Avaliação das Funções Cognitivas dos pacientes com Lúpus Eritematoso Sistêmico

Abstract

Introduction: Neurocognitive changes may hinder the autonomy and independence of patients diagnosed with Systemic Lupus Erythematosus (SLE), being considered as one of the main negative outcomes. Objectives: To evaluate the cognitive functions of patients diagnosed with active SLE and in remission, at the Rheumatology Outpatient Clinic of the Hospital das Clínicas, School of Medicine, Universidade Federal de Goiás. Methodology: This was a cross-sectional study, non-probabilistic sample and consecutive type. Mini Mental State Examination (MMSE), Five Digits Test (FDT) and Rey's Complex Figures (FCRey) were used in 83 patients, in the period from November 2021 to May 2022. Patients with depressive disorders and users of alcohol and other drugs were excluded. Results: In the assessed cognitive functions - attention, memory, language and executive functions - showed mild impairments, corroborating with previous studies. When comparing groups of patients with active SLE and in remission there was no significant difference (p>0.005) in relation to cognitive performance. Conclusion: In this sense, cognitive dysfunctions were present both in patients with active SLE and in remission, the results showed mild cognitive impairment in patients diagnosed with SLE.