Antimicrobial activity of the crude ethanol extract from Pimenta pseudocaryophyllus

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dc.creatorPaula, Joelma Abadia Marciano de
dc.creatorPaula, José Realino de
dc.creatorPimenta, Fabiana Cristina
dc.creatorRezende, Maria Helena
dc.creatorBara, Maria Teresa Freitas
dc.date.accessioned2020-02-05T11:15:05Z
dc.date.available2020-02-05T11:15:05Z
dc.date.issued2009
dc.description.abstractThe antimicrobial activity of the crude ethanol extract from Pimenta pseudocaryophyllus (Gomes) L. R. Landrum (Myrtaceae), collected at two locations in Brazil, was investigated. Leaf samples were collected in April 2005 and in September 2005, both in Brasília, DF, Brazil, and in July 2000 in São Gonçalo do Abaeté, MG, Brazil. They were dried, crushed and used to obtain three crude ethanol extracts. The agar diffusion test was used for antimicrobial activity screening and the agar dilution method for determining the minimal inhibitory concentration (MIC). In assay conditions, extracts I, II and III demonstrated antimicrobial activity against Gram-positive Staphylococcus aureus, Micrococcus luteus, M. roseus, Bacillus cereus, B. atrophaeus, and B. stearothermophilus (MIC 0.39062 to 12.5 mg/mL, MIC 0.78125 to 1.5625 mg/mL and MIC 0.39062 to 1.5625 mg/mL, respectively), against Gram-negative Pseudomonas aeruginosa (MIC 0.39062 to 3.125 mg/mL, MIC 1.5625 mg/mL and MIC 0.78125 to 1.5625 mg/mL, respectively), against clinical isolates of Pseudomonas stutzeri (MIC 0.39062 to 0.78125 mg/mL, MIC 0.78125 to 1.5625 mg/mL, MIC 0.78125 to 1.5625 mg/mL, respectively) and also against Candida albicans fungi (MIC 0.19531 mg/mL for the extracts I, II and III). This study showed that the antimicrobial activity of P. pseudocaryophyllus might be considered sufficient to encourage further studies to isolate and identify its active principles. Pharmacological and toxicological studies are also necessary, followed by studies regarding the culturing and managing processes of this vegetable.pt_BR
dc.identifier.citationPAULA, Joelma Abadia Marciano de; PAULA, José Realino de; PIMENTA, Fabiana Cristina; REZENDE, Maria Helena; BARA, Maria Teresa Freitas. Antimicrobial activity of the crude ethanol extract from Pimenta pseudocaryophyllus. Pharmaceutical Biology, New York, v. 47, n. 10, p. 987-993, 2009.pt_BR
dc.identifier.doi10.1080/13880200902969462
dc.identifier.issn1388-0209
dc.identifier.issne- 1744-5116
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/18607
dc.language.isoengpt_BR
dc.publisher.countryEstados unidospt_BR
dc.publisher.departmentFaculdade de Farmácia - FF (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAgar diffusion testpt_BR
dc.subjectFungipt_BR
dc.subjectAgar dilution methodpt_BR
dc.subjectMinimal inhibitory concentrationpt_BR
dc.subjectBacteriapt_BR
dc.titleAntimicrobial activity of the crude ethanol extract from Pimenta pseudocaryophylluspt_BR
dc.typeArtigopt_BR

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