Qualidade de vida relacionada à saúde em pacientes com glomerulopatias primárias
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Data
2023-08-31
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Universidade Federal de Goiás
Resumo
Introduction
Primary Glomerulopathies (PG) represent around 20% of prevalent cases of Chronic Kidney Disease (CKD) in the world and can be a cause of irreversible kidney damage, a source of personal suffering, and also a socioeconomic problem. This study aims to evaluate Health-Related Quality of Life (HRQoL) using Patient Reported Outcome Measures (PROM), and identify predictive factors associated with worse HRQoL in patients with GP.
Methods
A PROMIS (Patient-Reported Outcome Measurement Information System) instrument was completed by 46 patients with GP to assess HRQoL. Five domains were assessed: global health, fatigue, anxiety, depression and sleep impairment. Exploratory univariate statistical analyzes were performed followed by multiple linear regression analysis.
Results
Forty-six patients participated in the study. The mean age was 38.5 ± 16.4 years (ranging from 18 to 76 years). Female patients had worse scores for anxiety (p=0.044), depression (p=0.040) and sleep disorders (p=0.007). Patients younger than 60 years had worse anxiety scores (p=0.041). Better educational level was related to lower depression score (p=0.010). Obesity determined a worse physical health score (43.95 versus 40.14, p=0.022). The presence of pain, swelling, diagnosis time ≥9 months and Diabetes Mellitus (DM) were predictors of worse HRQoL in more than one evaluated domain.
Conclusion
The predictive variables of worse HRQoL in patients with PG were female gender, age younger than 60 years, lower educational level, overweight and obesity, need for emergency care, DM, diagnosis time ≥9 months and the presence of pain and edema at the time of the study. The study concludes that the assessment of HRQoL domains using MRRP makes it possible to identify factors that worsen HRQoL, allowing early intervention and improving patient care.
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Citação
BORGES, M. O. F. B. Qualidade de vida relacionada à saúde em pacientes com glomerulopatias primárias. 2023. 115 f. Dissertação (Mestrado em Ciências da Saúde) - Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, 2023.