Phytochemistry and antimicrobial activity of Campomanesia adamantium

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dc.creatorSá, Stone de
dc.creatorChaul, Luiza Toubas
dc.creatorFiuza, Tatiana de Sousa
dc.creatorTresvenzol, Leonice Manrique Faustino
dc.creatorVaz, Boniek Gontijo
dc.creatorFerri, Pedro Henrique
dc.creatorBorges, Leonardo Luiz
dc.creatorPaula, José Realino de
dc.date.accessioned2023-07-04T15:14:13Z
dc.date.available2023-07-04T15:14:13Z
dc.date.issued2018-04-22
dc.description.abstractCampomanesia adamantium (Cambess.) O. Berg., Myrtaceae, is a plant popularly used for its antiinflammatory, anti-diarrhoeal and urinary antiseptic activities. The aims of this study were to obtain the crude ethanolic extract and the hexane, dichloromethane, ethyl acetate, aqueous and concentrated aqueous tannin fractions from C. adamantium leaves, perform biomonitored fractionation to isolate and identify chemical compounds, study the chemical composition of the volatile oils of the leaves and flowers and test the antimicrobial activity of the ethanolic extract, fractions, isolated substances and volatile oils. Phytochemical screening and chromatographic and spectrometric techniques were used. Volatile oils were isolated by hydrodistillation in a Clevenger apparatus and analyzed by gas chromatography/mass spectrometry. The antimicrobial activity was tested by a broth microdilution test. The component stictane-3,22-diol was isolated and identified from the hexane fraction, while valoneic and gallic acid were isolated and identified from the concentrated aqueous tannin fraction. The major constituents of the volatile oils of the leaves were verbenene (13.91%), -funebrene (12.05%) and limonene (10.32%), while those of the volatile oils of the flowers were sabinene (20.45%), limonene (19.33%), - thujene (8.86%) and methyl salicylate (8.66%). Antibacterial activity was verified for the hexane fraction, while antifungal activity was observed for the aqueous fraction and concentrated aqueous tannin fraction and for vanoleic acid. These results may justify the popular use of C. adamantium.pt_BR
dc.identifier.citationSÁ, Stone et al. Phytochemistry and antimicrobial activity of Campomanesia adamantium. Revista Brasileira de Farmacognosia, João Pessoa, v. 28, n. 3, p. 303-311, 2018. DOI: 10.1016/j.bjp.2018.02.008. Disponível em: https://www.sciencedirect.com/science/article/pii/S0102695X17305859?via%3Dihub. Acesso em: 21 jun. 2023.pt_BR
dc.identifier.doi10.1016/j.bjp.2018.02.008
dc.identifier.issne- 0102-695X
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/22926
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Química - IQ (RMG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectValoneic acidpt_BR
dc.subjectStictane-3,22-diolpt_BR
dc.subjectGallic acidpt_BR
dc.subjectPhytochemical studypt_BR
dc.subjectBroth microdilutionpt_BR
dc.subjectCerradopt_BR
dc.titlePhytochemistry and antimicrobial activity of Campomanesia adamantiumpt_BR
dc.typeArtigopt_BR

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