2023. The following biometric data were compared between the devices: axial diameter (AL), flattest keratometry (K1), most curved keratometry (K2), corneal astigmatism (ASTIG), anterior chamber depth (ACD) and calculation of the intraocular lens (IOL) power. The comparison of means and agreement analysis between the devices was tested using the paired t-test and Pearson's correlation analysis, respectively. The correlation between IOL Master and Lenstar was positive, with r > 0.85 in all parameters evaluated. There was a statistically significant difference in the evaluation of the means between the biometric parameters evaluated (K1, K2, ASTIG, ACD and LIO) in the t-test with p<0.001, with no statistically significant difference in relation to the AL parameter. In the multiple linear regression analysis, K2 was the main factor responsible for the variation in LIO values between the biometers with t of 2.93 and p<0.001. It is concluded that there is a discrepancy between the parameters evaluated through the biometers in patients with keratoconus, with a consequent difference in the LIO power, which may result in future postoperative refractive error. Therefore, the IOL Master 700 and Lenstar LS900 devices are not coincident in these patientsItem type: Item , Análise da interface em diferentes sistemas de pinos de fibra de vidro e em técnicas de cimentação por meio de um novo software de tomografia computadorizada de feixe cônico(Universidade Federal de Goiás, 2022-06-28) Cruvinel Filho, Jorge Luiz de Oliveira; Rocha, Sicknan Soares da; http://lattes.cnpq.br/8256226109956656; Estrela, Carlos; http://lattes.cnpq.br/4939545848747102; Estrela, Carlos; Alencar, Ana Helena Gonçalves de; Paula, Juliê Marra deEmbargadoItem type: Item , Avaliação da esofagopatia chagásica por manometria de alta resolução de perfusão(Universidade Federal de Goiás, 2025-08-29) Silva, Talita Ramos De Alencar; Oliveira, Enio Chaves de; http://lattes.cnpq.br/7046861881778720; Rezende Filho, Joffre; http://lattes.cnpq.br/4676204316384198; Oliveira , Enio Chaves de; http://lattes.cnpq.br/7046861881778720; Bafutto , Mauro; http://lattes.cnpq.br/6075384881986001; Souza, Diogo Henrique Saliba deResumoItem type: Item , Avaliação das atividades toxicogenéticas e angiogênicas da lectina purificada de Canavalia maritima (ConM)(Universidade Federal de Goiás, 2025-08-22) Paiva, Felipe Eduardo Alves de; Teixeira, Claudener Souza; http://lattes.cnpq.br/0728801046272432; Cardoso, Clever Gomes; http://lattes.cnpq.br/9545455455623006; Cardoso, Clever Gomes; http://lattes.cnpq.br/9545455455623006; Franchi, Leonardo Pereira; http://lattes.cnpq.br/8068976548504815; Chen, Lee Chen; http://lattes.cnpq.br/4621907105842007Embargada.Item type: Item , Transtornos dissociativo e conversivo: aspectos psicopatológicos, comorbidades e fatores fisiopatogênicos(Universidade Federal de Goiás, 2024-06-11) Bannach, Mariana Lima Caetano; Caixeta, Leonardo Ferreira; http://lattes.cnpq.br/9536747113677509; Caixeta, Leonardo Ferreira; http://lattes.cnpq.br/9536747113677509; Almeida, Alexander Moreira; http://lattes.cnpq.br/9072644751174322; Vêncio, Sérgio Alberto Cunha; http://lattes.cnpq.br/8930226981827995Embargada.Item type: Item , Avaliação do programa de formação no cuidado às pessoas com doenças crônicas não transmissíveis na atenção primária à saúde do estado de Goiás(Universidade Federal de Goiás, 2024-12-17) Dias, Iohanna Maria Guimarães; Santos, Patricia Tavares dos; http://lattes.cnpq.br/8052298165888796; Rocha, Bárbara Souza; http://lattes.cnpq.br/8046110202782418; Rocha, Bárbara Souza; Pereira, Edna Regina Silva; Nunes, Cynthia Assis de BarrosResumoItem type: Item , Avaliação da funcionalidade e incapacidade do indivíduo pós bloqueio anestésico na capsulite adesiva secundária(Universidade Federal de Goiás, 2021-09-16) Nunes, Sara Ribeiro; Fernandes, Marcos Rassi; http://lattes.cnpq.br/3918453247388300; Fernandes, Marcos Rassi; http://lattes.cnpq.br/3918453247388300; Ribeiro, Luciana Castaneda; http://lattes.cnpq.br/4803387502034526; Assis, Thaís Rocha; http://lattes.cnpq.br/2272528203008924Embargada.Item type: Item , Associação de variantes genéticas em LXRA e LXRB com fenótipos de Esclerose Lateral Amiotrófica(Universidade Federal de Goiás, 2025-07-08) Bittar, Jacqueline Soares Barros; Reis, Angela Adamski da Silva; Santos, Rodrigo da Silva; http://lattes.cnpq.br/4806187026900959; Santos, Rodrigo da Silva; Barbosa, Mônica Santiago; Franchi, Leonardo PereiraAmyotrophic Lateral Sclerosis (ALS) is a chronic, fatal neurodegenerative disease that affects motor neurons and leads to premature death. In most cases, its etiology remains unknown. The LXRA and LXRB genes encode the LXR-alpha and LXR-beta proteins, respectively. These nuclear receptors function as key transcription factors involved in lipid metabolism and exert neuroprotective and anti-inflammatory effects in the central nervous system. Objective: This study investigated the association between the genetic variants rs2279238 (LXRA) and rs2695121 (LXRB) and ALS phenotypes. Materials and methods: This is a casecontrol study conducted with 115 patients diagnosed with amyotrophic lateral sclerosis (ALS) and 115 control participants without neurodegenerative diseases, matched by sex and age, from the Central-West region of Brazil, between 2017 and 2024. Single nucleotide variants (SNVs) were identified using real-time polymerase chain reaction (qPCR). Results: The LXRA variant rs2279238 showed similar genotypic frequencies in both the case and control groups, indicating no significant association with ALS risk. However, the LXRB variant rs2695121 showed a strong association with ALS phenotypes. In the codominant inheritance model, individuals with the C/T genotype had a 2.5-fold increased risk (p = 0.002), and those with the T/T genotype had a 3.7- fold increased risk (p = 0.005), compared to the C/C wild type. The dominant model (C/T + T/T vs. C/C) indicated a 2.7-fold higher risk (p < 0.001). In the overdominant model (C/T vs. C/C + T/T), heterozygotes had an odds ratio of 1.81 fold increased risk (p = 0.025), suggesting an independent association with disease risk. When analyzing gene-gene interactions, individuals with the heterozygous rs2279238 (LXRA) variant combined with the wild-type rs2695121 (LXRB) genotype exhibited a reduced risk of ALS, with a statistically significant association (OR = 0.31; p = 0.049). Discussion: These findings suggest an association between the LXRB gene and ALS susceptibility and highlight the potential modulatory role of LXRA in reducing risk when in heterozygous form. Further research is warranted to clarify the underlying mechanisms and to explore the role of LXR proteins in ALS pathophysiology. Conclusion: The rs2695121 variant in the LXRB gene is associated with ALS phenotypes. While the rs2279238 variant in LXRA was not directly associated with the disease, its presence in heterozygous form may confer a protective effect when combined with the wild-type LXRB genotype.Item type: Item , Tendência temporal das Práticas Integrativas e Complementares no estado de Goiás e suas macrorregiões de saúde: avaliação do período de 2014 a 2022(Universidade Federal de Goiás, 2025-04-29) Mariosa, Natália De Filippo; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225; Oliveira, Michele Dias da Silva; http://lattes.cnpq.br/2294835800087293; Zapata, Marco Tulio Antonio Garcia; http://lattes.cnpq.br/3672512339058369EmbargadoItem type: Item , Análise da síndrome de burnout em mulheres mães trabalhadoras da área da saúde(Universidade Federal de Goiás, 2025-07-19) Damaceno, Nara Siqueira; Marciano, Rafaela Paula; http://lattes.cnpq.br/2719045150171823; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; Porto, Maria Laura de Almeida; Montalvão, Luciano AlvarengaEmbargadoItem type: Item , Comparação do desempenho acadêmico e percepção dos universitários na disciplina de anatomia humana nos cursos da saúde por meio do ensino remoto e o ensino presencial(Universidade Federal de Goiás, 2025-04-11) Barradas, Camila Araújo; Rebelo, Ana Cristina Silva; http://lattes.cnpq.br/1542664015677213; Rebelo, Ana Cristina Silva; http://lattes.cnpq.br/1542664015677213; Freitas Junior, Ruffo de; http://lattes.cnpq.br/7343840830786566; Silva, Carolina Ribeiro e; http://lattes.cnpq.br/5491812153712081Human anatomy is fundamental to the training of all health professionals. However, the COVID19 (coronavirus disease) pandemic, which began in March 2020, has brought major challenges, such as social isolation and the temporary suspension of teaching activities. Faced with this scenario, remote teaching has allowed the educational process to continue. From this perspective, the need arose to understand whether remote teaching influences academic performance. Thus, the aim of this study was to compare the academic performance of students through remote teaching and face-to-face teaching, as well as to analyze the students' perception of the subject, considering the teaching performance and a student selfassessment. Final grades and pass/fail results were used to analyze academic performance. For the students' perception, the Institutional Assessment Forms were analyzed, which assess both the teacher's performance and the students' personal development. The study involved students from the Biomedicine, Biotechnology, Biological Sciences, Physical Education, Nursing, Pharmacy, Physiotherapy, Nutrition and Dentistry courses, the majority of whom were female (62.8%); 37.2% were male; 95.8% were single, 1.9% were married, 1.5% did not provide information and 0.7% were divorced, widowed or consensually separated. The results indicated that statistically there was no significant difference in academic performance between the periods analyzed, the average final grade of the students via remote teaching was 7.54 (± 2.81), while those in face-to-face teaching the average dropped to 6.77 (± 2.22). With regard to the situation on the course, during remote teaching the pass rate was 84.6% and the fail rate was 15.45%; during face-to-face teaching the pass rate was 83.5% and the fail rate was 16.5% (p = 0.743). With regard to academic perception, in the dimension of Teacher Evaluation, remote teaching generated an average score of 9.47 (±0.62) and face-to-face teaching generated an average score of 9.33 (±0.74) with p=0.18. And in the dimension of student selfassessment, remote teaching generated an average score of 9.46(±0.46) and face-to-face teaching generated an average score of 9.56(±0.51) with p=0.8. Based on the evidence found in this study, it can be concluded that there was a maintenance of academic performance and a positive perception of remote teaching compared to face-to-face teaching. The results suggest that the use of technology and the adaptation of teaching methods can be effective in higher education even in times of crisis.Item type: Item , Associação entre demências e comprometimento cognitivo leve com deficiências visuais e doenças oculares em adultos com 50 anos ou mais: evidências do Estudo Longitudinal da Saúde dos Idosos Brasileiros (ELSI-Brasil)(Universidade Federal de Goiás, 2025-05-26) Hadler, Bruna Costa Monteiro; Silveira, Erika Aparecida da; http://lattes.cnpq.br/3801865783333828; Silveira, Erika Aparecida da; http://lattes.cnpq.br/3801865783333828; Alves, Gilberto Sousa; http://lattes.cnpq.br/3199266195555914; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225EmbargadoItem type: Item , Lactato sérico em recém-nascidos asfíxicos: uma coorte histórica(Universidade Federal de Goiás, 2019-09-09) Magalhães, Danilo de Freitas; Peixoto, Fernanda Aparecida de Oliveira; http://lattes.cnpq.br/5866594930986112; Costa, Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Costa, Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Brito, Rosângela Maria de Moura; http://lattes.cnpq.br/2196759955450070; Fortes, Patrícia Marques; http://lattes.cnpq.br/9816674348461951Background: Perinatal asphyxia (AP) is the leading cause of death in the neonatal period and there is no consensus in the literature on its adequate diagnosis. Serum lactate is a promising laboratory marker and has been scarcely studied in the literature. Objective: To correlate serum lactate level with the diagnosis of perinatal asphyxia. Methods: This is a descriptive study of a historical cohort performed through the analysis of medical records of newborns with gestational age greater than or equal to 34 weeks, who had lactate levels in the first 24 hours of life and were admitted to the neonatal intensive care unit of the Clinics of the Federal University of Goiás from 2015 to 2018. We analyzed the serum lactate level with one hour of life and 24 hours of life. Statistical analysis was performed using SPSS v.20 software (SPSS Inc .; Chicago, IL). Results: The final sample consisted of 92 children, with a mean gestational age of 36.5 weeks, weight average of 2,746.7 grams, 52.2% male and 47.8% female. In children diagnosed with perinatal asphyxia, the serum lactate value in the first hour of life was significantly higher (p = 0.003) compared to the non-asphyxiated group. At 24 hours of life there was a relative decrease in lactate value, but still remained higher in newborns with perinatal asphyxia. Conclusions: There was a strong correlation between increased serum lactate in the first hours of life and the diagnosis of perinatal asphyxia.Item type: Item , Cinesioterapia e qualidade de vida após cirurgia de câncer de mama: uma revisão sistemática com metanálise(Universidade Federal de Goiás, 2024-08-01) Ribeiro, Matheus Gonçalves; Soares, Leonardo Ribeiro; http://lattes.cnpq.br/1610585108528260; Soares, Leonardo Ribeiro; http://lattes.cnpq.br/1610585108528260; Lemos, Nayara Alves de Freitas; http://lattes.cnpq.br/5074078922336323; Rahal, Rosemar Macedo Sousa; http://lattes.cnpq.br/1322145394447454EmbargadoItem type: Item , Relação da dose resposta do exercício físico aeróbio sobre os sintomas de ansiedade estado de adultos jovens: um ensaio clínico randomizado e cruzado(Universidade Federal de Goiás, 2025-03-25) Oliveira, Vinnycius Nunes de; Lira, Claudio Andre Barbosa de; http://lattes.cnpq.br/3289964716112944; Lira, Claudio Andre Barbosa de; Schuch, Felipe Barreto; Silva, Sergio Gomes daAnxiety can be a normal emotion or become pathological, characterized by excessive worry, anticipatory distress, and fear. In the latter case, anxiety symptoms can interfere with quality of life, particularly in terms of interpersonal relationships and self-fulfillment. The lifetime risk of developing an anxiety disorder exceeds 25%, making anxiety disorders one of the most prevalent psychiatric conditions and a leading cause of years of life lost due to disability or premature death worldwide. Of particular interest to the present study, aerobic exercise has been identified as an effective non-pharmacological tool for preventing and treating anxiety symptoms. Moreover, most studies evaluating the acute effect of aerobic exercise on anxiety symptoms have employed a variety of intensities, with no clear consensus on the optimal intensity for managing state anxiety symptoms. One of the factors influencing studies on the acute effects of aerobic exercise on state anxiety symptoms is the floor effect, where pre-exercise state anxiety symptoms are classified as mild. To address this, previous investigations have used methods to experimentally increase state anxiety symptoms. The advantage of this approach is that it allows for accuracy control of the intensity and duration of the anxiogenic stimulus. Objective: To investigate the dose-response relationship of acute aerobic exercise performed on a treadmill at different domains intensity (light, moderate, and vigorous) on state anxiety symptoms in healthy young individuals of both sexes, who were previously exposed to anxiogenic stimuli. Methods: This was a randomized crossover clinical trial. The sample consisted of 77 participants (39 women) with a median age of 25.53 years. The study was divided into five stages, conducted on separate days (48-96h). The first stage included a detailed explanation of the research, signing of the informed consent form, general anamnesis, assessment of trait anxiety symptoms, and cardiorespiratory fitness evaluation. The subsequent stages consisted of aerobic exercise sessions at light, moderate, and vigorous intensities on a treadmill, as well as a control session involving rest without exercise. The order of sessions was determined through counterbalanced randomization. The aerobic exercise sessions included a 5-minute warm-up at 3.8 km/h, a 30-minute main phase, and a cool-down phase with the same speed and Abstract xvi duration as the warm-up, totaling 40 minutes. The control session, consisting of rest without exercise, also lasted 40 minutes. The prescription of aerobic exercise was based on the percentage of each participant’s maximum heart rate achieved during the cardiorespiratory fitness assessment. State anxiety symptoms were assessed before exposure to unpleasant images, after exposure to unpleasant images, and after both the aerobic exercise and control sessions using the State-Trait Anxiety Inventory. For statistical analysis, a linear mixed model was used to compare the acute effects of treadmill aerobic exercise performed at different domains intensity on state anxiety symptoms. Results: Statistical analysis provided strong evidence of an interaction between time and session (F = 4.812; p-value < 0.001; ηp² = 0.051, small effect size) on participants’ state anxiety symptoms. Holm’s post hoc test revealed moderate evidence that light-intensity aerobic exercise (z = 3.187; p-value = 0.010) was superior to the control session, very strong evidence that moderateintensity aerobic exercise (z = 4.678; p-value < 0.001) was superior to the control session, and strong evidence that vigorous-intensity aerobic exercise (z = 3.470; pvalue = 0.004) was superior to the control session in reducing state anxiety symptoms induced by unpleasant images. Additionally, Holm’s post hoc test showed no differences between the three aerobic exercise intensities in reducing state anxiety symptoms. Statistical analysis also revealed no differences in the anxiolytic response elicited by different aerobic exercise intensities between sexes. Conclusions: Treadmill aerobic exercise sessions at light, moderate, and vigorous intensities were effective in reducing state anxiety symptoms following exposure to unpleasant images compared to the control session, with no differences between intensities. This indicates that there was no dose-response relationship between aerobic exercise intensity and the reduction of state anxiety symptoms. Furthermore, this effect was consistent across both sexes. These findings highlight the role of treadmill aerobic exercise as a viable strategy for managing anxiety symptoms, regardless of sex or exercise intensity. Therefore, health professionals can advise young and healthy individuals to perform aerobic exercise on a treadmill without the need for advice on a specific intensity of physical exercise.