Mestrado em Odontologia (FO)

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    Avaliação do potencial da tanshinona para inibir a perda óssea induzida por inflamação: análise microtomográfica em modelo murino de calvária
    (Universidade Federal de Goiás, 2026-05-25) Melo, Natália de Queiroz; Souza, Pedro Paulo Chaves de; http://lattes.cnpq.br/7295422299985847; Freitas, Gileade Pereira; http://lattes.cnpq.br/8696317917676943; Roriz, Virgilio Moreira; Sousa, Hidecazio De Oliveira; Freitas, Gileade Pereira
    Introduction. Diseases characterized by bone destruction and loss, especially those associated with inflammatory processes, significantly compromise the quality of life of individuals, justifying the search for therapeutic agents capable of modulating bone resorption. In this context, tanshinone stands out as a natural bioactive compound with anti-inflammatory, antioxidant, and bone metabolism-modulating properties, showing potential action in regulating osteogenic activity. Additionally, the use of molecules derived from bacterial components has enabled a better understanding of the mechanisms involved in the host immune response and bone resorption processes. Among these molecules, Pam2CSK4, a synthetic lipopeptide, stands out as a potent inducer of inflammatory response and bone resorption. Objective. This study aimed to evaluate the effect of Pam2CSK4 on the induction of bone resorption and the effect of tanshinone IIA (TII-A) on the reduction of bone resorption in an experimental mouse calvaria model. Methodology. An experimental, in vivo laboratory study with a blinded design was conducted. Male mice were used, distributed into three groups (n=6): a control group (CONTROL), which received saline solution; a group subjected to inflammatory induction (Pam2CSK4); and a group treated with TII-A associated with inflammatory induction (TII-A). Through microtomographic analysis, parameters related to trabecular bone microarchitecture were evaluated, such as bone volume (BV), percentage of bone volume (BV/TV), number of trabeculae (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp). Results. A significant reduction was observed in some of the evaluated parameters. The Pam2CSK4 and TII-A groups showed a significant reduction in bone volume (BV) (p = 0.025 and p = 0.012, respectively) and percentage of bone volume (BV/TV) (p = 0.025 and p = 0.012, respectively) compared to the control group, with no significant differences between the Pam2CSK4 and TII A groups (p = 0.897). Trabecular thickness (Tb.Th) also showed significant differences compared to the control group, both in the Pam2CSK4 group (p < 0.001) and in the TII-A group (p = 0.012). However, no statistically significant differences were observed between the Pam2CSK4 and TII-A groups (p = 0.054). Conversely, the number of trabeculae (Tb.N) did not show a statistically significant difference between the groups evaluated (p = 0.059). Similarly, the trabecular separation parameter (Tb.Sp) also did not show significant differences when comparing the control, Pam2CSK4, and TII-A groups (p = 0.256). Conclusion. The experimental model induced by Pam2CSK4 was effective in promoting changes related to bone resorption in the calvaria of the animals evaluated. However, TII-A did not demonstrate a significant antiresorptive effect under the conditions established in this study. The findings identified in the microtomographic analysis regarding changes in bone microarchitecture in the study highlight the complexity of the pharmacological modulation of inflammatory bone loss and reinforce the need for future investigations to better elucidate the therapeutic potential of the substance studied
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    Aplicação de modelos tridimensionais na avaliação de preparo coronário
    (Universidade Federal de Goiás, 2026-02-19) Jardim, Tainá Itana Coelho Lima da Veiga; Jardim, Alexandre Fausto da Veiga; http://lattes.cnpq.br/4318738007975635; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; Decurcio, Daniel de Almeida; Serpa, Giulliano Caixeta
    Embargo
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    Influência da estratégia adesiva na resistência de união ao esmalte tratado com infiltração resinosa
    (Universidade Federal de Goiás, 2026-02-27) Morais, Gabriela Rodrigues Silva de; Veríssimo, Crisnicaw; https://lattes.cnpq.br/2811678434269373; Veríssimo, Crisnicaw; Mendes, Gustavo Adolfo Martins; Faria, Patrícia Corrêa de
    Embargo
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    Caracterização sociodemográfica, clínico-patológica e de fatores que impactam na sobrevida de pacientes com carcinoma de nasofaringe diagnosticados e tratados em um centro de alta complexidade em oncologia do sus: coorte retrospectiva
    (Universidade Federal de Goiás, 2026) Moreira, Victor Hugo Lopes de Oliveira; Mendonça, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847; Mendonça, Elismauro Francisco de; Arantes, Diego Antônio Costa; Salustiano, Luciana Ximenes; Morais, Marilia Oliveira; Nogueira, Túlio Eduardo
    Introduction: Nasopharyngeal carcinoma (NPC) is a malignant neoplasm arising from the nasopharyngeal epithelium, frequently associated with Epstein–Barr virus (EBV) infection. Although its global incidence is low and largely concentrated in East and Southeast Asia, NPC is uncommon in non-endemic regions such as Brazil. Given the scarcity of studies in non-endemic settings, it is relevant to characterize the profile of Brazilian patients with NPC and to identify prognostic factors within the context of care provided by Brazil’s Unified Health System (SUS). Objective: To characterize the sociodemographic and clinicopathological profile of patients diagnosed with NPC and treated at a SUS High-Complexity Oncology Center (CACON), and to evaluate factors affecting overall survival and disease-free survival. Methods: This retrospective observational cohort study included 150 patients diagnosed with NPC between 2006 and 2018 at the Araújo Jorge Cancer Hospital, Goiânia, Brazil. Sociodemographic variables, clinicopathological characteristics, treatment data, adherence to the Preventive Dental Protocol (PDP), and survival outcomes were collected from medical records within the Hospital Cancer Registry (HCR). Overall survival (OS) was defined as the time from diagnosis to death, and disease-free survival (DFS) as the time from the end of treatment to recurrence/ progression. Survival curves were estimated using the Kaplan–Meier method and compared with the log-rank test. Multivariable survival analysis was performed using Cox proportional hazards regression. Associations between categorical variables were assessed using the chi-square test. Statistical significance was set at p < 0.05 with a 95% confidence interval. Results: The cohort was predominantly male (63.3%), with a median age of 51 years and a predominance of mixedrace (pardo) individuals (56.7%). The mean time to definitive diagnosis was 5.5 months. Most tumors were staged as T4 (34.7%) with nodal involvement classified as N3 (34.7%). The most frequent histological subtype was nonkeratinizing undifferentiated carcinoma (49.3%). EBV status was available for 20% of the sample and showed no significant association with histological subtype or prognosis (p > 0.05). The main therapeutic modality was concurrent chemoradiotherapy (64.7%). The most prevalent adverse effects were mucositis (48%), dysphagia (36.7%), and xerostomia (26%). Mean follow-up was 77.16 months (62.64–91.69). A total of 84 deaths were recorded, with an overall survival rate of 44.5%. Adherence to the PDP was observed in 78% of patients and was significantly associated with higher OS (p < 0.01). OS was also associated with age (p = 0.028), sex (p = 0.02), and T (p < 0.01) and N (p < 0.01) staging. DFS was statistically significant in relation to M staging (p < 0.01). Sex, T and N staging, and adherence to the PDP were independent prognostic factors impacting OS. Conclusion: In a SUS CACON setting, NPC was most often diagnosed at advanced stages, which negatively affected survival. Adherence to the PDP was associated with improved OS, suggesting that dental follow-up is essential in oncologic care.
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    Avaliação clínica do efeito da distribuição dos implantes na retenção e estabilidade de overdentures mandibulares retida por 4 mini-implantes
    (Universidade Federal de Goiás, 2026-02-26) Nascimento, Lays Noleto; Leles, Cláudio Rodrigues; http://lattes.cnpq.br/6740286066154410; Nogueira, Túlio Eduardo; Silva, Lucas José de Azevedo
    Retention and stability are essential determinants for the clinical performance and satisfaction of users of implant-retained mandibular overdentures. Despite advances in the use of mini-implants, gaps remain regarding the influence of the geometric distribution of these implants on long-term clinical and biomechanical outcomes. Thus, the aim of this study was to evaluate the influence of mini-implant distribution on the retention and stability of mandibular overdentures retained by four mini-implants after four years of follow-up. This is an observational study, derived from a previous randomized clinical trial. Thirty-one edentulous patients rehabilitated with mandibular overdentures retained by four mini-implants were evaluated and classified into groups with favorable and unfavorable polygonal distribution based on three-dimensional tomographic analysis. The variables analyzed included geometric and biomechanical parameters, frequency and time of replacement of retentive matrices, clinical stability of the prosthesis, retention force, bite force until displacement, and patients' subjective perception of retention and stability of the overdenture. Data were analyzed using descriptive and inferential statistics, with normality tests, parametric or non-parametric bivariate comparisons, correlation analysis, internal consistency assessment, and cluster analysis (k-means), adopting a significance level of 5% (α = 0.05). Unfavorable polygonal distributions were associated with a higher incidence of replacements of retentive matrices and a shorter time of use of the last installed matrix (p < 0.05). In addition, patients in this group reported a greater perception of instability and displacement of the overdenture. No significant differences were observed between the groups regarding clinical stability tests, retention force, and bite force until displacement. It is concluded that patients' subjective perception of retention and stability, and the need for matrix replacement in mandibular overdentures retained by four mini-implants, are more strongly associated with the geometric distribution of the implants than with the isolated magnitude of the retentive force, highlighting the importance of adequate biomechanical planning for long-term clinical success
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    Prognóstico de mini-implantes dentários em reabilitações com overdentures maxilares: uma revisão sistemática
    (Universidade Federal de Goiás, 2026-03-24) Silva, Camila Alvarenga da; Costa, Nádia do Lago; https://lattes.cnpq.br/9120865567187887; Costa, Nádia do Lago; Fernandes, Aline Úrsula Rocha; Morais, André Luiz Gomide de
    Embargo
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    Avaliação dos efeitos térmicos e histológicos do laser de diodo (980nm) e do bisturi elétrico na mucosa jugal de ratos: estudo experimental
    (Universidade Federal de Goiás, 2026-02-27) Costa, Joyce Carrijo Rodrigues Silva; Miguel, Marina Pacheco; https://lattes.cnpq.br/3078760368293415; Roriz, Virgilio Moreira; https://lattes.cnpq.br/4602848040014140; Roriz, Virgilio Moreira; Ferraz, Emanuela Prado; Silva, Brunno Santos de Freitas
    Embargo
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    Abordagem da prática baseada em evidências nos programas de pós-graduação stricto sensu em odontologia brasileiros
    (Universidade Federal de Goiás, 2026-02-10) Branquinho, Amanda Caroline de Moraes; Faria, Patrícia Corrêa de; https://lattes.cnpq.br/8411040100439650; Faria, Patrícia Corrêa de; Freitas, Gileade Pereira; Mendes, Gustavo Adolfo Martins
    Embargado
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    O efeito do uso de canabinoides associado ou não à terapia de fotobiomodulação no controle da mucosite oral em pacientes com câncer de cabeça e pescoço: Ensaio clínico randomizado cruzado duplo cego controlado
    (Universidade Federal de Goiás, 2025-03-10) Pires, Raquel Barbosa; Mendonça, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847; Mendonca, Elismauro Francisco De; http://lattes.cnpq.br/2305019128015847; Arantes, Diego Antonio Costa; http://lattes.cnpq.br/8341286790648954; Silva, Geisa Badauy Lauria; http://lattes.cnpq.br/0494060316172926
    Resumo
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    Interferência da cerâmica dental na aferição da saturação de oxigênio usando oxímetro de pulso
    (Universidade Federal de Goiás, 2021-12-17) Marra, Igor Gomide; Alencar, Ana Helena Gonçalves de; http://lattes.cnpq.br/2039898015468283; Silva, Julio Almeida; http://lattes.cnpq.br/1022830186974104; Silva, Julio Almeida; http://lattes.cnpq.br/1022830186974104; Decúrcio, Daniel de Almeida; http://lattes.cnpq.br/4640062828556657; Guedes, Orlando Aguirre; http://lattes.cnpq.br/3219560690903434
    Objective: To evaluate the interference of dental ceramics in the measurement of systemic oxygen saturation in the finger using a pulse oximeter. Materials and method: Thirty samples of Ips e.max lithium disilicate ceramic, of low, medium, and high translucency in thicknesses 2.0 ± 0.5mm and 4.0 ± 0.5mm, glazed on one side and blasted with oxide aluminum on the other. Using the BCI 3301 portable pediatric pulse oximeter, an initial reading of the participant's oxygen saturation (SaO2) and heart rate (bpm) was performed, at rest, in the little finger (Control group). Waited 30 seconds after reading stabilization to record the data. Then, the ceramic samples were interposed between the finger and the pulse oximeter sensor, with the glaze side positioned towards the light emitting source, and again the data were collected (Experimental groups). Statistical analysis was performed using the Statistical Package for Social Sciences software, version 20 (SPSS, Chicago, IL). The mean and standard deviation of SaO2 were calculated and the Mann-Whitney test was applied, considering significant p values < 0.05. Results: The mean of SaO2 obtained in the control group was 97.3 ± 0.58%. In the low translucency group, the mean SaO2 was 97.8% ± 0.45 for both thicknesses and in the medium translucency group with a thickness of 2.0 ± 0.5mm it was 98 ± 0.0%, and with thickness of 4.0 ± 0.5mm was 97.6% ± 0.55. In the high translucency group with a thickness of 2.0 ± 0.5mm it was 97.8 ± 0.45%, and with a thickness of 4.0 ± 0.5mm it was 97.4 ± 0.55%. There was no significant difference between the means of SaO2 of the Control Group and the experimental ones (p >0.05). Conclusion: The thickness and translucency of Ips e.max lithium disilicate dental ceramics, placed between the finger and the sensor, did not interfere in the measurement of oxygen saturation recorded by the pulse oximeter.
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    Efeito da ativação ultrassônica na cimentação de pinos de fibra de vidro: análise por tomografia e microscopia óptica
    (Universidade Federal de Goiás, 2025-07-10) Oliveira, Patrick Domingues de; Decurcio, Daniel de Almeida; http://lattes.cnpq.br/4640062828556657; Decurcio, Daniel de Almeida; Serpa, Giulliano Caixeta; Estrela, Carlos
    Ultrasonic activation (UA) has been proposed as a strategy to enhance endodontic sealer penetration and improve marginal adaptation; however, its effect on the cementation of intraradicular posts remains uncertain. This study evaluated, using cone-beam computed tomography (CBCT) and optical microscopy, the occurrence of failures in the cementation of glass fiber posts subjected to different UA protocols. Forty bovine roots were standardized in length and randomly assigned to four groups (n = 10): G1 – no activation; G2 – sealer activation; G3 – post activation; and G4 – combined activation (sealer and post). The posts were anatomically shaped and cemented with a self-adhesive and self-etching resin cement according to each group’s protocol. After 30 days of storage in saline solution, the samples were analyzed by CBCT to detect failures at the sealer-dentin interface in the cervical, middle, and apical thirds. Subsequently, the roots were sectioned for microscopic analysis of marginal adaptation and classification of failures based on the number of walls exhibiting gaps at the adhesive interface. Statistical analysis (Kruskal-Wallis test; p < 0.05) revealed no significant differences among the groups. It was concluded that the tested UA protocols did not significantly influence the quality of post cementation.
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    Avaliação do deslocamento de caninos e pré-molares intraósseos e primeiros molares permanentes superiores após expansão rápida da maxila
    (Universidade Federal de Goiás, 2025-03-10) Mialichi, Mikaella Gomes; Valladares Neto, Jose; http://lattes.cnpq.br/3536721807622509; Silva, Maria Alves Garcia Santos; Arruda, Karine Evangelista Martins; http://lattes.cnpq.br/8547595943761788; Arruda, Karine Evangelista Martins; Sousa, Thiago Oliveira; Almeida, Guilherme de Araújo
    Embargado
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    Resina flow utilizada como agente de cimentação: microdureza e densidade de ligações cruzadas- estudo in vitro
    (Universidade Federal de Goiás, 2025-02-26) Borges, Marina de Almeida Silva; Lopes, Lawrence Gonzaga; http://lattes.cnpq.br/8698234314492960; Lopes, Lawrence Gonzaga; http://lattes.cnpq.br/8698234314492960; Chaves, Ana Paula Rodrigues de Magalhães; http://lattes.cnpq.br/3319767342751521; Carvalho, Andreia Assis; http://lattes.cnpq.br/6623092760228722
    Embargada.
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    Efetividade do selamento de canais radiculares ovais com diferentes técnicas e cimentos de silicato de cálcio, usando navegação em imagens tridimensionais
    (Universidade Federal de Goiás, 2025-03-07) Amaral, Maria Teresa Andrade do; Decurcio, Daniel de Almeida; http://lattes.cnpq.br/4640062828556657; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Estrela, Carlos; http://lattes.cnpq.br/3611967334176683; Silva, Julio Almeida; http://lattes.cnpq.br/1022830186974104; Serpa, Giulliano Caixeta; http://lattes.cnpq.br/2374096529348644
    Embargada.
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    Relação entre a experiência dos ortodontistas e a solicitação de tomografia computadorizada de feixe cônico (TCFC) integrada ao plano de tratamento ortodôntico com alinhadores: estudo transversal
    (Universidade Federal de Goiás, 2025-02-18) Fernandes, Alessah Carolyna de Andrade; Lenza, Maurício Guilherme; http://lattes.cnpq.br/8565025682513578; Silva, Fernanda Paula Yamamoto; http://lattes.cnpq.br/0511229119340734; Silva, Fernanda Paula Yamamoto; Lenza, Marcos Augusto; Jardim, Alexandre Fausto da Veiga
    embargo
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    Análise de disposição a pagar pela radiografia panorâmica e tomografia computadorizada de feixe cônico no tratamento com implantes para espaço desdentado unitário posterior
    (Universidade Federal de Goiás, 2023-03-03) Prado, Thayse Bernardes de Paiva; Silva, Fernanda Paula Yamamoto; http://lattes.cnpq.br/0511229119340734; Silva, Fernanda Paula Yamamoto; Perazzo, Matheus de França; Dias, Danilo Rocha
    Planning an implant rehabilitation requires a detailed diagnosis, especially in terms of bone quantity and quality, which makes imaging tests indispensable in the diagnosis and surgical planning of implant placement. These tests have costs that, in most cases, are the responsibility of the patient. Economic evaluations of PAD can contribute to the assessment of patient preference, in financial terms. Objective: The aim of this study is to evaluate the patient's willingness to pay (WTP) for panoramic radiography and cone beam computed tomography (CBCT) for implant rehabilitation in a single posterior edentulous space. Methods: This is a crosssectional study of economic analysis nested within a clinical trial carried out by the Nucleus for Research and Prosthesis and Implant (NPPI). Participants were recruited through non-probabilistic convenience sampling and asked about the amount they are willing to pay for each of the exams. Sociodemographic information was collected. Data were analyzed descriptively and through bivariate tests. Results: Forty individuals participated in the study. The median DBH values for panoramic radiography and CBCT were R$ 75.00 (minimum-maximum 0.0 – 150.00) and R$ 300.00 (0.0 – 500.00), respectively. There was no significant difference in DAP when comparing the values between the categories of sociodemographic variables, perception of oral health, dental concern (p<0.05). The correlation between the participant's income and DBH by panoramic radiography (rho 0.091, p=0.575) and by CBCT (rho -0.014, p=0.929) were not statistically significant. Conclusion: The socioeconomic factors studied did not influence the participants' DBH values for panoramic radiography for CBCT. DBH variability by CBCT was greater than DAP variability by panoramic radiography. Studies of PAD by imaging exams are needed to provide scientific evidence about the patient's perception of the costs of these exams and to guide clinical practice.
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    Avaliação salivar do perfil imune-inflamatório do líquen plano oral e sua relação com parâmetros clínicos de severidade da doença: estudo caso - controle
    (Universidade Federal de Goiás, 2025-03-11) Flores, Dryele Ferreira; Mendonça, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847; Arantes, Diego Antônio Costa; http://lattes.cnpq.br/8341286790648954; Arantes, Diego Antônio Costa; Freitas, Gileade Pereira; Mosconi, Carla
    INTRODUCTION: Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory disease of autoimmune nature, which can present in various clinical forms. Although its etiology and clinical behavior are uncertain, studies have highlighted a potential relationship between its pathogenesis and severity with the salivary concentration of mediators involved in the inflammatory process. OBJECTIVE: To evaluate the salivary concentration of pro-inflammatory and anti-inflammatory mediators in patients diagnosed with clinical and microscopic OLP and healthy controls. METHODOLOGY: A case-control study was conducted to investigate the salivary immune-inflammatory profile of patients diagnosed with clinical and microscopic OLP (case group; n=31), according to the criteria established by the American Academy of Oral and Maxillofacial Pathology (AAPOM/2016), and healthy individuals (control group; n=23). All patients were clinically evaluated to record clinical, demographic, and pathological data, as well as for unstimulated saliva collection. Regarding the clinical manifestation, OLP patients were categorized into severe cases (erosive/ulcerated clinical pattern; symptomatic) and non-severe cases (reticular and plaque; asymptomatic). Pro-inflammatory cytokines IL-1, IL-2, IL-6, IL-8, IL-17, IFN-γ, TNF-α, and anti-inflammatory cytokines IL-4 and IL-10 were measured by Cytometric Bead Array (CBA). Mediators associated with oxidative stress (nitrite and MPO) were quantified using the Griess colorimetric method. RESULTS: OLP patients were predominantly female (93.5%) and Caucasian (58.0%). Regarding disease severity, 13 (n=42%) patients were classified as severe cases. The salivary concentration of IL-6, IL-10, and nitrite was significantly higher in OLP patients compared to the control group (p<0.05). Moreover, although not statistically significant, the mean concentrations of IL-17, IL-2, IL-4, and MPO were higher in severe disease cases. Patients with OLP associated with moderate or severe pain exhibited significantly higher nitrite levels compared to controls (p<0.05). CONCLUSION: Salivary levels of the pro-inflammatory mediators IL-6 and nitrite, and the anti-inflammatory cytokine IL-10 were higher in patients with Lichen Planus Oral (LPO) compared to healthy individuals. Furthermore, the salivary concentration of nitrite was higher in LPO cases with greater pain scores. The presence of elevated nitrite levels in saliva may help determine the intensity of symptoms, such as pain and discomfort, which directly affect the well-being and functional capacity of patients. Therefore, monitoring salivary nitrite levels can be crucial for assessing the severity of the disease and, consequently, adapting therapeutic strategies to improve the quality of life of patients with LPO.
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    Avaliação da segurança e eficácia da terapia fotodinâmica com pirulito de azul de metileno comparada a nistatina para o tratamento da estomatite protética: ensaio clínico randomizado duplo cego
    (Universidade Federal de Goiás, 2025-03-06) Mualeite, Egon Bernardo; Costa, Nádia do Lago; http://lattes.cnpq.br/9120865567187887; Costa , Nádia do Lago; Nogueira , Túlio Eduardo; Moreira, Francine do Couto Lima
    Embargada.
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    O serviço de saúde bucal na atenção primária à saúde no município de Goiânia-GO: estudo transversal dos fatores associados à utilização e à satisfação na perspectiva dos usuários
    (Universidade Federal de Goiás, 2024-03-04) Anjos, Gabriela Montenegro dos; Jordão, Lidia Moraes Ribeiro; http://lattes.cnpq.br/8872679253627903; Jordão, Lidia Moraes Ribeiro; França, Mary Anne de Souza Alves; Nogueira, Túlio Eduardo
    Conteúdo embargado
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    Influência do nível de experiência do operador na precisão do acesso endodôntico guiado em dentes com canais calcificados: uma revisão de escopo
    (Universidade Federal de Goiás, 2024-10-31) Deus, Lara Borges de; Silva, Julio Almeida; http://lattes.cnpq.br/1022830186974104; Decurcio, Daniel de Almeida; http://lattes.cnpq.br/4640062828556657; Decurcio, Daniel de Almeida; Silva, Julio Almeida; González, Álvaro Cruz; Siqueira, Patrícia Correia de
    Introduction: Performing conventional endodontic access in teeth with root canal calcification is challenging due to the difficulty in locating and accessing the root canals. This approach can be time-consuming and may pose risks of excessive loss of dental structure, deviations, and even perforations. Guided endodontics emerges as an alternative technique that can facilitate access to the root canal system in teeth with calcifications. Objective: This scoping review aimed to assess the influence of the operator's level of experience on the accuracy of guided endodontic access in teeth with calcified canals. Methodology: The review involved searches in eight electronic databases until August 04, 2024, resulting in the initial identification of 999 records. After removing duplicates and selecting based on titles and abstracts, 31 articles were selected for full-text reading and analysis against the eligibility criteria. Included studies were published between 2019 and 2024 and addressed the influence of operator experience on guided endodontic access. Study evaluation included extracting the following data: study characteristics, objectives, employed methodologies, degree of tooth calcification, operator experience, planning and fabrication of access guides via 3D printing, and instruments used for access. Results: Analysis of the studies revealed significant heterogeneity regarding the models of guides used for guided endodontic access, operator experience, and evaluated parameters (deviation, canal location, wear, and time spent for guided access). However, despite this variability, none of the studies demonstrated a significant influence of operator experience on the accuracy of access guides in teeth with calcified canals. Conclusion: The guided endodontic technique can be a precise and predictable option regardless of the operator’s level of experience, provided it is properly planned and executed.