Atividade larvicida do extrato bruto de Swinglea glutinosa evidenciada pelas alterações morfohistológicas em larvas de Aedes aegypti (Diptera, Culicidae)
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2015-06-29
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Universidade Federal de Goiás
Resumo
Aedes aegypti is the major vector of dengue, urban yellow fever and emerging
arboviruses in Brazil, as chikungunya fever. This mosquito is adapted to the urban
environment, and is an important factor for the maintenance of its kind, the long
period of quiescence of eggs, which was an extraordinary physiological adaptation to
different climatic and dietary factors. Approximately 2.5 billion people live in endemic,
exposed to dengue transmission countries. The best solution would be to control
multivalent vaccines to existing serotypes. Tetravalent vaccines are being tested in
several countries, including Brazil. However, recently it described a fifth serotype,
and this can probably extend the course of research. So how vaccines are not ready
for use, dengue control has been done by the intervention of actions against the
vector, Ae. aegypti. Among the actions, the use of synthetic chemical insecticides
has been the main, it emerged mosquito susceptibility of modification in many
Brazilian cities and later confirmation of resistance status. This paper proposes the
search for alternatives, through prospecting of natural compounds insecticides for the
control of Ae. aegypti. Among the actions, the use of synthetic chemical insecticides
has been the main. However, with the continuous use of the same product in some
brazilians municipalities seemed evidence of mosquito susceptibility modification and
subsequently confirm the resistance status. Among, measures control alternatives
Ae. aegypti is prospecting for natural compounds insecticides. This work proposes
the study of crude ethanol extract (c.e.e.) the result of Swinglea glutinous as larvicide
and it showed CL50 and CL90 of 74.4 ppm to 125.2 ppm for third instar larvae of Ae.
aegypti, besides the toxicity effect on these intestinal cells larvae investigated by
morphohistological study. The morphological changes that are intensified with
increasing time of exposure to the larvae of c.e.e. were visualized particularly in the
posterior region of the midgut, included folding of the peritrophic matrix, increasing
subperitrophic space, cytoplasmic vacuolization, reduction of the microvilli cells. What
characterized and checked the larvicidal effect of c.e.e. demonstrating its potential
use for controlling Ae. aegypti.
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CABRAL, S. S. Atividade larvicida do extrato bruto de Swinglea glutinosa evidenciada pelas alterações morfohistológicas em larvas de Aedes aegypti (Diptera, Culicidae). 2015. 42 f. Dissertação (Mestrado em Biologia da Relação Parasito-Hospedeiro) - Universidade Federal de Goiás, Goiânia, 2015.