Brazilian hepatitis B vaccine: a six-year follow-up in adolescents
dc.creator | Alexandre, Kamilla Vêncio Frauzino | |
dc.creator | Martins, Regina Maria Bringel | |
dc.creator | Souza, Márcia Maria de | |
dc.creator | Rodrigues, Isolina Maria Xavier | |
dc.creator | Teles, Sheila Araujo | |
dc.date.accessioned | 2019-07-09T15:07:58Z | |
dc.date.available | 2019-07-09T15:07:58Z | |
dc.date.issued | 2012-12 | |
dc.description.abstract | The protective anti-HBs titres were examined six-year post-immunisation with the Brazilian recombinant hepatitis B vaccine. After the primary vaccination, all adolescents (n = 89) responded with protective anti-HBs titres and had a geometric mean titre (GMT) of 4031.8 mIU/mL. In 2010, 94.5% maintained protective anti-HBs (> 10 mIU/mL) antibodies, with a GMT of 236.0 mIU/mL. A positive correlation was observed between the anti-HBs titres after the primary vaccination and the titres at the six-year follow-up (p < 0.01). Eleven subjects showed anti-HBs titres suggestive of a natural booster. Prostitution and tattoos/piercings were marginally associated with natural boosters in the multivariate analysis. This study showed the first data on anti-HBs persistence following the Brazilian hepatitis B vaccine in sexually active individuals and highlights its effectiveness in the medium term. | pt_BR |
dc.identifier.citation | ALEXANDRE, Kamilla Vêncio Frauzino; MARTINS, Regina Maria Bringel; SOUZA, Márcia Maria de; RODRIGUES, Isolina Maria Xavier; TELES, Sheila Araújo. Brazilian hepatitis B vaccine: a six-year follow-up in adolescents. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 107, n. 8, p. 1060-1063, Dec. 2012. | pt_BR |
dc.identifier.doi | 10.1590/S0074-02762012000800016 | |
dc.identifier.issn | e- 1678-8060 | |
dc.identifier.uri | http://repositorio.bc.ufg.br/handle/ri/17757 | |
dc.language.iso | eng | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | Faculdade de Enfermagem - FEN (RG) | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.subject | Hepatitis B vaccine | pt_BR |
dc.subject | Adolescents | pt_BR |
dc.subject | Follow-up | pt_BR |
dc.title | Brazilian hepatitis B vaccine: a six-year follow-up in adolescents | pt_BR |
dc.type | Artigo | pt_BR |
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