Nutritional and metabolic risk factors for insulin resistance in adults

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dc.creatorMota, João Felipe
dc.creatorMoreto, Fernando
dc.creatorMedina, Wilson Luvizoto
dc.creatorPereira, Elaine Cristina Leite
dc.creatorBurini, Roberto Carlos
dc.date.accessioned2019-02-12T11:10:56Z
dc.date.available2019-02-12T11:10:56Z
dc.date.issued2011-08
dc.description.abstractThe purpose of this study is to investigate the association of insulin resistance (IR) with dietary, fitness, anthropometric and other components of Metabolic Syndrome (MS) in adult participants. Cross- sectional study of 80 adult participants (58±8 years old) were clinically and ethically selected. They were all assessed for anthropometry, dietary habits, plasma biochemistry and indirect measurement of maximal oxygen uptake (VO 2 max). Participants were diagnosed for MS by IDF criterion and placed in 3 different groups using tertiles of HOMA-IR. Values were statistically correlated with the remaining variables. Predictors of IR were determined by multivariate regression analysis. HOMA-IR was significant (p<0.001) and positively associated with MS prevalence (r=0.67), C-reactive protein (r=0.58), waist circumference (WC) (r=0.55), servings of fat consumption (r=0.52), body weight (r=0.43), body mass index (r=0.40), uric acid (r=0.40), inversely correlated associated with HDL-c (r=-0.56), VO 2 max (r=- 0.28), ingested fibers (r=-0.47) and fruits (r=-0.39). The fiber intake discriminated tertiles of HOMA-IR (G1<G2<G3). The variables considered independent predictors of HOMA-IR were WC, fat intake, MS, low fiber intake, low muscle mass and high plasmatic concentrations of uric acid. The highest values of HOMA-IR (P75) were positively associated with consumption of refined grains, uric acid, triglycerides, low consumption of fruit and low HDL-c. Main determinants of IR are preventable factors.pt_BR
dc.identifier.citationMOTA, João Felipe et al. Nutritional and metabolic risk factors for insulin resistance in adults. International Journal of Nutrition and Metabolism, Gillingham, v. 3, n. 7, p. 90-96, Aug. 2011.pt_BR
dc.identifier.issne- 2141-2332
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/17047
dc.language.isoengpt_BR
dc.publisher.countryGra-bretanhapt_BR
dc.publisher.departmentFaculdade de Nutrição - FANUT (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectInsulin resistancept_BR
dc.subjectPhysical fitnesspt_BR
dc.subjectOxidative stresspt_BR
dc.subjectEating habitspt_BR
dc.subjectInflammationpt_BR
dc.subjectLipoproteinspt_BR
dc.titleNutritional and metabolic risk factors for insulin resistance in adultspt_BR
dc.typeArtigopt_BR

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