Doutorado em Ciências da Saúde (FM)
URI Permanente para esta coleçãohttp://200.137.215.59/tede/handle/tde/243
Navegar
Submissões Recentes
Item type: Item , Avaliação clínica de pacientes submetidos a transplante hepático pela técnica de bypass no Hospital Geral de Goiânia(Universidade Federal de Goiás, 2026-06-26) Morais, Lúcio Kenny; Oliveira, Enio Chaves de; http://lattes.cnpq.br/7046861881778720; Oliveira, Enio Chaves de; http://lattes.cnpq.br/7046861881778720; Queiroz, Maria Conceição de Castro Antonelli Monteiro de; http://lattes.cnpq.br/3239526131529636; Almeida, Carlos Cristiano Oliveira de Faria; http://lattes.cnpq.br/7560379171515481; Garcia Neto, José; http://lattes.cnpq.br/1700159786639079; Penhavel, Felix Andre Sanches; http://lattes.cnpq.br/1628245325934303Introduction: Liver transplantation requires rigorous hemodynamic stability during the anhepatic phase. The use of veno-venous bypass (VVB) aims to mitigate systemic and portal congestion, protecting renal function and optimizing survival, although its actual impact remains debated. Objective: To analyze the association between veno-venous bypass, the occurrence of acute kidney injury (AKI), and overall survival in liver transplant recipients. Methodology: Retrospective cohort study of 63 patients, analyzed using Python 3.13.5. AKI was defined by KDIGO criteria (D1–D3). Survival was assessed by Kaplan-Meier curves and mortality risk by multivariate Cox regression, adjusted for MELD, ischemia time, and etiology. Results: The groups (With VVB: n=37; Without VVB: n=26) showed homogeneous demographic and etiological profiles (p>0,05). VVB use was not independently associated with AKI reduction (OR 0.63; p=0,679) or increased overall survival (p=0,758). Hepatocellular carcinoma (HCC) in the explant emerged as a significant protective predictor for survival (HR 0.06; p=0.020). Total ischemia time and portal hypertension showed clinical trends but no statistical significance after adjustment. Conclusion: Veno-venous bypass proved to be a safe perioperative support technique; however, it did not act as an independent determinant of overall survival or early renal function. Post-transplant prognosis in this cohort was primarily governed by biological factors and the underlying diagnosis (HCC), prevailing over the venous bypass technique employed.Item type: Item , Rastreamento de Chlamydia trachomatis e Neisseria gonorrhoeae em sítios orais e orofaríngeos em populações em vulnerabilidade socioeconômica: um estudo transversal(Universidade Federal de Goiás, 2026-05-30) Garcia, Weslley José Moreira; Cardoso, Juliana Lamaro; http://lattes.cnpq.br/0768752229180519; Amaral, Waldemar Naves do; ttps://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Sousa, Juarez Antônio de; http://lattes.cnpq.br/4484429936026476; Ferreira, Rui Gilberto; Tacon, Fernanda Sardinha de Abreu; Porto, Maria Laura de AlmeidaEMBARGADOItem type: Item , Repercussões cardíacas, respiratórias e metabólicas na coexistência de insuficiência cardíaca e diabetes mellitus tipo 2(Universidade Federal de Goiás, 2026-06-25) Vale, Gabriela de Oliveira Teles do; Rebelo, Ana Cristina Silva; http://lattes.cnpq.br/1542664015677213; Rebelo, Ana Cristina Silva; http://lattes.cnpq.br/1542664015677213; Campos, Mário Hebling; http://lattes.cnpq.br/7453152742646125; Oliveira, Jordana Campos Martins de; http://lattes.cnpq.br/0475222765257639; Vieira, Carlos Alexandre; http://lattes.cnpq.br/9938400037921472; Sousa, Wátila de Moura; http://lattes.cnpq.br/3360449775030988EMBARGADA.Item type: Item , Efeitos da suplementação de curcumina nos parâmetros metabólicos, inflamatórios e na morfologia do tecido adiposo de mulheres com obesidade grave(Universidade Federal de Goiás, 2025-11-28) Figueiredo, Nayra; Mota, João Felipe; http://lattes.cnpq.br/7179509845172692; Xavier, Flávia Campos Corgosinho; http://lattes.cnpq.br/3746419648548427; Xavier, Flávia Campos Corgosinho; Gamba, Patrícia Borges Botelho; Nascimento, Claudia Maria da Penha Oller do; Campos, Helioswilton Sales de; Masquio, Deborah Cristina LandiIntroduction: Obesity is characterized by chronic low-grade inflammation resulting from adipose tissue dysfunction, and the phase of life at obesity onset is an important contributing factor. Curcumin, a bioactive compound with metabolic and anti-inflammatory properties, appears to act on adipocytes and macrophages, mitigating the deleterious effects of the disease; however, human studies remain limited. Therefore, understanding the factors that may influence adipose tissue remodeling in response to chronic positive energy balance, as well as the phase of life at obesity onset, is essential to better explain the metabolic variability observed among individuals with obesity. Objective: To evaluate the effect of curcumin supplementation on metabolic, inflammatory, and morphological parameters of subcutaneous and omental adipose tissue in women with severe obesity. Additionally, to analyze the association between the phase of life at obesity onset and current age with the morphology of these adipose depots. Methods: Women with severe obesity (BMI ≥ 40 kg/m²), aged 20 to 59 years, who were candidates for bariatric surgery, were recruited. Clinical, anthropometric, and biochemical assessments were performed before and after supplementation with 1,500 mg/day of curcumin (98.75% curcuminoids) or placebo (cornstarch). Clinical evaluation included age, comorbidities, phase of life at obesity onset, and current medications. Anthropometric assessment included weight, waist circumference (WC), hip circumference (HC), and neck circumference (NC), followed by calculation of the waist-to-hip ratio (WHR). Biochemical tests assessed glycemic and lipid profile, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and high-sensitivity C-reactive protein (hs-CRP). Pro-inflammatory (PAI-1, leptin, TNF-α, IL-6) and antiinflammatory (adiponectin, IL-10) cytokines were analyzed using immunoenzymatic assays or multiplex technology. During bariatric surgery, the attending physician collected omental (OAT) and subcutaneous (SAT) adipose tissue biopsies, which were formalin-fixed and paraffinembedded. Histological slides were used to measure adipocyte area (hematoxylin-eosin) and total fibrosis percentage (picrosirius). Immunohistochemistry using CD68+ and perilipin-1 (PLIN-1) markers identified macrophages and cellular activity, respectively. For evaluation of the life stage of obesity development, participants were classified as Early (≤19 years) or Late (>19 years), and by current age as Younger (≥30 and <40 years) and Older (≥40 and <50 years). Statistical analyses were conducted using the Statistical Package for the Social Sciences (SPSS), version 21.0, with significance set at p<0.05. Results: Article 1: Twenty-four women participated, with a mean age of 34.33 years and BMI of 46.40 kg/m². Twelve-week curcumin supplementation reduced serum PAI-1 concentrations (p=0.015), with no differences in other glycemic, lipid, or inflammatory markers. Article 2: Eight women (mean age 34 years; BMI 48.04 kg/m²) underwent six months of supplementation prior to bariatric surgery, and their adipose tissues were compared. The curcumin group exhibited greater CLS density (p=0.045) and higher macrophage density in intravascular (p=0.023) and perivascular regions (p=0.021) of OAT. In SAT, greater macrophage density was identified within fibrotic areas (p=0.014). In addition to morphological changes, higher delta values for TG and VLDL-c were observed in women who received curcumin. Article 3: Thirty-four women participated (mean age 40.09 years; BMI 50.58 kg/m²). In OAT, greater macrophage density within fibrotic regions was observed in the “Late-Younger” group, and lower density in the “Early-Younger” group (p=0.005). Younger women presented a smaller omental adipocyte area (p=0.034). Unlike OAT, macrophages within fibrotic regions of SAT were influenced only by current age, with higher density in Younger women (p=0.000). Furthermore, only the life stage of obesity development influenced intravascular (p=0.004) and perivascular (p=0.029) macrophages in SAT. Conclusion: Our results demonstrate that twelve weeks of curcumin supplementation may exert cardioprotective effects in women with severe obesity, while prolonged supplementation may induce adipose tissue remodeling; however, further studies are needed to confirm whether such remodeling is beneficial. Moreover, the phase of life at obesity onset and current age may exert independent and combined effects that manifest differently in the morphology of omental and subcutaneous adipose tissues.Item type: Item , Paradigmas da inteligência artificial aplicada à oncologia: predição de sobrevida relacionada ao tratamento(Universidade Federal de Goiás, 2025-11-09) Costa, Webse da Mota; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; Sousa, Hidecazio de Oliveira; Alves, Edson Ferreira; Falone, Valdivina Eterna; Barbosa, Jacson RodriguesEmbargadoItem type: Item , Avaliação dos níveis salivares de cortisol e IgA como biomarcadores de estresse ocupacional em docentes de instituições de enisno superior(Universidade Federal de Goiás, 2025-10-30) Rocha, Jhonathan Gonçalves da; Guillo, Lídia Andreu; http://lattes.cnpq.br/3401436781775091; Guillo, Lídia Andreu; Barbosa, Maria Alves; Lacerda, Kênia Alves Pereira; Silva, Regisnei Aparecido de Oliveira; Neves, Roberpaulo AnacletoEmbargadoItem type: Item , Confiabilidade e legibilidade de modelos de linguagem de grande escala na orientação sobre exercício físico para pessoas com doença de Parkinson e epilepsia(Universidade Federal de Goiás, 2025-11-19) Silva, Rizia Rocha; Lira, Claudio Andre Barbosa de; http://lattes.cnpq.br/3289964716112944; Lira, Claudio Andre Barbosa de; http://lattes.cnpq.br/3289964716112944; Cordeiro, Douglas Farias; http://lattes.cnpq.br/5269312530540199; Pansani, Aline Priscila; http://lattes.cnpq.br/6385679829734771; Arida, Ricardo Mario; http://lattes.cnpq.br/8352745170435172; Teixeira-Machad, Lavínia; http://lattes.cnpq.br/5024139209411302ResumoItem type: Item , A somatização em crianças e adolescentes hospitalizados: corpo e sofrimento psíquico(Universidade Federal de Goiás, 2022-09-13) Sousa, Marylia Glenda Lopes Dep; Costa, Paulo Sergio Sucasas da; http://lattes.cnpq.br/9224543529268366; Dewulf, Nathalie de Lourdes Souza; http://lattes.cnpq.br/1244479719591748; Dewulf, Nathalie de Lourdes Souza; http://lattes.cnpq.br/1244479719591748; Costa Neto , Sebastião Benício da; http://lattes.cnpq.br/6712785343402727; Masson, Leilyane Oliveira Araújo; http://lattes.cnpq.br/9841067541213797; Marques, Solomar Martins; http://lattes.cnpq.br/5168936259198176; Costa, Lusmaia Damaceno CamargoResumoItem type: Item , Construção e Validação de Instrumento para Avaliação do Conhecimento de Pacientes com Glomerulopatias Primárias(Universidade Federal de Goiás, 2025-12-09) Santos, Luciana da Ressurreição; Pereira, Edna Regina Silva; http://lattes.cnpq.br/4503589425013098; Lopes, Flavio Marques; http://lattes.cnpq.br/1423301895802989; Lopes, Flavio Marques; http://lattes.cnpq.br/1423301895802989; Costa , Paulo Sérgio Sucasas da; http://lattes.cnpq.br/9224543529268366; Sousa, Ana Luiza Lima; http://lattes.cnpq.br/6578713509935374; Rodrigues, Cibele Isaac Saad; http://lattes.cnpq.br/7498326697611689; Pigozzi, ValériaResumoItem type: Item , Sífilis em Mulheres Trans em Goiás: Prevalência e Fatores Associados(Universidade Federal de Goiás, 2025-05-09) Alves, Juliana Burgo Godoi; Teles, Sheila Araújo; http://lattes.cnpq.br/4975298732179917; Teles, Sheila Araújo; http://lattes.cnpq.br/4975298732179917; Caetano, Karlla Antonieta Amorim; http://lattes.cnpq.br/0112036159794570; Santos, Paulie Marcelly Ribeiro dos; http://lattes.cnpq.br/7092622257221733ResumoItem type: Item , Ansiedade e raiva como moduladores do desempenho aeróbio e anaeróbio: um ensaio clínico randomizado e cruzado(Universidade Federal de Goiás, 2025-10-14) Costa, Thalles Guilarducci; Viana, Ricado Borges; http://lattes.cnpq.br/5907695308629566; Lira, Claudio Andre barbosa de; http://lattes.cnpq.br/3289964716112944; Lira, Claudio Andre barbosa de; Claudio Andre barbosa de Lira; Vieira, Carlos Alexandre; http://lattes.cnpq.br/9938400037921472; Santos, Daisy Motta; http://lattes.cnpq.br/2504359112669144; Deslandes, Andrea Camaz; http://lattes.cnpq.br/0855615218449231; Lobato, Núbia de Souza; http://lattes.cnpq.br/1922970859216238Embargada.Item type: Item , Gestantes portadoras de COVID-19: desfechos maternos e neonatais(Universidade Federal de Goiás, 2025-09-06) Tacon, Fernanda Sardinha de Abreu; Melo , Natália Cruz e; http://lattes.cnpq.br/3199361268323930; Ruano , Rodrigo; http://lattes.cnpq.br/3689773676364463; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Ferreira, Rui Gilberto; http://lattes.cnpq.br/3863770221302482; Sousa, Juarez Antônio de; http://lattes.cnpq.br/4484429936026476; Rios, Washington Luiz Ferreira; http://lattes.cnpq.br/7164542949212107; Nonato, Dejan Rodrigues; http://lattes.cnpq.br/6612365064988109Embargada.Item type: Item , Efeitos do treinamento de força e combinado sobre os parâmetros neuromusculares, cardiorrespiratórios, composição corporal e integridade celular de mulheres com câncer de mama em tratamento quimioterápico.(Universidade Federal de Goiás, 2025-09-27) Alves , Rafael Ribeiro; Del Vecchio, Fabricio Boscolo; http://lattes.cnpq.br/4479595583234972; Vieira, Carlos alexandre; http://lattes.cnpq.br/9938400037921472; Vieira, Carlos Alexandre; http://lattes.cnpq.br/3311692690861081; Cruz , Anderson Miguel da; http://lattes.cnpq.br/3056181392375690; Soares , Leonardo Ribeiro; http://lattes.cnpq.br/1610585108528260; Galvão , Luan de Sousa; Silva , Marcelo Henrique; http://lattes.cnpq.br/8086562277186741ResumoItem type: Item , Criação do primeiro Core set abrangente para pacientes com esclerose lateral amiotrófica utilizando a classificação internacional de funcionalidade, incapacidade e saúde(Universidade Federal de Goiás, 2025-08-13) Braga, Cristhiano Augusto de Oliveira Holanda; Diniz, Denise Sisterolli; http://lattes.cnpq.br/5139602841690387; Diniz, Denise Sisterolli; http://lattes.cnpq.br/5139602841690387; Zapata, Marco Túlio Antônio Garcia; http://lattes.cnpq.br/3672512339058369; Barbosa, Maria Alves; http://lattes.cnpq.br/5025797873585225; Oliveira, Acary Souza Bulle; http://lattes.cnpq.br/3911841387107665; Duarte, Pauliana Lamounier e Silva; http://lattes.cnpq.br/1956977228976455Embargada.Item type: Item , Evolução do sedentarismo em uma cidade de pequeno porte do interior do Estado de Goiás em um intervalo de treze anos(Universidade Federal de Goiás, 2020-11-18) Souza, Samanta Garcia de; Jardim, Paulo César Brandão Veiga; http://lattes.cnpq.br/2292209583823133; Jardim, Paulo César Brandão Veiga; http://lattes.cnpq.br/2292209583823133; Póvoa, Thaís Inácio Rolim; http://lattes.cnpq.br/7183213509383173; Gigonzac, Thaís Cidália Vieira; http://lattes.cnpq.br/0892495939159265; Jardim, Thiago de Souza Veiga; http://lattes.cnpq.br/2355748864825421; Ana Luiza Lima Sousa, Ana Luiza Lima Sousa; http://lattes.cnpq.br/6578713509935374Embargada.Item type: Item , Doenças tropicais negligenciadas: Análise da participação de organismos internacionais na implementação de políticas públicas e na legislação brasileira(Universidade Federal de Goiás, 2025-03-25) Silva, Walter de Paula; Oliveira, Ana Maria de; http://lattes.cnpq.br/0162295374076686; Zapata, Marco Tulio Antonio Garcia; http://lattes.cnpq.br/3672512339058369; Zapata, Marco Tulio Antonio Garcia; Barbosa, Maria Alves; Rocha, Danilo di Paiva Malheiros; Mrue, Fátima; Santos, Pedro Sérgio dosNeglected Tropical Diseases (NTDs) predominantly affect vulnerable populations in low- and middle-income countries, perpetuating health inequalities. This thesis presents a comparative analysis of public policies from the United Nations (UN) System, the World Health Organization (WHO), and the Pan American Health Organization (PAHO), alongside the Brazilian legislative framework related to NTDs. How have these regulations and public policies been implemented, and how can we improve them to ensure more effective and equitable responses? The general objective is to verify the existence of global and national norms and public policies aimed at addressing NTDs. The specific objectives are: to evaluate the implementation and impact of international norms and public policies related to NTDs developed by the United Nations (UN, WHO, and PAHO); to identify challenges, gaps, and suggestions in the implementation of global public policies on NTDs; to analyze the content, sufficiency, and quality of Brazilian legislative norms on NTDs at the Federal, State (focusing on Goiás), and Municipal (focusing on Goiânia) levels; and to propose strategic improvements to enhance public policies on NTDs. The research is justified by the persistent gap between the reality of NTDs and the insufficient implementation of public policies to address them. This study aims to strengthen the alignment between science, governance, and legislation, promoting more effective and equitable responses for historically neglected populations. The methodology was based on a scoping review of global policies and an integrative review of national legislation. The results indicate that, at the international level, policies on NTDs are limited and have low practical applicability. In Brazil, the omission of the National Congress results in fragmented actions that are misaligned with global guidelines. It is concluded that there is a significant gap both globally and nationally, emphasizing the urgent need for greater leadership from the Brazilian Parliament in addressing NTDs.Item type: Item , Expressão de individualidade biológica na periodontite usando algorítmo específico e o Método Salus(Universidade Federal de Goiás, 2025-08-18) Véras, Lázaro Gutto Fonseca; Roriz, Virgílio Moreira; http://lattes.cnpq.br/4602848040014140; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Reges, Rogério Vieira; Calaça, Germana Jayme Borges; Silva, Júlio Almeida; Guedes, Orlando AguirrePeriodontitis is a multifactorial inflammatory condition associated with the accumulation of dysbiotic biofilm and is highly prevalent among adults. It leads to the progressive destruction of periodontal tissues and may result in tooth loss. The Salus method employs Validated Computerized Dermatoglyphics (DIV) for biometric analysis of fingerprints through a specific algorithm within the Science software. This software has been used as a marker of biological individuality in various clinical conditions. This study aimed to determine dermatoglyphic patterns in individuals with a clinical diagnosis of periodontitis, applying a specific algorithm from the Science software. A total of 157 participants (30 females), aged between 30 and 64 years, were evaluated. The periodontitis group included 62 individuals (mean age: 53.7 years), while the control group, composed of healthy individuals, comprised 95 participants (55 females; mean age: 48.2 years). In the periodontitis group, clinical periodontal examination confirmed probing pocket depths of at least 4 mm (stages III and IV). In the control group, periodontal health was verified by the absence of periodontal pockets during probing. All participants underwent a digital fingerprint scan of all ten fingers using the Salus method to assess fingerprint pattern type and ridge count per finger. After fingerprint capture, the images were analyzed using the Science software algorithm, which included noise reduction, classification of fingerprint patterns, identification of cores and deltas, tracing of Galton lines, and ridge count processing. For the statistical analysis, the Kolmogorov-Smirnov, Student’s t-test, Mann-Whitney, and Fisher’s Exact tests were used. The significance level was set at 0.05. Comparative analysis between the groups with (n = 62) and without periodontitis (n = 95) showed similar demographic and anthropometric characteristics, except for age, which was significantly higher in the periodontitis group (p = 0.004). No significant differences were found in weight, height, or gender distribution, indicating homogeneity between the samples. Regarding qualitative dermatoglyphic patterns, the ulnar loop (LU) was the most frequent pattern across all fingers in both groups. The whorl (W) was the second most common pattern, with a frequency greater than 30% in specific fingers—MET2, MDT2, and MDT4 in the case group, and MET4, MDT2, and MDT4 in the control group. Other patterns, such as S-type whorl (WS), radial loop (LR), and arch (A), were infrequent. However, no statistically significant differences were observed in the distribution of fingerprint patterns between groups (p > 0.05), suggesting that periodontitis does not influence qualitative dermatoglyphic profiles. Quantitative analysis also showed similarities between groups. The average number of ridges per finger was comparable, with total ridge counts per hand and per individual nearly identical (113.7 in the periodontitis group and 112.6 in the control group). Delta distribution was also consistent with typical loop patterns, with one delta per finger being the most common. The mean number of deltas was 13.2 in the periodontitis group and 12.7 in the control group, with no statistically significant difference. The analysis of the total number of fingerprint patterns by type revealed similar distributions regarding medians and interquartile ranges, with no statistical differences across all categories assessed (W, WS, UL, RL, and A). Based on the methodology employed, it can be concluded that there is no significant association between dermatoglyphic patterns, both qualitative and quantitative, and the clinical presence of periodontitis. Despite the shared genetic origin between digital ridges and ectodermal structures, the data do not support the existence of a specific dermatoglyphic profile for individuals with periodontitis. The predominance of ulnar loop (UL) patterns and the similarity in ridge and delta counts between groups reinforce the absence of relevant phenotypic differences in digital patterns related to the disease. Thus, based on the evaluated sample and the method used, the validated computerized dermatoglyphics did not prove effective as a standalone biometric marker for identifying or screening individuals with periodontitis.Item type: Item , Aspectos clínicos e de neurodesenvolvimento em uma coorte de crianças potencialmente expostas ao Zika vírus na gestação, em Goiás(Universidade Federal de Goiás, 2022-07-09) Gomes, Maria Bárbara Franco; Turchi, Marilia Dalva; http://lattes.cnpq.br/3769826743537934; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Amaral, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579; Alves, Rosane Ribeiro Figueiredo; http://lattes.cnpq.br/8335736301768972; Marques, Solomar Martins; http://lattes.cnpq.br/5168936259198176; Sousa, Juarez Antonio de Sousa; http://lattes.cnpq.br/4484429936026476; Ferreira, Rui Gilberto; http://lattes.cnpq.br/3863770221302482Introduction: Zika virus (ZIKV) infection is on the World Health Organization's list of priority emerging diseases due to its potential to cause severe congenital infections and long-term development deficits in asymptomatic neonates. Objective: To describe the clinical and epidemiological characteristics and the neuropsychomotor development of a cohort of 111 children potentially exposed in utero to ZIKV. Method: This is a cohort of children of pregnant women with exanthematic disease and potentially exposed to ZIKV laboratory-confirmed by molecular and/or serological tests and children with dysmorphias suggestive of Congenital Zika Syndrome (CZS), in the State of Goiás, in the period from 2016 to 2020, followed in reference services for high-risk pregnancy, which were measured anthropometric parameters, morphological and functional alterations were investigated and submitted to clinical evaluation and neurobehavioral development with application of the Bayley III neurodevelopmental scale Results: We followed 86 children, 58 mothers with positive tests for prenatal ZIKV and 14 children with dysmorphias suggestive of CZS. Of these, in 52, the Bayley III tests were applied, an instrument for evaluating child development from 2017 to 2020. The absolute risk of microcephaly among children whose mothers were confirmed and suspected with ZIKV was 5.4%. 15.5% of children of pregnant women suspected or confirmed from ZIKV exposure had some dysmorphia related to CZS. We observed the occurrence of 86.5% delay in at least one of the Bayley III domains and in children without microcephaly were delays in the cognitive domain 12.8%, language 33.3% motor domain 25.6%, socioemotional domain 17.9% and global adaptive behavior 76.9%. Conclusion: Symptomatic and children apparently asymptomatic, had some degree of delay or dysfunction, and should be accompanied by specialized teams since follow-up with appropriate interventions can minimize sequelae and correct deviations from normality.Item type: Item , Radioterapia adjuvante para câncer de colo uterino em estágios iniciais de risco intermediário pós-histerectomia radical(Universidade Federal de Goiás, 2025-08-27) Silva, Pedro Henrique Costa Matos da; Santos, Rodrigo da Silva; http://lattes.cnpq.br/4806187026900959; Reis, Angela Adamski da Silva; http://lattes.cnpq.br/3243656364470085; Reis, Angela Adamski da Silva; Conde, Délio Marques; Franchi, Leonardo Pereira; Silveira, Luciana Carvalho; Moreira, Andre Luis EliasEmbargadoItem type: Item , Prevalência e Espectro de Fenótipos Cognitivos na Esclerose Múltipla e Fatores de Risco Relacionados(Universidade Federal de Goiás, 2022-12-14) Rabelo, Andréia Costa; Diniz, Denise Sisterolli; http://lattes.cnpq.br/5139602841690387; Caixeta, Leonardo Ferreira; http://lattes.cnpq.br/9536747113677509; Caixeta, Leonardo Ferreira; Teixeira Júnior, Antônio Lúcio; Damasceno, Benito Pereira; Ferreira, Sandra de Fátima Barboza; Schewinsky, Sandra Regina: Cognitive impairment (CI) is recognized as a prevalent and disabling symptom in Multiple Sclerosis (MS), compromising activities of daily living (ADLs), employability, social life and adherence to treatment, sometimes more intensely than physical limitations themselves. Objectives: This study aimed is describe the spectrum and prevalence of CI phenotypes in MS in patients from a referral center in the city of Goiânia, potential risk factors and how they may be related to the evolution of the disease. Methods: A sample of 117 people with MS (PwMS) from a university reference center was selected, diagnosed according to McDonald’s revised criteria and evaluated cognitively, psychologically and functionally with the following instruments: Brief Repeatable Battery of Neuropsychological Tests in Multiple Sclerosis (BRB-N), Beck Depression Inventory- 2ª edition (BDI-II), Beck Anxiety Inventory (BAI) and Expanded Disability Status Scale (EDSS). Results: We found CI in 60.7% of the sample, with 25.6% classified as mild and 35.1% severe, of which 17.1% met criteria for dementia. Conclusions: MS generates mild cognitive impairment (MCI) in patients and can increase the possibility of dementia with MS dementia being specific and associated with the motor severity of the disease.