FANUT - Artigos publicados em periódicos

URI Permanente para esta coleçãohttp://200.137.215.59//handle/ri/1319

Navegar

Agora exibindo 1 - 20 de 108

Inequalities in the community food environment around Brazilian households with children under 5 years from a national survey in Brazil
(2025) Castro, Inês Rugani Ribeiro de; Schincaglia, Raquel Machado; Leite, Maria Alvim; Lacerda, Elisa Maria de Aquino; Costa, Paula Normando dos Reis; Reis, Neilane Bertoni dos; Kac, Gilberto
This study characterizes the community food environment around households in Brazil with children < 5 years of age and analyzes its association with socioeconomic and demographic stratifiers. Data from 12,524 households from the Brazilian National Survey on Child Nutrition (ENANI-2019) were used. The community food environment was assessed through the perception of mothers or caregivers using three indicators: fruit and vegetable score (FV-S), ultra-processed foods score (UPF-S), and community food environment healthiness score (CFEH-S), all ranging from 0–10 points, categorized as low (worse), medium, and high (better). Unadjusted and adjusted multinomial logistic regression analyses were conducted to determine the independent associations between macro-region, household location, race/skin color, level of education of the mother or caregiver, and basic sanitation, and FV-S, UPF-S, and CFEH-S. The frequency of low and high categories was 21.8% and 64.1% for FV-S, 74.3% and 7.7% for UPF-S, and 34.1% and 9.8% for CFEH-S. Adjusted regressions showed that the North macro-region had the worst scenario for FV-S and CFEH-S. For UPF-S, the Northeast and South regions had the worst scenarios. Despite worse FV-S, rural households had better UPF-S and CFEH-S. Households with 0 or 1 basic sanitation service (sewage system, potable water, or garbage collection) had worse FV-S scores; those with 1 service had the worst CFEH-S scenario. We found that macro-region, place of residence, and access to sanitation services are associated with the healthiness of the community food environment around households with children < 5 years in Brazil.
Serum metabolome indicators of early childhood development in the Brazilian National Survey on Child Nutrition (ENANI-2019)
(2025) Padilha, Marina; Keller, Victor Nahuel Felix de Souza; Costa, Paula Normando dos Reis; Schincaglia, Raquel Machado; Costa, Nathalia Cristina Freitas; Freire, Samary da Silva Rosa; Delpino, Felipe Mendes; Castro, Inês Rugani Ribeiro de; Lacerda, Elisa Maria de Aquino
Background: The role of circulating metabolites on child development is understudied. We investigated associations between children’s serum metabolome and early childhood development (ECD). Methods: Untargeted metabolomics was performed on serum samples of 5004 children aged 6–59 months, a subset of participants from the Brazilian National Survey on Child Nutrition (ENANI2019). ECD was assessed using the Survey of Well-being of Young Children’s milestones questionnaire. The graded response model was used to estimate developmental age. Developmental quotient (DQ) was calculated as the developmental age divided by chronological age. Partial least square regression selected metabolites with a variable importance projection ≥1. The interaction between significant metabolites and the child’s age was tested. Results: Twenty-eight top-ranked metabolites were included in linear regression models adjusted for the child’s nutritional status, diet quality, and infant age. Cresol sulfate (β=–0.07; adjusted-p <0.001), hippuric acid (β=–0.06; adjusted-p <0.001), phenylacetylglutamine (β=–0.06; adjusted-p <0.001), and trimethylamine-N-oxide (β=–0.05; adjusted-p=0.002) showed inverse associations with DQ. We observed opposite directions in the association of DQ for creatinine (for children aged –1 SD: β=– 0.05; pP=0.01;+1 SD: β=0.05; p=0.02) and methylhistidine (–1 SD: β = - 0.04; p=0.04;+1 SD: β=0.04; p=0.03). Conclusions: Serum biomarkers, including dietary and microbial-derived metabolites involved in the gut-brain axis, may potentially be used to track children at risk for developmental delays. Funding: Supported by the Brazilian Ministry of Health and the Brazilian National Research Council.
Prevalence and determinants of wasting and overweight in Brazilian children between 6 and 59 months: Brazilian National Survey on Child Nutrition (ENANI-2019)
(2025) Farias, Dayana Rodrigues; Anjos, Luiz Antonio dos; Berti, Talita Lelis; Santos, Nadya Helena Alves dos; Andrade, Pedro Gomes; Freitas, Maiara Brusco de; Costa, Jaqueline Lepsch da; Oliveira, Natália; Lacerda, Elisa Maria de Aquino; Carneiro, Letícia Barroso Vertulli
Understanding the determinants of malnutrition is pivotal for public health interventions. This study aimed to identify socio-economic, demographic, dietary and maternal determinants of wasting and overweight among Brazilian children between 6 and 59 months. Data from the Brazilian National Survey on Child Nutrition were analysed (n 11 789). Children’s weight-for-height Z-scores were calculated according to the WHO growth standard and classified as wasting (Z < −2), normal weight (–2 ≤ Z ≤ 1), overweight risk (1 < Z ≤ 2) and overweight (Z > 2). Socio-economic, demographic, dietary and maternal covariables were considered. Adjusted multinomial logistic regression (OR and 95 % CI) was employed. The prevalence of overweight and wasting was 9·5 and 2·6 %, respectively. In the adjusted model, younger age (6–23 months: OR: 1·7; 95 % CI: 1·3, 2·2), consumption of ≥ 5 ultra-processed food groups (OR: 1·8; 95 % CI: 1·1, 3·1), maternal underweight (OR: 0·4; 95 % CI: 0·2, 0·9), overweight (OR: 1·5; 95 % CI: 1·2, 1·9) and mild food insecurity (OR: 0·8; 95 % CI: 0·6, 1·0) were associated with child overweight. The Brazilian Northeast (OR: 4·9; 95 % CI: 2·1, 11·3), Southeast (OR: 7·1; 95 % CI: 3·0, 16·6), South (OR: 4·7; 95 % CI: 1·8, 12·1), Midwest regions (OR: 2·7; 95 % CI: 1·2, 6·2) and maternal underweight (OR: 5·4; 95 % CI: 2·7, 10·7) were associated with wasting. Overweight in Brazil is prevalent among children between 6 and 59 months, while wasting is not a major public health problem. The main determinants of these Brazilian children’s nutritional status were age, ultra-processed food consumption and maternal nutritional status.
Maternal schooling and child's age interaction and its association with ultra-processed food consumption in Brazilian children <5 years of age: results from the Brazilian National Survey on Child Nutrition (ENANI-2019)
(2025) Mello, Juliana Vieira de Castro; Schincaglia, Raquel Machado; Andrade, Pedro Gomes; Santos, Nadya Helena Alves dos; Farias, Dayana Rodrigues; Oliveira, Natália; Lacerda, Elisa Maria de Aquino; Carneiro, Letícia Barroso Vertulli; Costa, Paula Normando dos Reis; Castro, Inês Rugani Ribeiro de
Background The consumption of ultra-processed foods (UPFs) has increased worldwide, including among children. Maternal schooling has been associated with children's UPF consumption. The present study examined the interaction between maternal schooling and child age in the association with UPF consumption in Brazilian children <5 years. Methods The Brazilian National Survey on Child Nutrition (ENANI-2019) is a household-based population survey of 14,558 children <5 years residing in 123 Brazilian municipalities. A structured questionnaire was used to quantify the consumption of nine groups of UPF, according to the NOVA classification, on the day before the interview. The mean, standard deviation and 95% CI for UPF consumption are presented. A multiple Poisson regression model was used, including an interaction between maternal schooling and child age, to estimate the predicted consumption of UPF. Results The prevalence of consumption of at least one UPF group was 81% in Brazilian children <5 years, with the most consumed UPFs being sweet or savoury biscuits/cookies (51.0%), sweetened beverages (37.5%), baby cereals (29.4%) and yogurt (28.1%). Children 6–11 months of age had a lower mean consumption of UPF when maternal schooling was >12 years (0.73 [95% CI: 0.48–0.98]) compared to those whose mothers had ≤7 years (1.55 [95% CI: 1.18–1.92]) and 8–11 years of schooling (1.40 [95% CI: 1.19–1.61]). The interaction model between maternal schooling and child age (p < 0.001) indicated that children of mothers with higher schooling had significantly lower consumption of UPF up to 8 months of age. However, no significant differences in consumption were observed thereafter. Conclusions The child age modifies the association of maternal schooling on UPF consumption, that is, UPF consumption was lower for children up to 8 months when their mothers had higher schooling, whereas no significant results were found for older infants.
Energy and nutrient intake across Nova food groups by quintiles of ultra-processed food energy contribution among Brazilian children aged 6–59 months
(2026) Oliveira, Natália; Schincaglia, Raquel Machado; Carneiro, Letícia Barroso Vertulli; Lacerda, Elisa Maria de Aquino; Crispim, Sandra Patrícia; Berti, Talita Lelis; Santos, Isabel N. dos; Costa, Jaqueline Lepsch da; Farias, Dayana Rodrigues; Santos, Nadya Helena Alves
The objective is to describe energy, macro- and micronutrient intake according to Nova food groups and to estimate its association with ultra-processed foods (UPF) energy participation in the diets of children, stratified by age (6–23 m/24–59 m). A single 24-h recall from 12 553 children in the Brazilian National Survey on Child Nutrition was used to estimate the relative energy contribution of Nova groups: unprocessed or minimally processed foods and culinary ingredients (G1 + G2); processed foods (G3) and UPF (G4). Age-stratified linear regression and 95 % CI assessed differences in nutrient intake (per 1000 kcal) across UPF energy quintiles. The G1 + G2 group accounted for most of the energy consumed (6–23 m: 74·5 %; 24–59 m: 65·1 %) compared with G3 or G4. For both age groups, in the lowest quintile of UFP participation, ≤ 2 % of energy came from UPF, while in the highest quintile, this proportion was > 55 % and the G1 + G2 group provided most nutrients. In 6–23 m, higher UPF quintiles were associated with lower fat (β: –3·1 (–3·6, –2·5)), potassium (β: –49·7 (–67·9, –31·4)) and vitamin A RAE (β: –113·7 (–136·7, –90·6)) intake, but higher Ca ((β: 75·5 (57·6, 93·4)), Fe (β: 2·9 (2·5, 3·3)), vitamin A RE (β: 104·3 (72·3, 136·3)) and folate (β: 15·7 (12·0, 19·5)) intake. In 24–59 m, nutrient intake generally decreased with increasing UPF quintiles. For 6–23 m/24–59 m, UPF consumption was positively associated with energy (β: 73·6 (44·6, 102·7); 92·8 (66·7, 118·8), respectively) and carbohydrate (β: 7·3 (5·8, 8·7); 2·3 (1·2, 3·3), respectively), while contributing little to overall micronutrient intake.
Food insecurity, anemia and vitamin a deficiency in Brazilian children aged between 6 and 59 months of age: Brazilian National Survey on Child Nutrition (ENANI-2019)
(2025) Silva, Letícia Ramos da; Costa, Paula Normando dos Reis; Schincaglia, Raquel Machado; Castro, Inês Rugani Ribeiro de; Andrade, Pedro Gomes; Berti, Talita Lelis; Lacerda, Elisa Maria de Aquino; Santos, Nadya Helena Alves dos; Carneiro, Letícia Barroso Vertulli; Kac, Gilberto
Background: Anemia and vitamin A deficiency (VAD) can be related to poverty and food insecurity (FI), which can increase risk of stunting and delayed child development. Objectives: This study aims to assess the association between FI and the occurrence of anemia and VAD in Brazilian children aged 6–59 months. Methods: Data from 6020 children from the Brazilian National Survey on Child Nutrition (2019) were used. FI was assessed using the Brazilian Food Insecurity Scale, classifying households into food security (FS) and FI levels. The outcomes were anemia [hemoglobin <10.5 g/dL (6–23 months) and hemoglobin <11 g/dL (24–59 months)] and VAD (retinol corrected by C-reactive protein <0.7 μmol/L). FI frequencies, anemia, and VAD prevalences were calculated according to FI levels, 95% confidence intervals (CIs), and P-trend. The adjusted prevalence ratio (PR) was estimated using quasi-Poisson regression. Results: The prevalence of mild, moderate, and severe FI was 37.7% (95% CI: 32.0%, 43.4%), 6.2% (95% CI: 4.8%, 7.6%), and 4.2% (95% CI: 3.1%, 5.3%), respectively. The prevalence of anemia was 7.1% (95% CI: 5.9%, 8.3%), and VAD was 3.0% (95% CI: 2.5%, 3.6%). A significant linear trend (P-trend < 0.001) was observed in the prevalence of anemia according to the degree of FI: severe (15.5%; 95% CI: 8.1%, 22.9%), moderate (10.0%; 95% CI: 5.4%, 14.6%), mild (6.6%; 95% CI: 4.9%, 8.3%), and FS (6.4%; 95% CI: 4.7%, 8.1%). Childrenliving in households with severe FI had an 82% higher prevalence of anemia (PR: 1.82; 95% CI: 1.40, 4.17) than those living in FS. A significant linear trend (P-trend< 0.001) was observed in the prevalence of VAD according to the degree of FI: severe (3.3%; 95% CI: 0.0%, 6.7%), moderate (5.8%; 95% CI: 2.3%, 9.2%), FI (2.8%; 95% CI: 1.9%, 3.7%), and FS (2.9%; 95% CI: 2.1%, 3.7%). No association was observed between FI and VAD. Conclusions: Severe FI was associated with anemia among Brazilian children aged 6–59 months.
Prebiotic potential of pulp and by-products from native fruits of the Brazilian savannah
(2025) Oliveira, Deborah Dias; Souza, Luciana Conrado Duarte de; Barbosa, Jéssica Pereira; Silva, Bibiana da; Costa, Ana Carolina de Oliveira; Purgatto, Eduardo; Gonçalves, José Eduardo; Souza, Patrícia Amaral
Native fruits from the Brazilian Savannah, such as jatobá-do-Cerrado (Hymenaea stigonocarpa) and jenipapo (Genipa americana L.), have interesting sensory and nutritional qualities. Jatobá-do-Cerrado consumption is limited due to its aroma and texture. Jenipapo is widely used in food and cosmetics, though its by-products (peel and seeds) are often discarded. The present study evaluates the nutritional aspects (proximate composition, antioxidant capacity, phenolic compounds, and prebiotic potential) as well as the technological properties (water and oil holding capacity) of the jatobá-do-Cerrado pulp (JAP) and the jenipapo by-product (JEBP). JAP and JEBP exhibited high dietary fiber content, mainly insoluble fiber, as well as a high concentration of phenolic compounds and antioxidant activity superior to other Cerrado fruits. JAP and JEBP showed WHC of 3.16 and 4.06 g/g and OHC of 3.09 and 1.14 g/g, respectively, indicating their potential for food processing and product development. Fermentation tests showed that JAP and JEBP supported probiotic (Lactobacillus and Bifidobacterium) growth similarly to fructooligosaccharides (FOS), lowering the medium’s pH. Fermentation also stimulated the synthesis of bioactive amines such as spermidine and phenylethylamine. Thus, they are promising prebiotic ingredients for functional foods and supplements.
Probiotic potential and functional evaluation of Pediococcus acidilactici and Lactiplantibacillus plantarum from Cerrado fruit by-products in mangaba-fermented beverage
(2025) Barbosa, Jéssica Pereira; Martins, Eliane Maurício Furtado; Lima, Marcos dos Santos; Souza, Patrícia Amaral
Cerrado fruit-fermented beverages enriched with potential probiotics strains derived from vegetal matrices present a promising alternative for individuals who avoid dairy products. However, identifying suitable probiotic strains poses a critical challenge. This study aims to characterize three potential probiotic strains isolated from Cerrado fruit by-products based on their safety, technological, and functional properties. Subsequently, the fermentation of mangaba (Hancornia speciosa Gomes) beverage with the potential probiotic strains was investigated, by evaluating its microbiological, physicochemical, and functional features. The strains exhibited high auto-aggregation and cell surface hydrophobicity (>53 % and >59 %, respectively), antifungal activity, resistance to simulated gastrointestinal conditions and freeze-dried process (without log reductions and survival rates between 0.96 ± 0.06 and 1.03 ± 0.04). Mangaba beverage can be used as an ideal non-dairy matrix for fermentation by the potentially probiotic freeze-dried strains Pediococcus acidilactici M7, Pediococcus acidilactici P2 and Lactiplantibacillus plantarum 9, individually. P. acidilactici P2 and L. plantarum 9, demonstrated robust viability and fermentation capabilities throughout the 35-day storage period at 4 °C, ensuring the preservation of viable cell counts, production of phenolic compounds (3.69 ± 0.02 mg/L of epigallocatechin gallate) and organic acids (1.30 ± 0.00 g/L of lactic acid). Mangaba beverage served as an ideal non-dairy matrix for fermentation by the potentially probiotic freeze-dried strains, which aids in the recognition of native Cerrado Savannah fruits by-products, contributing to the valorization of the biome.
Cerrado fruits residues under probiotic strains fermentation: prebiotic properties and polyamine production
(2025) Oliveira, Julia Graciela Plaza de; Barbosa, Jéssica Pereira; Costa, Ana Carolina de Oliveira; Purgatto, Eduardo; Gonçalves, José Eduardo; Souza, Patrícia Amaral; Silva, Bibiana da
Background. Limited information exists on the chemical composition and prebiotic properties of cajuzinho- -do-cerrado (Anacardium humile) and marmelo-do-cerrado (Alibertia sessilis) residues, which are typically discarded during fruit processing. This study characterizes these residues and investigates their prebiotic potential. Material and methods. The antioxidant capacity, phenolic compounds, functional properties, and prebiotic potential of the residues were evaluated. Methanolic extracts were analyzed using spectrophotometric methods (DPPH, Folin-Ciocalteu) and HPLC. Water and oil holding capacities were measured by centrifugation. Three probiotic strains and two E. coli strains were cultivated in modified media using the residues as carbon sources. Cell viability was assessed by agar plate counts. Metabolic activity was monitored by measuring pH, sugar and organic acid concentrations, and bioactive amine production using HPLC. These analyses were designed to evaluate functional characteristics of the residues, including antioxidant capacity, water and oil holding abilities, and their ability to support probiotic growth and metabolism, thereby assessing prebiotic potential. Results. CR and MR showed high levels of total dietary fiber and protein. Considerable concentrations of total phenolic compounds were detected; gallic acid and coniferaldehyde were quantified in CR, while p-coumaric acid and luteolin were quantified in MR. Cultivation of Lactobacillus acidophilus LA-05, Lacticaseibacillus casei L-26, and Bifidobacterium animalis subsp. lactis BB-12 in media containing CR and MR promoted their growth – especially L. casei – along with a decrease in pH and significant production of organic acids, such as lactic and acetic acids. Fermentation of these residues also led to polyamine production, including spermidine, indicating intense fermentative metabolic activity by these microorganisms. Conclusion. The residues display characteristics indicative of prebiotic potential and may confer human health benefits. They could also be considered as functional ingredients for the formulation of new food products.
An overview of Beriberi
(2025) Pereira, Amanda Gomes; Cunha, Letycia Netto de Paula; Paiva, Sergio Alberto Rupp de; Gaiolla, Paula Schmidt Azevedo; Zornoff, Leonardo Antônio Mamede; Polegato, Bertha Furlan; Costa, Nara Aline; Minicucci, Marcos Ferreira
Beriberi is a nutritional disorder caused by thiamine deficiency. Classically, Beriberi presents in two primary clinical forms: “wet” Beriberi, which features heart and circulatory system impairment, and “dry” Beriberi, which causes polyneuropathy. Although it is an easily treatable condition, it is often misdiagnosed and can be lifethreatening if not promptly recognized and managed. The diagnosis of Beriberi is performed by the signs and symptoms of the disease and can be confirmed by thiamine deficiency identification or by therapeutic testing. However, considering the costs and the limitations of the assays to evaluate thiamine deficiency, the diagnosis based on the evaluation of clinical signs and symptoms and the therapeutic test could eliminate the need for measuring serum thiamine levels. Regarding treatment, immediate thiamine administration in the presence of clinical manifestations of the disease is recommended. Overall, 100–300 mg daily doses are enough to improve symptoms. In this review, we aim to (1) provide a clinical update about how to identify and treat the Beriberi and (2) describe the historical perspective, pathophysiological mechanisms, and other relevant aspects which may have applications in clinical management of Beriberi
Low physical function is a risk factor for mortality in non-dialysis-dependent chronic kidney disease patients
(2025) Rodrigues, Hellen Christina Neves; Sousa, Amanda Goulart de Oliveira; Preto, Vitória Rodrigues Morais; Cunha, Letycia Netto de Paula; Oliveira, Samara Vieira de; Santos, Mariana Ferreira dos; Costa, Nara Aline
The progression of chronic kidney disease (CKD) is associated with functional impairment [1, 2]. However, little is known about the impact of compromised physical function on health outcomes in patients with CKD without need for kidney replacement therapy (KRT) [2, 3]. Evaluation of physical function can be used as a screening tool and in the development of intervention protocols that reduce the risks of patient-centered adverse outcomes. Additionally, handgrip strength and gait speed are easy-to-perform and low-cost markers. This study aimed to evaluate whether low physical function is associated with hospitalization and mortality in patients with CKD without need for KRT. This cohort study was conducted prospectively and included patients diagnosed with CKD stages 3b–5 without KRT, age 18–80 years, of both genders, and under regular follow-up in two nephrology outpatient clinics in Goiânia, Goiás, Brazil. CKD stages 3b-5 were confirmed by estimated glomerular filtration rate (eGFR) ≤ 45 mL/min/1.73 m2, using the baseline creatinine value and the CKD Epidemiology Collaboration equation. Patients with the following conditions were excluded: active neoplasia, liver cirrhosis, kidney transplant, pregnancy, limb amputation, or physical walking impairment.
Consumption of ultra-processed foods and its impact on health outcomes in hemodialysis patients: a prospective observational study
(2025) Cunha, Letycia Netto de Paula; Santos, Mariana Ferreira dos; Oliveira, Samara Vieira de; Vieira, Nayane Maria; Preto, Vitória Rodrigues Morais; Schincaglia, Raquel Machado; Minicucci, Marcos Ferreira; Costa, Nara Aline
Aim The present study aims to evaluate the association between the consumption of ultra-processed foods and negative outcomes in hemodialysis (HD) patients. Methods The sample consisted of individuals of both sexes, aged≥18 years. At the time of inclusion in the study, participants responded to information about food consumption. The 24-h food recall was used to estimate food consumption. The Nova classification was adopted for the qualitative evaluation of foods in four groups: in nature, minimally processed, processed and ultra-processed. Patients were followed for 6 months, and the combined outcomes, defined as the occurrence of either hospitalization or mortality from all causes, was assessed. Results Of the 137 hemodialysis patients evaluated, 25.5% presented combined outcomes (hospitalization or all-cause mortality). The consumption of ultra-processed foods was high (82.5%), although the multiple logistic regression analysis did not demonstrate a statistically significant association between the consumption of these foods and the outcomes. The odds ratio (OR) for the consumption of ultra-processed foods was 0.15 (95% CI: 0.00–6.24; p=0.319) in the adjusted model. None of the other food groups, according to the NOVA classification, showed a significant association with the analyzed outcomes. Conclusion Food consumption according to the Nova classification was not associated with outcomes in HD patients. However, it was possible to verify in this population a high consumption of ultra-processed foods, accompanied by low caloric and protein intake.
Sleep hours and late dinner are not associated with combined outcomes in peritoneal dialysis patients
(2025) Pacheco, André Luís Oliveira; Rodrigues, Hellen Christina Neves; Cunha, Letycia Netto Paula; Oliveira, Samara Vieira de; Santos, Mariana Ferreira dos; Costa, Nara Aline
Aim To evaluate the association between late-night dinner and sleep duration with the combined outcomes in peritoneal dialysis (PD) patients. Methods This is a prospective cohort study. Patients undergoing outpatient PD treatment for at least 3 months, aged≥18 years, of both sexes, were included. Demographic, clinical, laboratory, and anthropometric data were collected. Late-night dinner was defined as the habit of eating up to 2 h before bed at least three times a week. The average time in hours of sleep was recorded on 3 days of the week. The patients were followed for 6 months, and the outcomes were the occurrence of hospital admission and peritonitis during the period. Data was expressed as mean and standard deviation or median and interquartile range or absolute (n) and relative (%) values. The significance level adopted was 5%. Results Included 49 patients; 53.1% were women and the mean age of 60.7±16.1 years. Around 32.7% of patients had a late-night dinner habit. The average sleep time was 8.6±2.1 h and 36.7% of patients had combined outcomes. Furthermore, the prevalence of malnutrition was higher in the group of patients with combined outcomes. Patients with hours of sleep<6 and≥9 h were more malnourished according to 7-point Subjective Global Assessment (SGA-7p). No association was found between hours of sleep and late-night dinner with combined outcomes. Conclusion No significant association was found between sleep hours and late-night dinner and the development of outcomes. However, due to the short period of follow-up, more studies are needed.
Water-soluble pequi almond extract: a novel probiotic and sustainable beverage
(2025) Barbosa, Jéssica Pereira; Damasceno, Renatta Pereira Barbosa; Balthazar, Lívia Fatorelli; Monteiro, Bruna de Oliveira; Lima, Naiadhe Carvalho; Souza, Patrícia Amaral
Introduction: The edible pulp of pequi (Caryocar brasiliense Cambess.) is the most valued component of the fruit and is used for human consumption. However, when into food, a significant amount of waste is produced and could impact the environment. Therefore, reusing these byproducts, such as pequi almonds, as an alternative for new product development is a proposal for sustainable consumption. Adding probiotic microorganisms isolated from plant matrices, such as byproducts cerrado fruits, makes it an even more sustainable and accessible option for the vegan population. Objective: The present study aimed to characterize the pequi almond extract supplemented with potentially probiotic microorganisms (Lactiplantibacillus plantarum/pentosus M3 and M1), isolated from cerrado fruit by-products, as a fermented beverage. Methods: The effects of fermentation on viable cell counts and physicochemical properties such as pH, soluble solids, and color were assessed on the day of processing before fermentation, after fermentation, after 7 days, and 14 days during storage of the preparation at 8°C. Results and Discussion: The counts of potentially probiotic cultures M1 and M3 showed an inverse correlation with the sample pH, indicating greater bacterial adaptation. The higher survival of strains in water-soluble pequi almond extract (WSPAE) may be associated with the isolation matrix being part of the same matrix to which they were added. No differences were observed in the total soluble solids and color of the preparations added with M1 and M3. Conclusion: WSPAE demonstrated protective effects for the maintenance and survival of the tested strains. These findings support the potential use of these strains in plant-based probiotic beverages as a sustainable alternative to dairy products.
Frailty scale with the best prediction of mortality in individuals diagnosed with acute coronary syndrome: systematic review and meta-analysis
(2026) Cunha, Letycia Netto de Paula; Oliveira, Samara Vieira de; Silva, Taline Alisson Artemis Lazzarin; Silva, Lara Lívia Santos da; Minicucci, Marcos Ferreira; Costa, Nara Aline
Background Acute Coronary Syndrome (ACS) is a major cause of hospitalizations and deaths worldwide. Conditions such as frailty worsen these outcomes. Frailty assessment improves risk stratification, complements scores and favors personalized treatments. However, there are numerous tools available for assessing frailty, and there is still no consensus on which would be the most recommended in conditions such as ACS. The objective was to evaluate which frailty diagnostic scale has the best predictive value for mortality in individuals with ACS. Methods This meta-analysis was conducted using Medline, Embase, and Cochrane, with a search conducted on March 5, 2024. Studies that met the PECOS criteria were included: adult and elderly individuals diagnosed with ACS, frailty assessment determined by a scale, mortality registry and intervention studies or prospective and retrospective cohorts. The risk of bias and quality of evidence were assessed by two researchers using the Joana Briggs Institute Case Series tool and the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) system, respectively. The meta-analysis was conducted using Review Manager software and subgroup analyses using R software. Results The results of the meta-analysis indicate that frailty is associated with a significantly higher risk of mortality in patients with ACS (P < 0.001). However, the results of the meta-regression did not indicate a significant difference between the five scales evaluated (P = 0.227). The choice of scale, therefore, can be based on other factors such as practicality and availability of resources, without compromising the prognosis. Conclusion Individuals with ACS and frailty have a higher chance of mortality, and all scales evaluated showed good predictive value, with no statistical difference. We suggest that the Clinical Frailty Scale (CFS) is suitable for hospital settings and acute conditions, such as ACS.
Lower preoperative functional capacity and frailty result in longer mechanical ventilation time and hospital stay in individuals undergoing cardiac surgery
(2025) Dourado, Thais Lima; Cunha, Letycia Netto de Paula; Rosa, Daniel de Oliveira; Alkas, Pedro Gabriel de Carvalho; Elmiro, Gustavo Siqueira; Loyola, Stanlley de Oliveira; Martins, Geise Rodrigues; Souza, Artur Henrique de; Costa, Nara Aline; Gardenghi, Giulliano
Peritoneal dialysis influences microRNA expression and pro-inflammatory response: results from a cross-sectional study
(2026) Costa, Nara Aline; Pereira, Amanda Gomes; Rodrigues, Hellen Christina Neves; Cuppari, Lilian; Felix, Tainara Francini; Minutentag, Iael Weissberg; Reis, Patricia Pintor dos; Balbi, André Luis; Polegato, Bertha Furlan; Gaiolla, Paula Schmidt Azevedo
First dual-frame telephone survey for non-communicable disease risk and protective factors: methods and main findings from a central Brazilian state, 2022
(2026) Carvalho, Magna Maria de; Oliveira, Max Moura de; Oliveira, Selma Alves Tavares de; Peixoto, Maria do Rosario Gondim; Almeida, Roberio Pondé Amorim de; Silva, Flúvia Pereira Amorim da; Siqueira Júnior, João Bosco
Objectives: To Describe the methodology used in the first risk factor survey for non-communicable diseases in Goi´ as, a central state of Brazil and identify differences in prevalence of risk and protective factors for chronic disease between landline and mobile phone users. Study design: A cross-sectional study. Methods: A cross-sectional study was conducted using telephone interviews via landlines and mobile phones. The Random-Digit Dialing probabilistic sampling method was used to select phone lines. The Rake method weighted the data and the hot deck technique imputed missing weight and height data. A total of 5018 individuals residing in Goi´ as were stratified by sex, age group, education level and health macro-regions. Operational, demographic characteristics and prevalence of risk factors were evaluated, with crude and adjusted prevalence ratios calculated using the Poisson regression model. Results: Mobile telephony offered some operational advantages, while refusal rates were lower for landlines. Landline telephony underestimated men, adults and individuals with fewer years of schooling, while mobile's underestimated the elderly. Significant differences in prevalence were found for 16 indicators. Mobile phone users showed higher prevalence of risk factors, while landline's showed higher prevalence of protective factors. Conclusion: The use of both landline and mobile telephony was necessary to ensure population representativeness. However, new strategies are needed to improve participation in future surveys.
Evolução da cobertura do sistema de vigilância alimentar e nutricional em municípios do estado de Goiás que receberam o financiamento federal para ações de alimentação e nutrição entre 2019 e 2023
(2025) Pacheco, André Luís Oliveira; Silva Filho, Emanoel Oliveira; Carvalho, Nágila Araújo de; Vieira, Liana Lima; Moreira, Mariana Martins; Peixoto, Maria do Rosario Gondim
Introduction: Changes in dietary patterns in Brazil, with a 35% increase in the consumption of ultraprocessed foods in recent decades, have contributed to the rise in chronic diseases, making nutritional monitoring essential to guide effective public policies. Objective: To evaluate the evolution of nutritional status and food consumption records of the population of municipalities in Goiás benefiting from federal funding for food and nutrition actions (FAN) between 2019 and 2023. Methodology: Ecological time series study from 2019 to 2023. Data on the nutritional status and food consumption of the population of the municipalities was obtained from information registered in the Food and Nutrition Surveillance System (SISVAN). Results: In 2019, the number of records of nutritional status rose from 374,470 to 1,207,374 in 2023. Food consumption records rose from 8,930 in 2019 to 109,461 in 2023. After a drop in 2020, the data showed a recovery in the following years, with notable advances in 2022 and 2023. The municipality of Novo Gama stood out with a 593-fold increase in food consumption records and a 3.45fold increase in nutritional status, reflecting 7,26% and 36,58% of the population, respectively. Aparecida de Goiânia also showed significant increases, but the records are still low in relation to the total population. Conclusion: There was a greater increase in nutritional status records compared to food consumption records, which indicates an improvement in data records, possibly due to the financial incentive received.
Advancing precision nutrition: bridging mechanistic insight and clinical implementation
(2025) Silva, Bruna Ramos da; Brennan, Lorraine; Horst, Maria Aderuza; Wishart, David Scott; Prado, Carla M.

Navegar

Submissões Recentes