Endoscopia em cães: aspectos macroscópicos e microscópicos da mucosa gástrica após intoxicação por tetracloreto de carbono e técnicas para detecção de helicobacter spp
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2012-11-30
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Universidade Federal de Goiás
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The mucosa is the most vulnerable gastric layer to damage, as it is the interface between the external environment and the body. For this reason, it presents specific mechanisms to maintain the integrity, but, when the triggering agent persists or is very aggressive, the defense mechanisms are overcome and mucosal injuries manifest. The endoscopy is the main technique for identifying this type of injury and it has the advantage of facilitating the material collection for the bacteriological and histological confirmation of the causing agent. The present study aimed to evaluate the gastroscopic and histological aspects of the gastric mucosa of dogs experimentally intoxicated with carbon tetrachloride and to identify the most efficient technique for detecting the bacteria of the genus Helicobacter in
the stomach of this animals species by comparing the techniques of cytology, fast
urease test and histological sections stained with HE, Giemsa and Warthin-Starry
(WS). In poisoned dogs there were hyperemia and hemorrhage by gastroscopy
and histology edema, hyperemia and hemorrhage. The Helicobacter detecting
prevalence was higher in the cytology exam and the sensitivity was higher in
histological sections stained with WS. It was concluded that orally administration of
CCl4 to dogs cause diffuse circulatory changes in gastric mucosa and the most
efficient technique to Helicobacter spp research is the cytology, being gastric
fundus the most suitable region for sampling.
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SANTOS, B. M. Endoscopia em cães: aspectos macroscópicos e microscópicos da mucosa gástrica após intoxicação por tetracloreto de carbono e técnicas para detecção de helicobacter spp. 2012. 90 f. Tese (Doutorado em Ciência Animal)–Universidade Federal de Goiás, Goiânia, 2012.