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Synbiotic nutraceutical mitigates gestational diabetes effects and cardiovascular dysfunction in rat offspring
(2025) Lemos, Deborah Emanuelle Cândido de Albuquerque; Souza, Evandro Leite de; Silva, Jaielison Yandro Pereira da; Freire, Micaelle Oliveira de Luna; Costa, Paulo César Trindade da; Cruz, Josiane de Campos; Oliveira, Alisson Macário de; Mota, João Felipe; Alves, José Luiz de Brito
This study investigated the effects of a nutraceutical combining jabuticaba peel (Myrciaria jaboticaba (Vell.) Berg) and Limosilactobacillus fermentum strains on gut microbiota, glycaemic and lipid profiles, and inflammatory markers in rats with gestational diabetes mellitus (GDM), as well as its effects on cardiac autonomic function in the offspring. Pregnant Wistar rats were assigned to control (CTL), GDM, and GDM receiving the nutraceutical (GDM+Nut). The nutraceutical (2 g/kg) or vehicle (PBS) was administered twice daily. After weaning, the offspring were fed laboratory chow until 80 days of age. Nutraceutical administration improved glucose tolerance and reduced serum inflammatory cytokines (TNF-α and IL-6). Beta diversity was increased without altering alpha diversity indices in the GDM+Nut. Nutraceuticals increased the abundance of short-chain fatty acid-producing bacteria. Maternal supplementation protected against autonomic dysfunction in the offspring. Nutraceutical supplementation shows potential as an alternative therapy for the treatment of GDM, while mitigating autonomic dysfunction in offspring.
Association between phase angle from bioelectrical impedance and dietary intake in athletes: a cross-sectional study
(2025) Ravagnani, Christianne de Faria Coelho; Lopes, Lorena Cristina Curado; Godois, Allan da Mata; Silva, Analiza Mónica; Cordeiro, Vitor; Santos, Adolfo Henrique Costa dos; Mota, João Felipe
Phase Angle (PhA) has emerged as an important parameter to monitor body composition, fluid status, muscle integrity, and physical performance among athletes. However, limited information exists regarding the associations between PhA and dietary intake, especially in athletes. This study aimed to identify the dietary intake components associated with PhA in athletes. This cross-sectional observational study was carried out with 153 athletes across 17 sports. Body composition was assessed by tetrapolar multifrequency BIA, and dietary intake by 24-hour dietary recalls administered on non-consecutive days. Reported foods and supplements were categorised into different groups (i.e. cereals, vegetables, fruits, beans and nuts, meat and eggs, dairy products, oils, and sugars), with portions established based on the food’s total energy content. Fat-free mass and fat-free mass index were higher in male compared to female athletes, potentially influencing PhA (6.6º vs 5.5º; P < 0.01). Multiple linear regression analysis indicated that protein intake was a significant predictor of PhA in athletes. This association remained significant even after adjustments for sex, age, and fat-free mass (R2 = 0.48, β = 0.27, P = 0.02). The positive correlation observed between dietary protein and PhA reinforces the need for adequate daily protein intake to enhance PhA in athletes. Further studies investigating the effect of diet-induced changes in PhA within the athletic population are necessary.
Improving muscle function through a multimodal behavioural intervention for knee osteoarthritis and obesity: the POMELO trial
(2025) Godziuk, Kristine; Forhan, Mary; Vieira, Flávio Teixeira; Mota, João Felipe; Werle, Jason; Batsis, John A.; Donini, Lorenzo M.; Siervo, Mario; Prado, Carla M.
Background Treatments aimed at improving physical function and body composition, including reducing fat mass (FM) and increasing muscle mass, may benefit individuals with advanced knee osteoarthritis (OA) and obesity. We investigated the feasibility and efficacy of a multimodal behavioural intervention compared to usual care to enhance physical function and muscle mass in this population. Methods The POMELO (Prevention Of MusclE Loss in Osteoarthritis) study is a two-arm pilot randomized controlled trial; NCT05026385. Participants aged 40–75 years, with a BMI ≥ 35 kg/m2 and knee OA were randomized 1:1 to either the intervention group (POMELO) or usual care (UC). The 3-month POMELO intervention incorporated progressive resistance exercise (3 sessions/week), individualized nutrition counselling targeted for OA, and 12 group education sessions on nutrition and arthritis self-management. The UC group received standard clinical care. After the 3-month supervised intervention, both groups were followed for 6 months without support. Assessments at baseline, 3 months and 9 months (primary endpoint) included body composition (DXA, measuring FM and appendicular lean soft tissue [ALST]), physical function (chair-sit-to-stands [CSTS], 6-min walk [6MWT], maximal handgrip strength [HGS]), and health-related quality of life (Euroqol visual analog scale [EQ-5D VAS]). Co-primary outcomes were feasibility (intervention completion ≥ 80% and per-protocol adherence ≥ 60% [i.e., attendance at 12 education sessions and exercise 3 ×/week]) and acceptability (4-item Likert-scale satisfaction survey, and open-ended questions). Secondary outcomes included changes in physical function and ALST. Results Fifty participants were randomized (POMELO = 25, UC = 25), with 32 completing the study (69% female, mean age 64.9 ± 1.2 years, BMI 42.1 ± 1.0 kg/m2). The POMELO intervention group had 80% completion and 74% adherence, confirming feasibility. Higher satisfaction rates were observed in POMELO compared to UC (3.5 vs. 2.2, p < 0.001) indicating greater acceptability. The POMELO group had improvements in CSTS (mean difference [MD] 3.96, ES 1.2, p < 0.001), 6MWT (MD 31.6 m, ES 0.4, p = 0.039) and EQ-5D VAS (MD 7.9 points, ES = 0.4, p = 0.01) compared to UC. Both groups experienced FM loss, but only the UC group lost ALST and HGS. Conclusion The POMELO intervention, combining personalized nutrition, resistance exercise and self-management support, was feasible, acceptable and showed greater efficacy than usual care to improve physical function in patients with knee OA and obesity. Our pilot study of this intervention showed potential benefits on body composition and quality of life without focusing on weight reduction. A larger study is needed to confirm these results, as this approach may offer advantages over usual care, potentially leading to better mobility and health outcomes.
New insights into total and resting energy expenditure using state-of-the-art methods in cancer survivors: a cross-sectional study
(2025) Pagano, Ana Paula; Mota, João Felipe; Purcel, Sarah A.; Sousa, Iasmin Matias de; Hongyi, Cai; Skipworth, Richard J. E.; Preston, Skipworth Tom; Singer, Pierre; Sawyer, Michael B.; Elango, Rajavel; Walter, Peter J.; Prado, Carla M.
Background: Precise measurement of energy expenditure is essential for guiding nutritional care after cancer treatment. However, commonly used predictive equations may be inaccurate for individuals recovering from cancer. Leveraging state-of-the-art methods can offer valuable insights into the actual energy requirements of cancer survivors upon treatment completion. Objectives: The aim of this study was to characterize total (TEE) and resting energy expenditure (REE) and to assess the accuracy of predictive equations against measured values in posttreatment colorectal cancer survivors (CRCSs). Methods: In this cross-sectional study, 4 TEE and 22 REE equations were compared against doubly labeled water and whole-room indirect calorimeter, respectively. Accuracy was assessed via paired t test, Bland-Altman analysis, and the proportion of predictions within 10% of measured values. Pearson correlations investigated relationships between percentage bias and variables of interest [e.g., age, weight, BMI (in kg/m2), and body composition]. Results: Twenty participants (equal sex distribution; mean ±SD age: 61.4 ±14.1 y; BMI: 28.8 ±6.4) were included. Most had a history of colon cancer (55%) and stage III disease (75%). Predictive equations (predicted TEE range: ~2060–2500 kcal/d; predicted REE range: ~1230–1730 kcal/d) commonly underestimated measured TEE (~2460 ±680 kcal/d) (n =2, 50%) and REE (~1700 ±330 kcal/d) (n =19, 86.4%). Dietary Reference Intake equations with estimated physical activity level had the highest individual-level accuracy for TEE prediction but still resulted in substantial intra- individual variability (~≤1400 kcal error). BMI and body composition were positively related to percentage bias in TEE but not REE equations. For REE, the Johnstone and Harris-Benedict equations showed the best individual-level agreement but still exhibited high intraindividual variability, with errors up to ~≤460 kcal and ~≤530 kcal, respectively. Conclusions: The majority of CRCSs exhibit higher energy expenditure than estimated by standard prediction equations, underscoring the need to validate these equations in populations with cancer to optimize accuracy. Improved methods for assessing energy expenditure are needed to guide long- term survivorship care
Cardiometabolic benefits of a non-industrialized-type diet are linked to gut microbiome modulation
(2025) Fuyong, Li; Armet, Anissa M.; Korpela, Katri; Liu, Junhong; Quevedo, Rodrigo Margain; Asnicar, Francesco; Seethaler, Benjamin; Rusnak, Tianna B. S.; Cole, Janis L.; Zhihong, Zhang; Mota, João Felipe
Industrialization adversely affects the gut microbiome and predisposes individuals to chronic non-communicable diseases. We tested a microbiome restoration strategy comprising a diet that recapitulated key characteristics of non-industrialized dietary patterns (restore diet) and a bacterium rarely found in industrialized microbiomes (Limosilactobacillus reuteri) in a randomized controlled feeding trial in healthy Canadian adults. The restore diet, despite reducing gut microbiome diversity, enhanced the persistence of L. reuteri strain from rural Papua New Guinea (PB-W1) and redressed several microbiome features altered by industrialization. The diet also beneficially altered microbiota-derived plasma metabolites implicated in the etiology of chronic non-communicable diseases. Considerable cardiometabolic benefits were observed independently of L. reuteri administration, several of which could be accurately predicted by baseline and diet-responsive microbiome features. The findings suggest that a dietary intervention targeted toward restoring the gut microbiome can improve host-microbiome interactions that likely underpin chronic pathologies, which can guide dietary recommendations and the development of therapeutic and nutritional strategies.
Optimizing dietary fiber intake: strategies for human nutrition and food science
(2026) Walsh, Sarah Kate; Armet, Anissa M.; Nikolaeva, Daria D.; Mota, João Felipe; Lucey, Alice J.; Oliero, Manon; Walter, Jens
Adequate dietary fiber intake from plant foods is critical for the prevention of noncommunicable chronic diseases (NCDs). However, across industrialized nations, consumption remains insufficient to meet established intake recommendations. This gap provides a strong rationale to include functional fibers into processed foods or use them as supplements, although their effectiveness in reducing NCD risk is inconclusive . In this review, we examine current nutritional strategies to optimize fiber intake, spanning whole-plant foods, processed foods made or enriched with fiber-containing ingredients, and fiber supplements. We examine the structure and physicochemical properties of the fiber types represented in these strategies and explore the mechanisms by which they influence the gut microbiome and NCD risk markers. Drawing on evidence from human intervention studies, we critically assess the strengths and limitations of each strategy to improve health outcomes and propose a framework for the effective and systematic integration of fiber into nutrition and food science.
Lactobacillus acidophilus for infant colic and microbiota modulation: a randomized clinical trial
(2026) Vaz, Sáskia Ribeiro; Tofoli, Marise Helena Cardoso; Avelino, Melissa Ameloti Gomes; Mota, João Felipe; Araujo Filho, Humberto Bezerra de; Costa, Paulo Sérgio Sucasas da
Background Infantile colic affects up to 25% of infants during the early weeks of life. Dysbiosis plays a prominent role in its pathogenesis, supporting the potential therapeutic role of probiotics. We aimed to evaluate the efficacy of Lactobacillus acidophilus NCFM versus placebo in infant colic and microbiota modulation. Methods A double-blind, placebo-controlled randomized trial was conducted with 60 infants with colic, randomly assigned to receive five drops of L. acidophilus NCFM (1 × 109 CFU) or placebo for 28 days. Data on responders (subjects with a colicky full-force crying/fussing time reduction of ≥ 50% from baseline), daily fussing and crying time, adverse effects, and maternal and child characteristics were collected. Changes in gut microbiota and fecal calprotectin were also evaluated. The study was registered at ensaiosclinicos.gov.br (RBR-5pp4nks). Results The primary endpoint (proportion of responders at Day 28) was not significantly different between groups (p = 0.240). A higher responder rate was observed in the intervention group at Day 14 in exploratory analyses (p = 0.045); however, this result was attenuated after correction for multiple comparisons. No statistical difference was observed in calprotectin concentration (p = 0.687), infant mood (p = 0.720), fussing and crying time (p = 0.524). A higher diversity was observed in the breastfed and formula-fed groups utilizing probiotics, but not in the formula-fed group receiving placebo. A high relative abundance of Akkermansia was identified in the probiotic group. Ruminococcus was identified in both groups before and after the intervention. Conclusions Intervention did not significantly improve the proportion of responders at Day 28, the primary endpoint. An apparent benefit at Day 14 emerged in secondary. The use of L. acidophilus NCFM was able to improve some aspects of infants’ intestinal microbiota. Also, there was no statistical difference in calprotectin and infant mood. The use of L. acidophilus NCFM was safe for this population.
A genotype-guided nutritional intervention to reduce cardiometabolic risk factors in young adults: Study protocol for a randomized controlled trial
(2025) Rodrigues, Karina; Mendes, Marcela Moraes; Gedda, Lana Pacheco Franco; Nascimento-Silva, Nara Rúbia Rodrigues do; Oliveira, Mariana Policena Rosa de; Silva, Flávia Custódia Ferreira; Xavier, Flávia Campos Corgosinho; Coelho, Kristy Soraya; Lajolo, Franco Maria; Aldrighi, José Mendes
Background & aims: Cardiometabolic diseases (CMD), including cardiovascular disease, obesity and diabetes, are major public health challenges influenced by lifestyle factors (e.g., diet), vitamin D status, and genetic predisposition. Single nucleotide polymorphisms (SNPs) contribute to genetic risk scores for CMD-related traits (M-GRS) and recent research suggests that genotype-based nutritional interventions have the potential to reduce these risks. This study aims to evaluate the effectiveness of genotype-guided nutritional interventions versus standard dietary recommendations in young adults. Methods: This 12-month study includes a 6-month intervention phase and a 6-month free-living phase. Data will be collected at baseline, 3, 6 and 12 months. We plan to recruit young adults (aged 23-29) previously genotyped from the Obesity, Lifestyle, and Diabetes in Brazil (BOLD) study and randomized by BMI, sex, and M-GRS based on 34 SNPs. The control group will follow a standard Brazilian diet with CMD-related recommendations and 1000 IU of vitamin D3 daily. The personalized intervention group will receive a genotype-guided dietary plan based on gene-diet interactions for SNPs in the M-GRS, along with personalized vitamin D3 supplementation (1000 or 4000 IU) based on their genetic risk for deficiency (D-GRS). Body composition, biochemical markers and metabolomics will be assessed, with the reduction in body fat percentage as the primary outcome. Discussion: This study will contribute to precision nutrition by assessing genotype-guided dietary recommendations for CMD risk management, potentially demonstrating how genetic information can optimize dietary interventions and reduce CMD burdens, improving overall health outcomes.
Curcumin supplementation improves gastrointestinal symptoms in women with severe obesity: a double-blind, randomized, placebo-controlled trial-a pilot study
(2025) Kattah, Fabiana Martins; Figueiredo, Nayra; Bezerra, Kamilla Kenned; Oliveira, Emilly Santos; Melo, Cinara Costa de; Lima, Gislene Batista; Cavalcante, Jocélia Paula Rocha; Benetti, Beatriz Bacheschi do Carmo; Lima, Glaucia Carielo; Mota, João Felipe; Xavier, Flávia Campos Corgosinho
Gastrointestinal symptoms, including reflux, bloating, dyspepsia, stomach pain, and altered bowel patterns, are commonly reported in individuals with severe obesity and may significantly impact quality of life. Background/Objectives: Curcumin, a bioactive compound found in turmeric (Curcuma longa L.), possesses anti-inflammatory and antioxidant properties and has been investigated for its potential role in gastrointestinal health. However, its effects in individuals with severe obesity remain unclear. Methods: This double-blind, placebo-controlled clinical trial aimed to evaluate the effect of curcumin supplementation on gastrointestinal symptoms in women with severe obesity. Thirty-one women with a body mass index (BMI) ≥ 40 kg/m2 undergoing bariatric surgery were randomized to receive either 1500 mg of curcumin (98.75%) or a placebo (1500 mg corn starch) daily for 13 weeks. Gastrointestinal symptoms were assessed using the Gastrointestinal Symptom Rating Scale (GSRS), and stool consistency was assessed using the Bristol Stool Scale. Anthropometric measurements were also collected. Results: Participants had an average age of 33.1 ± 8 years and a BMI of 45.6 ± 3.31 kg/m2. No differences were observed between groups at baseline. At the end of the study, the curcumin group showed a significant reduction in the GSRS's total score compared to the placebo group (p = 0.002), with improvements in eructation (p = 0.011) and constipation (p = 0.007). Additionally, the curcumin group showed reduced BMI (p = 0.019) and neck circumference (p = 0.042). Conclusions: These findings suggest that curcumin supplementation may alleviate some gastrointestinal symptoms and improve anthropometric measures in women with severe obesity, providing a potential dietary strategy.
Multidisciplinary therapy to target obesity and its complications in adult population: a narrative review
(2026) Dâmaso, Ana Raimunda; Xavier, Flávia Campos Corgosinho; Masquio, Deborah Cristina Landi; Figueiredo, Nayra; Kattah, Fabiana Martins; Cercato, Cintia; Tock, Lian; Campos, Raquel Munhoz da Silveira
Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling. When lifestyle changes are not sufficient in adults, medication prescription and bariatric surgery may be recommended. The aim of this narrative review is to summarize the underlying mechanisms and effects of multidisciplinary therapy in the control of obesity and its complications in adults. [Correction added on 21 January 2026, after first online publication: The previous sentence has been corrected in this version.] All types of clinical studies developed in an adult population were included. Different types of multidisciplinary therapy (short- and long-term) in the primary and secondary settings were identified. Multidisciplinary therapy seems to be useful in the control of adverse effects of obesity, including reductions in biomarkers of inflammation, cardiometabolic risk factors, dyslipidemia, diabetes, hypertension, metabolic syndrome, nonalcoholic fatty liver diseases, atherosclerosis, cardiovascular disease, obstructive sleep apnea, and psychosocial outcomes. These results highlight the importance of targeting obesity and its complications in a holistic approach with a multidisciplinary team acting together.
Formação e práticas educativas de professores de medicina: uma abordagem etnográfica
(2013-10) Costa, Nilce Maria Silva Campos
This issue describes the use of the ethnographic approach of the qualitative research to investigate the teaching practices of the medicine professors. In addition of methodological procedures, explains the two phases: an exploratory phase, in which it had the access to the context and the phase of. Three data collecting instruments were used which complemented each other: an questionnaire which allowed the establishment of a professional profile of professors of medicine, a semistructured interview with questions relating to the professor’s career experience and also, direct observation in the classroom with a registration of the teaching practices and a description of the teaching strategy. This research allows to ensure the reality and verifies that the dissatisfactions and the ideas of transformations presented by medicine teachers reflects the interest in a genuine transformation of the teaching that contemplate the formation of the physician in Brazilian society. Between the possibilities sight with this kind of research glimpses the professor as investigator of his own educational practice.
Formação e atuação de nutricionistas dos Núcleos de Apoio à Saúde da Família
(2015-04) Kogawa, Camilla Botêga Aguiar; Costa, Nilce Maria da Silva Campos
Objective The aim of this study was to analyze the education and work of dieticians from the Family Health Support Centers in the state of Goiás. Method This is a descriptive, exploratory, cross-sectional study with dieticians from these centers. The dieticians answered a self-administered questionnaire with open and closed questions that characterized them, their education, and their work. Research Twenty-two female dieticians from Family Health Support Centers participated in the study, representing 88.0% of the total. Of these, 59.1% had graduated less than three years ago; 13.6% specialized in family health; and only 27.3% felt capable of performing their job based on a reflection about the socioeconomic, political, and cultural reality of the territory. Regarding work, 80% had temporary job contracts, which can compromise the bond between the professionals and the population; 36.4% had been working for less than one year; 18.2% received training before they started working; and 59.1% did not feel sufficiently trained to work in the centers. Only 9.1% of the participants discussed matriciamento (support given by a multidisciplinary team to another multidisciplinary team) in the meetings and used tool-related references. Team work was considered a facilitator of their actions, and not knowing the role of Family Health Support Centers was considered a hindrance. Conclusion Dieticians from the Family Health Support Centers in the state of Goiás have little professional experience, do not feel sufficiently trained to work in family health, and have difficulties understanding the local reality, as education did not give them confidence to work in the area and they have little knowledge about the centers.
Educação nutricional para pacientes em hemodiálise: controle da hipercalemia e hiperfosfatemia
(Universidade Federal de Goiás, 2020-05-04) Silva, Ana Luiza Araujo da; Stringhini, Maria Luiza Ferreira; Freitas, Ana Tereza Vaz de Souza
Nutritional education activities in hemodialysis clinics are of utmost importance for treatment engagement and consequent im provement in the quality of life of patients with Chronic Kidney Disea se (CKD). In this way, the project presented aims to provide nutritional education in the control of hyperkalaemia and hyperphosphatemia to hemodialysis patients through educational actions, which besides optimizing the time of the hemodialysis sessions help in the adhesion of the diets. Several topics were addressed throughout the project, including potassium and phosphorus intake in the DRC, through dia logic lectures using visual illustrative resources and using food bingo with images of food sources of phosphorus or potassium. The results of the activities were positive, demonstrating interest and involve ment of the majority of the patients. It was concluded that the ex tension project contributed to the health promotion of hemodialysis patients, aided in the treatment, providing knowledge and autonomy for a better quality of life of these individuals.
Hábito alimentar de mulheres com câncer de mama após intervenção nutricional
(Universidade Federal de Goiás, 2021-04-15) Martins, Karine Anusca; Morais, Carla Cristina de; Teixeira, Natascha Damião
The objective of this was to observe the presence or not of changes in the diet of women undergoing treatment for breast cancer, after the implementation of a nutritional educational intervention program. Qualitative quantitative intervention study, institutionally based, with 12 women, diagnosed with breast cancer, between 30 and 72 years old. Six health education activities were carried out. The following were analyzed: age, education, income, marital status, nutritional status by anthropometry and feeding by the "How are you eating?" test from the Ministry of Health. For a quantitative analysis of the data using Epi-Info considering the level of p <0.05. It was noticed after educational intervention important qualitative changes in the participants' diet, such as: reduction in the consumption of red meat, sweets, fried foods and processed foods and an increase in the consumption of water, fruits and vegetables, in the fractionation of meals and the practice of physical activity, without statistical. It was concluded that the extension actions that promote the improvement of the quality of life, even if it is individual, are essential to reduce the risk of recurrences.
Beta-caroteno e câncer
(1998-12) Naves, Maria Margareth Veloso
The subject β-carotene and cancer has been studied for more than twenty years, through epidemiologic and experimental researches.Observational epidemiologic studies, both prospective and retrospective, have suggested strongly that high intake of vegetables and fruits which are sources of β-carotene is associated with reduced risk of cancer, specially of lung cancer. However, the results of intervention trials do not demonstrate a preventive potential of β-carotene. Nevertheless, in many studies in experimental animals and in cell cultures, this carotenoid had been shown to act as a potent cancer chemopreventive agent and mechanisms have been proposed to explain this protective effect on biological systems. Researchers suggest that β-carotene protects against cancer, in the amounts easily attained by the consumption of a wide variety of diets, and the chronic pharmacological supplementation is not recommended for healthy populations and for heavy smokers.
Nutrição, atividade física e obesidade em adultos: aspectos atuais e recomendações para prevenção e tratamento
(2004) Beraldo, Fernanda Carneiro; Naves, Maria Margareth Veloso; Vaz, Inaiana Marques Filizola
Obesity is a chronic nontransmissible disease, characterized by excessive body weight, whose prevalence is rising at alarming levels in developed societies as well as in developing countries. In Brazil, overweight (body mass index – BMI ≥ 25.0kg/m2) and obesity (BMI ≥ 30.0kg/m2) reached 40% of women and 27% of men in the 80’s and 90’s decades. A diet high in energy density and a sedentary lifestyle are considered the most relevant factors that could explain the increasing obesity in western societies. For obese people, it is recommended a loss between 5 and 30% of body weight (about 0.5 to 1.0kg/week), depending of the levels of obesity, by means of a decreasing of 500 to 1000kcal in daily diet. The low energy diet must be balanced in terms of macronutrients and it must contain foods low in energy density, i.e., restriction in simple carbohydrates-rich foods and alcohol and increase in consumption of foods rich in fiber, vitamins, minerals and water. Both physical activity and diet must be used to lose weight and to maintain the weight lost. Physical exercise with moderate intensity is recommended for at least 30 min/day, including routine activities. Thereby, healthy food habits and active lifestyle must be essential goals in the prevention and treatment programs of obesity.
Fortificação de alimentos com o pó da casca de ovo como fonte de cálcio
(2007-03) Naves, Maria Margareth Veloso; Fernandes, Daniela Canuto; Prado, Carla Marques Maia do; Teixeira, Luiz Savio Medeiros
Egg shell powder is used as a calcium source in a nutritional supplement known as “multimistura” that has been distributed in Brazil by non-governmental organizations. The objectives of this research were to fortify traditional, low cost and easy to prepare dishes with egg shell powder and to estimate the nutritional contribution of each portion to the calcium daily intake. Ten common dishes were prepared and fortified with egg shell powder (with 37.4% of calcium) at the rate of 1g to 100 g of cereal or flour used in the processing foods. The fortified foods showed a range of calcium concentrations between 111.5 mg and 506.4 mg.100 g -1, which were significantly higher than the contents of the original formulations without fortification. Mean portions of fortified dishes provide about 14 to 32% of the nutritional calcium references for adults. It was concluded that traditional dishes fortified with egg shell powder could contribute significantly to the adequate calcium intake and to prevent calcium deficiency, mainly osteoporosis, in individuals of different age groups and social levels.
Percepção dos coordenadores de curso de Nutrição sobre o Exame Nacional de Desempenho dos Estudantes (Enade/2004)
(2009-04) Domene, Semíramis Martins Álvares; Loureiro, Helena Maria Simonard; Pedrosa, Lucia de Fatima Campos; Naves, Maria Margareth Veloso; Diez Garcia, Rosa Wanda; Tuma, Rahilda Conceição Ferreira Brito; Herrmann, Stela Maris
Analyze the perception of the coordinators of Nutrition Graduation Courses about the Brazilian National Examination of Student Performance (Enade/2004) by using a questionnaire which contained eleven questions, being ten objective and one subjective, enclosing the diverse contexts of the exam. The Enade had positive evaluation for the purpose of the social and economic questionnaire; questions selection, quality and comprehensiveness of the questions of general and specific components. According to the coordinators perceptions, the negative aspect of the exam was the probably manner of inducing to a hierarchic classification of the courses, instead of evaluating the student’s performance. These analyses could be proposals for the next examinations, as well as contributions for the improvement of the pedagogic projects of Nutrition Courses and to approaching the superior education in this area.
Qualidade microbiológica, aceitabilidade e valor nutricional de barras de cereais formuladas com polpa e amêndoa de baru
(2010-12) Lima, Jean Carlos Rodrigues; Freitas, Jullyana Borges de; Fonseca, Ludmila de Paula Czeder; Fernandes, Daniela Canuto; Naves, Maria Margareth Veloso
The aim of this study was to evaluate the microbiological quality, the acceptability and the nutritional characteristics of cereal bars made with pulp and almond of the baru (native fruit from Brazilian Savanna). The fruits were collected in the East and South East Regions from Goiás state, in August 2008. The formulations of cereal bars were prepared with fixed proportion of almond in replacement to the nuts and dried fruits, and increasing proportions of baru pulp (0%, 5% and 10%) in replacement to the oat bran. The cereal bars were evaluate for microbiological quality through counts of coliforms, Bacillus cereus, positive Staphylococci coagulase and Salmonella, and for the overall acceptance, appearance and purchase intent. The accepted bars were submitted to the analysis of centesimal composition, including total dietary fiber and its fractions (soluble and insoluble). All the samples were in accordance with the microbiological standard for food. The cereal bars had good overall acceptance and good levels of purchase intent, and showed levels of carbohydrates and lipids similar to the commercial cereal bars and high protein content (10.64 g/100 g), due to the addition of baru almond, a source of protein and lipids of good nutritional quality. Cereal bars made with the pulp and almond of the baru are source of energy, proteins and carbohydrates and present a high level of dietary fiber (15.72 g/100 g). The full utilization of baru in processed foods adds value to the fruit and nutritional quality to the product, contributing to the sustainable use of this native fruit.
Composição química de nozes e sementes comestíveis e sua relação com a nutrição e saúde
(2010-04) Freitas, Jullyana Borges; Naves, Maria Margareth Veloso
This systematic review compares the chemical composition among different types of nuts and edible seeds with regard to nutrients and other bioactive compounds and relates this composition to nutrition and health. This literature review was based on Biological Abstracts, CAB Abstracts, Food Science and Technology Abstracts, Medline and Lilacs, in accordance with the following selection criteria: original research articles published in the last five years in Brazilian or international journals in the fields of Food Science, Medicine I and Medicine II, indexed in the Institute for Scientific Information. The articles were analyzed according to pre-established quality criteria. True nuts (almonds, hazelnuts, chestnuts, cashew nuts, Brazil nuts, macadamia nuts, walnuts and pistachios) and edible seeds (peanuts and baru almonds) are good sources of lipids and proteins. The lipid fractions are composed especially of oleic (C18:1) and linoleic (C18:2) fatty acids, with emphasis on the ω-6 to ω-3 relation in macadamia, walnut, chestnut and baru almond, whose profiles favor the reduction of cardiovascular disease risk. Their proteins present an amino acid profile that meets the requirements of school children and contain more sulfur-containing amino acids than legumes such as beans. These nuts and edible seeds are also good sources of phytoesterols, mainly.β-sitosterol; minerals, particularly calcium, iron, zinc, selenium and potassium; tocopherols, especiallyα-tocopherol; and insoluble fiber. These nutrient-dense foods contain bioactive substances that maximize their beneficial health effects and, for this reason, their study and consumption should be encouraged.

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