Bioactivity of crude ethanol extract and fractions of Eugenia uniflora (Myrtaceae) in the hepatopancreas of Oreochromis niloticus L.

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dc.creatorFiuza, Tatiana de Sousa
dc.creatorSilva, Paulo César
dc.creatorPaula, José Realino de
dc.creatorTresvenzol, Leonice Manrique Faustino
dc.creatorSaboia-Morais, Simone Maria Teixeira de
dc.date.accessioned2018-09-27T11:30:11Z
dc.date.available2018-09-27T11:30:11Z
dc.date.issued2009
dc.description.abstractThis study evaluates the bioactivity of the crude ethanol extract and ethyl acetate, hexane and chloroform fractions obtained from Eugenia uniflora leaves using the hepatopancreas of Oreochromis niloticus L. as an experimental model. The ethanol extract and fractions were administered to the fish orally with their feed. Twenty-four hours later, the fish were sacrificed and their livers dissected, fixed in neutral formalin, embedded in paraffin and sectioned. Histological analyses were performed using Masson’s trichrome and Haematoxylin-Eosin. Histochemical studies were performed using Feulgen, PAS (Periodic Acid Schiff) and PAS + salivary amylase and Sudan IV stain. The qualitative analysis of the material showed that the crude extract and the ethyl, chloroform and hexane fractions induced vasodilation, vascular congestion and toxicity due to the presence of eosinophilic granular cells, rodlet cells, some leukocytic infiltrate and rare focal necroses. The Nile tilapia proved to be a satisfactory model for screening plant products.pt_BR
dc.identifier.citationFIUZA, Tatiana S. et al. Bioactivity of crude ethanol extract and fractions of Eugenia uniflora (Myrtaceae) in the hepatopancreas of Oreochromis niloticus L. Biological Research, Santiago, v. 42, n. 4, p. 401-414, 2009.pt_BR
dc.identifier.doi10.4067/S0716-97602009000400002
dc.identifier.issn0716-9760
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/16072
dc.language.isoengpt_BR
dc.publisher.countryChilept_BR
dc.publisher.departmentFaculdade de Farmácia - FF (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectFishpt_BR
dc.subjectVasodilationpt_BR
dc.subjectMedicinal plantspt_BR
dc.titleBioactivity of crude ethanol extract and fractions of Eugenia uniflora (Myrtaceae) in the hepatopancreas of Oreochromis niloticus L.pt_BR
dc.typeArtigopt_BR

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