Isolation and structural characterization of two new furanoditerpenes from Pterodon emarginatus (Fabaceae)

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dc.creatorOliveira, Leandra de Almeida Ribeiro
dc.creatorOliveira, Gerlon de Almeida Ribeiro
dc.creatorLemes, Geralda de Fátima
dc.creatorRomão, Wanderson
dc.creatorVaz, Boniek Gontijo
dc.creatorAlbuquerque, Sérgio de
dc.creatorRotta, Cristiana Gonçalez
dc.creatorLiao, Luciano Morais
dc.creatorBara, Maria Teresa Freitas
dc.date.accessioned2023-06-29T12:03:13Z
dc.date.available2023-06-29T12:03:13Z
dc.date.issued2017
dc.description.abstractA furanoditerpene-enriched fraction was obtained from the fruits of Pterodon emarginatus and submitted to semipreparative high performance liquid chromatography (HPLC). Two new furanoditerpenes, 6α,19β-diacetoxy-7β,14β-dihydroxyvouacapan and 6α-acetoxy7β,14β-dihydroxyvouacapan, in addition to the known compound methyl 6α-acetoxy7β-hydroxyvouacapan-17β-oate were obtained. Compound structures were determined by 1D and 2D nuclear magnetic resonance (NMR) experiments and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS). The major compound methyl 6α-acetoxy-7β-hydroxyvouacapan-17β-oate was evaluated against promastigote forms of Leishmania amazonensis and L. braziliensis, presenting the concentration which causes lysis on 50% of parasites IC50 < 30 µg mL-1.pt_BR
dc.identifier.citationOLIVEIRA, Leandra A. R. et al. Isolation and structural characterization of two new furanoditerpenes from Pterodon emarginatus (Fabaceae). Journal of the Brazilian Chemical Society, Campinas, v. 28, n. 10, p. 1911-1917, 2017. DOI: 10.21577/0103-5053.20170029. Disponível em: https://s3.sa-east-1.amazonaws.com/static.sites.sbq.org.br/jbcs.sbq.org.br/pdf/2016-0749AR.pdf. Acesso em: 21 jun. 2023.pt_BR
dc.identifier.doi10.21577/0103-5053.20170029
dc.identifier.issne- 1678-4790
dc.identifier.issn0103-5053
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/22820
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Química - IQ (RMG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPterodonpt_BR
dc.subjectFuranoditerpenespt_BR
dc.subjectVouacapanpt_BR
dc.subjectLeishmaniapt_BR
dc.titleIsolation and structural characterization of two new furanoditerpenes from Pterodon emarginatus (Fabaceae)pt_BR
dc.typeArtigopt_BR

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