Mpox e Mpox em PVHA: um estudo transversal
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Data
2024-11-08
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Universidade Federal de Goiás
Resumo
Introduction: The Mpox virus was discovered in 1958 in non-human primates and later
identified in a 9-year-old child in the Democratic Republic of Congo, remaining
restricted to the African continent and primarily affecting children. In 2022, it crossed
borders and was associated with outbreaks in different countries, with a different
clinical and epidemiological profile than what had been observed, this time affecting
Men Who Have Sex with Men (MSM), with genital and anal lesions and
disproportionately affecting People Who Live with HIV (PLHIV). The main objective
of this study was to compare the epidemiological and clinical characteristics of patients
coinfected with Mpox/HIV/AIDS with those infected only with Mpox. Methods: This
is a retrospective and cross-sectional study. All confirmed cases of Mpox from patients
residing in Goiânia, Goiás, Brazil, between the months of June 2022 and June 2023
were included for analysis. The patients were divided into 3 groups, those with only
Mpox, those with Mpox and HIV, and those with Mpox and AIDS, subsequently
comparing the epidemiological and clinical characteristics. Results: Of a total of 398
confirmed cases, 223 (52%) were in PLHIV, of these 14 (6%) were in the AIDS phase.
There were 175 cases in patients with only Mpox and of these, only 37 (21.14%) were
using PrEP for HIV. Different clinical characteristics were identified between the
groups, with statistical significance for Localized Lymphadenopathy found more
frequently in the group with only Mpox and Genital Lesions being observed more
commonly in cases with Mpox/AIDS. The presence of coinfection with another STI
occurred more frequently in Mpox/HIV, with syphilis being the most common STI.
Finally, all cases evolved to cure. Conclusions: The Mpox outbreak affected PLHIV in
Goiânia more frequently, who more commonly presented another STI, greater genital
involvement, and a lower proportion of localized lymphadenopathy and among the
patients infected with only Mpox a very low proportion was using PrEP for the HIV
virus, differing from what is found in developed countries.
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Citação
COUTINHO, J. V. S. C. Mpox e Mpox em PVHA: um estudo transversal. 2024. 67 f. Dissertação (Mestrado em Medicina Tropical e Saúde Pública) - Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, 2024.