Alternativas ao Carbopol 940 na fabricação de álcool em gel
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Data
2021-01-15
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Universidade Federal de Goiás
Resumo
At the end of 2019, a new epidemic of global proportions, motivated by a virus called SARS-CoV-2, (COVID-19), originating in China, forced countless countries to mo-bilize to face the health implications of the infection and in the economy. Hygiene through constant hand washing in an appropriate manner, using water and soap and in the absence of alcohol-based disinfectants, was the main recommendation of the World Health Organization. In view of the great demand for such disinfectants based on of al-cohol, there was a shortage of assets used to produce it worldwide, so this study aimed to develop alcohol gel formulations with different thickener alternatives in order to meet the high demand for this product. The methodology used was the development of 12 al-ternative formulations, where the compatibility between the different gelling agents with the reference thickener was verified. Organoleptic tests (appearance, color and odor), physical-chemical tests (pH, viscosity and alcohol content) and sensory analysis of sti-ckiness were performed after subjecting the samples to extreme temperature conditions and centrifugation tests, aiming at predicting possible instabilities. It was concluded that the best alternative to replace Carbopol, a polymer known commercially and most used to manufacture alcohol in gel, was Luviset 360, a thickener created by Badische Anilin & Soda Fabrik-BASF
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Álcool gel, Antissépticos, Carbopol, Alcohol gel, Antiseptics, Carbopol
Citação
CRUZ, Camila Vieira Milo Bela. Alternativas aos carbômeros para fabricação de álcool em gel. 2021. 47 f. Trabalho de Conclusão de Curso (Graduação) - Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, 2021.