Effects of energy drinks on mental health and academic performance of university students: a systematic review and meta-analysis protocol
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Objectives
Energy drink (ED) consumption is frequently observed among higher education students
and is often associated with increased concentration and academic performance. However,
the purported benefits are not fully supported by scientific evidence. This protocol
details methods for a systematic review and meta-analysis to evaluate the effects of ED on
university students’ mental health and academic performance.
Methods
The PECO framework will guide the search strategy, and the protocol will follow the
PRISMA-P
2015, PRESS 2015, and PRISMA-S guidelines. The searches will be conducted
in the following databases: Web of Science, Scopus, Ovid, PubMed, Embase,
FSTA, CINAHL, and SPORTDiscus. The GRADE recommendations and the Downs and
Black scale will assess study quality and bias. All statistical analyses will be conducted
using Comprehensive Meta-analysis software. We will use Cochran’s Q with p < 0.05 to
indicate significant heterogeneity and I² to quantify heterogeneity between studies. The
Trim and Fill technique and Egger’s regression test will be applied to evaluate the funnel
plot that will be generated.
Results
Carrying out the systematic review proposed by this protocol will provide evidence on the
short-, medium-, and long-term effects of ED use on academic performance and mental
health among higher education students. Conclusion
A deeper understanding of ED consumption among higher education students can inform
the development of evidence-based educational and public health policies to promote
student well-being and mitigate associated health risks.
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BATISTA, Danyla Rafaela Oliveira et al. Effects of energy drinks on mental health and academic performance of university students: a systematic review and meta-analysis protocol. Plos One, San Francisco, v. 20, e0319533, 2025. DOI: 10.1371/journal.pone.0319533. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0319533. Acesso em: 3 jul. 2026.