Ocorrência da infecção por Trichomonas vaginalis em mulheres HIV positivas e negativas atendidas em hospitais de referência em Goiânia, Goiás, Brasil.
Data
2008-12-17
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Universidade Federal de Goiás
Resumo
This study evaluated the frequency of Trichomonas vaginalis infection in
human immunodeficiency virus positive (HIV+) and negative (HIV-) women in
Goiania, Goiás, Brazil, comparing the presence of the parasite in the two groups and
correlating it with the conditions of immunodeficiency present in these women. The
diagnostic techniques used, wet mount microscopy, culture and cytology, were also
evaluated, and the principal inflammatory alterations in the two groups were
assessed. The HIV+ samples (test group) were collected at the Hospital of Tropical
Diseases and in the Maternal and Child Healthcare Hospital, whereas the HIVnegative
samples (control group) were collected at the Maternity Hospital. Swabs
were used for wet mount microscopy (saline solution) and for culture (Diamond s
medium), and Ayre s spatula and brush were used for the cytology smears, which
were fixed using a commercial fixative. A total of 237 samples were analyzed, 125
HIV-positive test samples and 112 HIV-negative controls. The overall frequency of T.
vaginalis was 13.9%, 18.4% in the HIV+ and 8.9% in the HIV- group. This difference
was statistically significant (p<0.05); however, the infection was not associated with
immunodeficiency according to CD4, viral count and lymphocytes. There was a
significant difference in the prevalence of the parasite between HIV+ and HIVpregnant
women (22.6% versus 12.5%). Culture identified a frequency of T.
vaginalis of 13.9%, while cytology identified a rate of 13.5% and wet mount
microscopy 11.4%. Perinuclear halos were the most frequent inflammatory
alteration; however, there was no difference between the groups
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Citação
LEMOS, Patrícia Abreu Pinheiro de. The Prevalence of Trichomonas vaginalis in HIV positive and HIV negative women attending referral hospitals in Goiania, Goias, Brasil. 2008. 83 f. Dissertação (Mestrado em Medicina) - Universidade Federal de Goiás, Goiânia, 2008.