FF - Faculdade de Farmácia
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A FF - Faculdade de Farmácia, da Universidade Federal de Goiás, oferece curso de Graduação em: Farmácia. Além de Especialização em: Fitoterapia; e, Citologia Clínica.
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Item Uma abordagem sobre métodos analíticos para determinação da atividade antioxidante em produtos naturais(2011) Borges, Leonardo Luiz; Lúcio, Tathiana Carvalho; Gil, Eric de Souza; Barbosa, Eduardo FernandesAntioxidants have been placing a highlighted position in the pharmaceutical industry, becoming the systematic research of these compounds important, for their ability to neutralize harmful agents in biological systems such as free radicals. In this work were evaluated some methodologies to determine the antioxidant capacity of some complex systems, as plant extracts, food, wine, among others. The detection of antioxidants was based on three categories of methods: electrochemical, colorimetric (DPPH e ABTS), and biological. Besides these, other instrumental techniques were pointed out, showing the versatility of the mechanisms that can be use to unveil the concentration of these substances. The HPLC (High Performance Liquid Chromatography) is a very useful tool in the identification and quantification of these compounds and can be coupled to the DPPH method. Each analytical method cited here has advantages and limitations, and the approach presented in this work ranges within these two parameters.Item Avaliação da capacidade antioxidante em amostras comerciais de canela por métodos voltamétricos e espectrofotométricos(Universidade Federal de Goiás, 2022-08-16) Vasconcelos, Igor André Alves; Gil, Eric de Souza; Moreno, Emily Kussmaul Gonçalves; Moreno, Emily Kussmaul Gonçalves; Silva, Giovanna Nascimento de Mello e; Machado, Fábio BahlsThis study aimed to analyze the antioxidant capacity in commercial cinnamon (Cinnamomum sp.), given the growing concern about cellular damage from reactive oxygen species, as well as the desire for healthy and natural food, aiming to compare traditional and innovative methods for the determination of antioxidant capacity. The traditional methods performed were the scavenging of the free radical DPPH (1,1-diphenyl-2-picrylhydrazyl) and the capture of the cation of the radical ABTS (2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate), measured by the spectrophotometry technique. For electrochemical studies, voltammetric techniques such as CV, DPV and SWV were performed and the Electrochemical Index (IE) was calculated. The results of ABTS, DPPH and IE indicated significant differences between the 17 samples. A matrix was calculated, comparing the methods, where it was possible to observe a high statistical correlation (c.a 0.6) between them. It was concluded that the cinnamon samples have high antioxidant capacity and the methodologies used are equivalent.