Pseudodemência depressiva: fenomenologia psicopatológica e disfunções cognitivas
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2019-11-22
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Universidade Federal de Goiás
Resumo
Depressed patients often present cognitive impairment, including the possibility
of developing dementia - called Depressive Pseudodementia. Despite the
seriousness of the disease, publications with case presentation and
psychopathological discussion are scarce. Objectives: To describe
demographic, clinical and cognitive aspects in a group of patients with
depressive Pseudodementia, besides reporting possible associations between
Pseudodementia and the observed clinical findings. To perform a review on the
topic and discuss the relevance and validity of the diagnosis. Methods: This is
a descriptive study composed of patients with Pseudodementia Depressiva
treated in Goiás in the 2007-2017 period, presenting a discussion about the
results and comparison with other studies through literature review.
Multidimensional anamnesis was used for the collection of clinical history and
pathological antecedents. The diagnosis of Depressive Pseudodementia was
performed by Yousef pseudodementia scale (YPS); other psychiatric
diagnoses were defined by the DSM-5 and the severity of depression by the
Hamilton scale. The cognitive assessment was performed by the Mini-Mental
State Examination, functional questionnaire of Pfeffer and Clinical Dementia
Rating (CDR). Results: The sample consisted mainly of women (96.67%) with
a history of cardiovascular disease (43.33%) and neurological signs (53.33%).
Depression with melancholic features occurred in 56,66% of the cases and the
diagnosis of Bipolar Mood Disorder occurred in 100% of the sample. The main
cognitive dysfunctions found were inattention (100%) and short-term
hypomnesia (93.33%) corroborating the findings of the literature related to
cognitive impairment and depression. Conclusions: The demographic and
clinical aspects associated with Depressive Pseudo-dementia were female,
antecedent of cardiovascular disease and presence of neurological signs; the
basic psychiatric diagnosis was Bipolar Mood Disorder and the dominant
depressive phenotype was depression with melancholic characteristics; and
the central cognitive impairment was attention and short-term memory.
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REIMER, C. H. R. Pseudodemência depressiva: fenomenologia psicopatológica e disfunções cognitivas. 2019. 197 f. Tese (Doutorado em Ciências da Saúde) - Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, 2019.