Phytochemistry and antimicrobial activity of Campomanesia adamantium
Nenhuma Miniatura disponível
Data
2018-04-22
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
Campomanesia adamantium (Cambess.) O. Berg., Myrtaceae, is a plant popularly used for its antiinflammatory, anti-diarrhoeal and urinary antiseptic activities. The aims of this study were to obtain
the crude ethanolic extract and the hexane, dichloromethane, ethyl acetate, aqueous and concentrated
aqueous tannin fractions from C. adamantium leaves, perform biomonitored fractionation to isolate and
identify chemical compounds, study the chemical composition of the volatile oils of the leaves and
flowers and test the antimicrobial activity of the ethanolic extract, fractions, isolated substances and
volatile oils. Phytochemical screening and chromatographic and spectrometric techniques were used.
Volatile oils were isolated by hydrodistillation in a Clevenger apparatus and analyzed by gas chromatography/mass spectrometry. The antimicrobial activity was tested by a broth microdilution test. The
component stictane-3,22-diol was isolated and identified from the hexane fraction, while valoneic and
gallic acid were isolated and identified from the concentrated aqueous tannin fraction. The major constituents of the volatile oils of the leaves were verbenene (13.91%), -funebrene (12.05%) and limonene
(10.32%), while those of the volatile oils of the flowers were sabinene (20.45%), limonene (19.33%), -
thujene (8.86%) and methyl salicylate (8.66%). Antibacterial activity was verified for the hexane fraction,
while antifungal activity was observed for the aqueous fraction and concentrated aqueous tannin fraction
and for vanoleic acid. These results may justify the popular use of C. adamantium.
Descrição
Palavras-chave
Valoneic acid, Stictane-3,22-diol, Gallic acid, Phytochemical study, Broth microdilution, Cerrado
Citação
SÁ, Stone et al. Phytochemistry and antimicrobial activity of Campomanesia adamantium. Revista Brasileira de Farmacognosia, João Pessoa, v. 28, n. 3, p. 303-311, 2018. DOI: 10.1016/j.bjp.2018.02.008. Disponível em: https://www.sciencedirect.com/science/article/pii/S0102695X17305859?via%3Dihub. Acesso em: 21 jun. 2023.