Anti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae)

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dc.creatorMedina, Rebeca Previate
dc.creatorMoura, Vagner Marques de
dc.creatorSilva, Cleuza Conceição da
dc.creatorOliveira, Cecilia Maria Alves de
dc.creatorKato, Lucilia
dc.creatorPomini, Armando Mateus
dc.creatorCarvalho, João Ernesto de
dc.creatorGois Ruiz, Ana Lúcia Tasca
dc.creatorAmado, Ciomar Aparecida Bersani
dc.creatorOliveira, Silvana Maria de
dc.date.accessioned2023-09-05T10:37:14Z
dc.date.available2023-09-05T10:37:14Z
dc.date.issued2018
dc.description.abstractThe crude extract and fractions from the branches of Ixora brevifolia, a tree found in the Brazilian Cerrado, were tested for anti-inflammatory and in vitro antiproliferative effects. The crude extract and n-hexane fraction exhibited significant inhibition of ear oedema in mice, while n-hexane-precipitated and chloroform fractions strongly inhibited the myeloperoxidase activity in ear tissue. The n-hexane and n-hexane-precipitated fractions showed strong growth inhibition for glioma cell line and the hydromethanolic fraction inhibited the growth of leukaemia cell line.pt_BR
dc.identifier.citationMEDINA, Rebeca P. et al. Anti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae). Natural Product Research, Abingdon, v. 32, n. 11, p. 1357-1360, 2018. DOI: 10.1080/14786419.2017.1344654. Disponível em: https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1344654. Acesso em: 28 ago. 2023.pt_BR
dc.identifier.doi10.1080/14786419.2017
dc.identifier.issn1478-6419
dc.identifier.issne- 1478-6427
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/14786419.2017.1344654
dc.language.isoengpt_BR
dc.publisher.countryGra-bretanhapt_BR
dc.publisher.departmentInstituto de Química - IQ (RMG)pt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectIxora brevifoliapt_BR
dc.subjectRubiaceaept_BR
dc.subjectAntiproliferative activitypt_BR
dc.subjectAnti-inflammatory activitypt_BR
dc.titleAnti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae)pt_BR
dc.typeArtigopt_BR

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