FF - Faculdade de Farmácia
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A FF - Faculdade de Farmácia, da Universidade Federal de Goiás, oferece curso de Graduação em: Farmácia. Além de Especialização em: Fitoterapia; e, Citologia Clínica.
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Item Determinação da atividade antibacteriana e toxicidade do ácido acético e vinagres branco e tinto(Marize Campos Valadares, 2007-12) Utyama, Iwa Keiko Aida; Andrade, Denise de; Watanabe, Evandro; Pimenta, Fabiana Cristina; Ito, Izabel YokoAcetic acid and vinegar have a long history and human applicability, including the clinical treatment of wounds. The aim of this study was to evaluate in vitro antibacterial activity and toxicity of acetic acid and white and red vinegars. The antibacterial activity was evaluated by Maximum Inhibitory Dilution (MID) of acetic acid and vinegars against hospital bacteria: Pseudomonas aeruginosa (20), Escherichia coli (20), Staphylococcus aureus (20), and the toxicity based on the mortality percentage of Artemia salina Leach. The MIDs of acetic acid against P.aeruginosa, E.coli and S.aureus were at 1:400. Moreover, the white and red vinegars inhibited all E. coli and S. aureus at 1:50 and 1:33, respectively. However, the red and white vinegars showed MIDs against P. aeruginosa at 1:67 and 1:50, respectively. The acetic acid in natura, 1:50, 1:100, 1:200, 1:400 e 1:800 demonstrated toxicity against A. salina Leach. Both white and red vinegars did not show toxicity at 1:400 and 1:800. In conclusion, it is possible to consider that there is an inverted proportional relation of the acetic acid and vinegars dilutions, with the antibacterial activity and the toxicity. Besides, this study provides some relevant technical information that can elucidate about risks of inadequate use (dilution/concentration) these products in vivo, specially, on wounds.