Treament and prevention of anemia with ferrous sulfate plus folic acid in children attending daycare centers in Goiânia, Goiás State, Brazil: a randomized controlled trial

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dc.creatorHadler, Maria Claret Costa Monteiro
dc.creatorSigulem, Dirce Maria
dc.creatorAlves, Maria de Fátima Costa
dc.creatorTorres, Vinicius Montenegro
dc.date.accessioned2022-01-20T12:03:57Z
dc.date.available2022-01-20T12:03:57Z
dc.date.issued2008
dc.description.abstractThe objective of this study was to assess the prevalence of anemia and the therapeutic and prophylactic response to ferrous sulfate and fo lic acid. A double-blind, randomized, controlled clinical trial was conducted with 196 children 6 to 24 months of age enrolled in municipal day care centers in Goiânia, Goiás State, Brazil. The children were assigned to two treatment groups that received a daily dose (5 times a week) of ei ther 4.2mg/kg/day of ferrous sulfate + folic acid (50µg) or 4.2mg/kg/day of ferrous sulfate + fo lic acid placebo. One of the prevention groups received 1.4mg/kg/day of ferrous sulfate + folic acid (50µg/day) and the other 1.4mg/kg/day of ferrous sulfate + folic acid placebo. Supplemen tation lasted approximately three months. Base line anemia prevalence was 56.1% (95%CI: 48.9- 63.1). After treatment, anemia prevalence in the folic acid group (14%) was lower than in the placebo group (34.9%) (p = 0.02). After prophy laxis in the non-anemic children, the incidence of anemia did not differ between the groups, but there was an increase in hemoglobin level in the folic acid group (p = 0.003). Iron plus folic acid was effective for the treatment of anemia and improvement of hemoglobin level in non-ane mic children.pt_BR
dc.identifier.citationHADLER, Maria Claret Costa Monteiro et al. Treament and prevention of anemia with ferrous sulfate plus folic acid in children attending daycare centers in Goiânia, Goiás State, Brazil: a randomized controlled trial. Cadernos de Saúde Pública, Rio de Janeiro, v. 24, supl. 2, p. S259-S271, 2008.pt_BR
dc.identifier.doi10.1590/S0102-311X2008001400011  
dc.identifier.issne- 1678-4464
dc.identifier.issn0102-311X
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/20197
dc.language.isoporpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFaculdade de Nutrição - FANUT (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectNutritional epidemiologypt_BR
dc.subjectChild day care centerspt_BR
dc.subjectAnemiapt_BR
dc.subjectFerrous sulfatept_BR
dc.subjectFolic acidpt_BR
dc.titleTreament and prevention of anemia with ferrous sulfate plus folic acid in children attending daycare centers in Goiânia, Goiás State, Brazil: a randomized controlled trialpt_BR
dc.title.alternativeResposta terapêutica e profilática com ferro e ácido fólico na anemia em crianças de creches públicas em Goiânia, Goiás, Brasil: ensaio clínico randomizadopt_BR
dc.typeArtigopt_BR

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