Cerumenogram: a new frontier in cancer diagnosis in humans

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dc.creatorBarbosa, João Marcos Gonçalves
dc.creatorPereira, Naiara Zedes
dc.creatorDavid, Lurian Caetano
dc.creatorOliveira, Camilla Gabriela de
dc.creatorSoares, Marina Ferraz Gontijo
dc.creatorAvelino, Melissa Ameloti Gomes
dc.creatorOliveira, Anselmo Elcana de
dc.creatorShokry, Engy
dc.creatorAntoniosi Filho, Nelson Roberto
dc.date.accessioned2023-06-16T11:07:27Z
dc.date.available2023-06-16T11:07:27Z
dc.date.issued2019-08
dc.description.abstractCancer is the deadliest human disease and the development of new diagnosis methods is important to increase the chances of a cure. In this work it was developed a new method, named here for the frst time as cerumenogram, using cerumen (earwax) as a new biomatrix for diagnosis. Earwax samples collected from cancer patients (cancer group) and cancer-free patients (control group) were analyzed by Headspace/Gas Chromatography-Mass Spectrometry (HS/GC-MS), following with multivariate analysis steps to process the raw data generated. In total, 158 volatile organic metabolites (VOMs) were identifed in the cerumen samples. The 27 selected as potential VOMs biomarkers for cancer provided 100% discrimination between the cancer and control groups. This new test can thus be routinely employed for cancer diagnoses that is non-invasive, fast, cheap, and highly accurate.pt_BR
dc.identifier.citationBARBOSA, João Marcos Gonçalves Barbosa et al. Cerumenogram: a new frontier in cancer diagnosis in humans. Scientific Reports, London, v. 9, n. 1, e11722, 2019. DOI: 10.1038/s41598-019-48121-4. Disponível em: https://www.nature.com/articles/s41598-019-48121-4. Acesso em: 14 jun. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1038/s41598-019-48121-4
dc.identifier.issne- 2045-2322
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/22741
dc.language.isoengpt_BR
dc.publisher.countryGra-bretanhapt_BR
dc.publisher.departmentInstituto de Química - IQ (RMG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleCerumenogram: a new frontier in cancer diagnosis in humanspt_BR
dc.typeArtigopt_BR

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