Concordância entre a angiografia por OCT e a avaliação multimodal na detecção de neovascularização de coroide no descolamento do epitélio pigmentado da retina
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Data
2019-06-25
Autores
Oliveira, Tauan de
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Universidade Federal de Goiás
Resumo
The aim of this study was to evaluate the agreement between multimodal imaging – MI
(fluorescein angiography, indocyanine green angiography, optical coherence tomography -
OCT) and optical coherence tomography angiography (OCTA) in the detection of choroidal
neovascularization (CNV) in patients with pigment epithelial detachment with
subretinal/intraretinal fluid (PED+F) and patients with PED without subretinal/intraretinal fluid
(PED-F). We evaluated 22 eyes of 15 patients were divided into 2 groups (PED+F and PED-F).
All patients underwent MI and OCTA with manual and automatic segmentations. OCTA
findings were conferred to MI findings and then analyzed for diagnostic concordance. In the
PED+F group (10 eyes) all studied eyes demonstrated CNV in MI. In manual segmentation
OCTA assessment, 9 of 10 eyes (90%) were detected with CNV. When evaluated by automatic
segmentation, 8 of 10 eyes (80%) revealed the presence of CNV. In the PED-F (12 eyes)
group, all eyes did not demonstrate CNV in MI and OCTA evaluations, either by manual or
automatic segmentation. The agreement between MI and OCTA has shown concordance (k:
0.908; 95% CI, 0.491-1.000); the evaluation of the agreement between the automatic and
manual segmentation also showed concordance (k: 0.904; 95% CI, 0.488-1.000). The solid
agreement between the multimodal imaging regarding the ability of OCTA to identify possible
initial CNV in a patient with PED-F was observed. OCTA accuracy in the detection of CNV was
95.45%. In addition, the solid agreement between manual and automatic segmentations to
identify CNV on OCTA was also shown.
Descrição
Palavras-chave
Descolamento do epitélio, Imagem multimodal, Angiografia por tomografia de coerência óptica, Pigmentado da retina, Neovascularização de coroide, Angiografia com indocianina verde, Angiografia com fluoresceína, Optical coherence tomography angiography, Multimodal imaging, Retinal pigment epithelium detachment, Choroidal neovascularization, Indocyanine green angiography, Fluorescein angiography
Citação
OLIVEIRA, T. Concordância entre a angiografia por OCT e a avaliação multimodal na detecção de neovascularização de coroide no descolamento do epitélio pigmentado da retina. 2019. 85 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2019.