Análise do perfil epidemiológico, clínico e patológico de pacientes com líquen plano oral
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2020-01-27
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Universidade Federal de Goiás
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INTRODUCTION: Oral lichen planus (OLP) is an immunomediated disease whose diagnosis and treatment can be challenging for clinicians and pathologists. OBJECTIVE: This case series aimed to evaluate the epidemiological, clinical and pathological profile of patients with OLP according to the criteria established by the American Academy of Oral and Maxillofacial Pathology (AAOMP/2016). METHODOLOGY: Sampling was initially established from the analysis of the annotations of the medical records and histopathological reports of patients diagnosed with OLP at the Centro Goiano de Doenças da Boca (CGDB) from 1998 to 2018. Subsequently, the clinical and demographic data of the patients lesions (location and clinical characteristics of the lesion) and the microscopic characterization of the specimens followed the criteria proposed by AAOMP / 2016. In addition, patients were invited to follow up and apply the Oral Health Impact Profile (OHIP-14) instrument to assess quality of life. Statistical analysis was descriptive with absolute and relative values and the Shapiro-Wilk test was used to assess the normality of the data collected in the OHIP-14 and then the groups were compared using the Mann-Whitney test. RESULTS: This case series (n=41) consisted mainly of women (n=29; 70.7%) with a mean age of 45 (±13.6) years. The buccal mucosa (68.2%) was the most affected site. Reticular (n=23; 56.1%) and erosive (n=14; 34.3%) OLP were the most frequent. According to OHIP-14, individuals with OLP at multiple sites of the oral cavity had worse values in the handicap domain (p=0.03). In addition, those patients who did not respond to corticosteroids had higher scores in the psychological discomfort domain (p=0.04). CONCLUSION: The findings of the present study using the AAOMP/2016 criteria are similar to other case series and retrospective studies reported in the literature, where OLP is more common in middle-aged women in reticular form. In addition, OLP, in its most severe clinical forms, seems to influence patients' quality of life.
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LIMA, S. L. G. Análise do perfil epidemiológico, clínico e patológico de pacientes com líquen plano oral. 2020. 65 f. Dissertação (Mestrado em Odontologia) - Universidade Federal de Goiás, Goiânia, 2020.