Região Metropolitana de Goiânia (RMG)
URI Permanente desta comunidade
Navegar
Navegando Região Metropolitana de Goiânia (RMG) por Por Unidade Acadêmica "Ciencias da Saude"
Agora exibindo 1 - 20 de 83
Resultados por página
Opções de Ordenação
Item Contagem de carboidratos e perfil metabólico de adolescentes com diabetes melito tipo 1 atendidos no Hospital das Clínicas/UFG, Goiânia(Universidade Federal de Goiás, 2012-05-10) ALBUQUERQUE, Izabela Zibetti de; STRINGHINI, Maria Luiza Ferreira; http://lattes.cnpq.br/3705544548242014; CAMPOS, Maria Raquel Hidalgo; http://lattes.cnpq.br/9910969694141110Objective: The aim of the study was evaluated the effect of carbohydrate counting, for four months, on anthropometric parameters, body composition, biochemical and food intake in adolescents with type 1 diabetes mellitus. Methods: Clinical trial, controlled and randomized study at the Clinic of Endocrinology, Hospital das Clinicas, Federal University of Goiás, with 28 patients divided into intervention group (IG - carbohydrate counting) and control (CG - no counting carbs) and monitored fortnightly. At the beginning and end of the study data were collected on: anthropometric (weight, height and waist circumference), body composition (skinfold thickness and subscapular), biochemical (fasting glucose - FPG, postprandial glucose - GPP, glycated hemoglobin - A1C, total cholesterol - TC, triglycerides - TG, high density lipoprotein - HDL-c and low density lipoprotein - LDL-c) and, fortnightly, 24-hour recalls. Statistical analysis was performed using the statistical package SPSS version 18.0. For categorical variables used the chi-square and Fisher exact test. Shapiro-Wilk test to assess the normality of continuous variables, paired t test or Wilcoxon test for intragroup analysis, and Student's t test or Mann-Whitney test for intergroup analysis. The significance level was 5%. Results: The CG increased A1C (p=0.024) and both groups decreased energy intake (CG: p=0.005; IG: p=0.002). IG decreased A1C (p=0.002), but increased the CT (p=0.009) and LDL-c (p=0.012). This group also increased the caloric intake of carbohydrates (p=0.005) and decreased caloric intake of fat (p=0.002). There were a decreased in FPG and A1C (p=0.033 and p<0.001, respectively) in IG and increased CT and LDL-c (p=0.004 and p=0.019, respectively). The mean capillary glucose pre-and post-prandial were not affected between groups (p>0.005), although the oscillation glucose was lower in IG. Conclusion: Carbohydrate counting resulted in improved glycemic control and glucose concentrations more constant. However, this practice was associated with increased CT and LDL-c. Patients who have applied this strategy increased the caloric intake of carbohydrates and decreased consumption of fat.Item Eficácia da implantação das boas práticas de preparação na qualidade microbiológica de dietas enterais de um hospital público(Universidade Federal de Goiás, 2011-03-25) ALBUQUERQUE, Marinez Ferreira Barbosa; CAMPOS, Maria Raquel Hidalgo; http://lattes.cnpq.br/9910969694141110Poor hygienic sanitary conditions in the processing of enteral diets constitutes in risks of microbial contamination, and may involve complications in patients with enteral nutrition, ranging from infections digestive up to systemic infections. For this reason is important its microbiological control, whereas individuals to whom they are intended, are more susceptible to infections. Thus, this study aimed to compare the hygienic conditions of enteral diets before and after the implementation of Good Manufacturing Practices in a public hospital in Brazil. The study was developed in the Enteral Diet Unit of the Goiânia Emergency Hospital in three stages. In stage 1 before the implantation of good practices, carried out between November and December of 2008, was diagnosed the preparation conditions of the enteral diets by systematic observation of the conduct adopted by food handlers. Was applied the check list proposed by Resolution RDC nº 63 of Agência Nacional de Vigilância Sanitária/Brazil and realized microbiological analyzes of 40 samples of each element investigated: filtered water, powdered diet, reconstituted enteral diet and food handler s hand and nasal cavity culture. The good practices were implemented in phase 2, between January and June 2009, by educational training through the Maguerez Arch technical, development of Good Manufacturing Practices Handbook and by structural changes in the Enteral Diet Unit. In stage 3, between September and November 2009, was applied again the check list and repeated all microbiological analyzes carried out in the first phase, in addition the reconstituted enteral diets were analyzed at ambient temperature at Time 0 (preparation) and 1, 2, 3, and 4 hours after preparation. Both in stage 1 and 3, viable aerobic mesophilic microorganisms, total coliforms, Escherichia coli, coagulase-positive staphylococci, Staphylococcus aureus, Salmonella sp., and Pseudomonas aeruginosa were investigated. The results were compared with standards established by the Brazilian Sanitary Surveillance Legislation. Were used the software SPSS version 17.0 and STATA version 8.0 for statistical analysis and applied the McNemar test and Fisher exact test. The implementation of good practices significantly increased conformity to checklist items from 50.8% to 78.8% (p<0.001) and reduced the prevalence of contamination in the reconstituted enteral diet from 40.0% to 15.0% (p=0.031). The enteral diet could be considered safe after up to four hours at room temperature because asceptic preparation techniques were strictly followed. A significant reduction in the presence of Escherichia coli in the food handler s nasal cavity was detected (p=0.021). Conclusion: The implementation of good manufacturing practices contributed to the improvement of the enteral diet s hygienic sanitary conditions. Continued training is recommended to improve the food handlers competenciesItem Mulheres com lesões precursoras ou invasivas do colo de útero: a realidade do atendimento no Sistema Único de Saúde(Universidade Federal de Goiás, 2011-08-17) ALBUQUERQUE, Zair Benedita Pinheiro de; SOUZA, Adenicia Custodia Silva e; http://lattes.cnpq.br/5966034868102264; AMARAL, Rita Goreti; http://lattes.cnpq.br/3665611660713029OBJECTIVE: To investigate whether women with altered cervical cytopathological outcomes have been referred to Medium Complexity Units (MCU) as in accordance with the Brazilian Ministry of Health guidelines, as well analyze the perception of these womens about the attention received and the psychologic aspects that involved the diagnosis and treatment. METHODS: Descriptive, exploratory, quantitative and qualitative study based on the cytopathological outcomes of the BHS users carried out in Basic Health Assistance Units (BHAU) referred to Medium Complex Units (MCU) in the municipality of Goiânia, State of Goiás, 2005/2006. We assessed 1.109 records regarding the Brazilian Ministry of Health/the National Institute of Cancer guidelines as established by the Brazilian Nomenclature for Cervical Outcomes and Preconized Clinical Practice. Data was analyzed and processed by using Epi-info 3.3.2, 2006 and Microsoft Excel 2007. Variables were assessed descriptively, through calculus of relative and absolute frequency. For qualitative analysis, the interview method were used containing the subject caracterization and two guiding questions: one with negative polarity and other with positive polarity. RESULTS: From the total number of referrals, 79% were not in accordance with the Brazilian Ministry of Health guidelines which originated a great number of unnecessary procedures. The qualitive analysis explicitated fails on the professional attendance and in this attendance flow regarding to comunication about the actions relatives to treatment, services humanization and no observations of the established flow. The psycosocial aspects demonstrated that women didn t receive the necessary psicological attention to minorate the feelings of pain, despair, shame and, most of all, fear of death and mutilations. CONCLUSIONS: We observed inadequate referrals to the MCUs, which demanded a big number of unnecessary procedures. In women s perception, the attendence was permeated by fails in the reception, in communication, professional assistence, lack of knowledge about the attendence flow. The psycosocial aspects demand treatment integrality with multiprofessional teams working according to a biopsycosocial model.Item Investigação da acalásia do esfíncter anal interno por meio da eletromanometria de pacientes chagásicos obstipados com e sem megacolo (Goiânia-Goiás-Brasil)(Universidade Federal de Goiás, 2012-02-02) ALMEIDA, Arminda Caetano de; MOREIRA, Marise Amaral Rebouças; http://lattes.cnpq.br/6390358577348486Chagas disease remains as an important public health challenge in South America. The Chagas colopathy is considered the second clinical digestive manifestation most common of the disease and constipation chronic, its main symptom. The general objective was to investigate the presence of achalasia, through electromanometry of the internal anal sphincter, in constipated chagasic patients with and without megacolon. This study evaluated clinical and electromanometry parameters of 64 patients with symptoms of constipation, attended on the service of coloproctologya on a university hospital in Brazil, central region. The achalasia was present in 91.3% (IC95% 74.13 to 98.52) of patients with megacolon and/or megarecto (Group 1), in 47.29% (IC95% 27.29 to 68.57) without megacolon and/or megarecto (Group2), and was not present in patients of the control group (Group 3). The rectal capacity was 309.1, 159.2 and 150.1 ml in the groups 1, 2 and 3 respectively. In conclusion the electromanometry detects achalasia of the internal anal sphincter in almost totality of patients with megacolon and/or megarecto. The megacolon presence in constipated patients with Chagas Disease alert to the possibility of occurrence of achalasia on the internal anal sphincter. In chronically constipated patients with positive serology for Chagas Disease, without megacolon the a finding of absence of the recto anal inhibitory reflex, by electromanometry, can definitively prove the Chagas colopathy, while the presence of reflection departs, at the time, this diagnosis, should these patients be followed and treated like other patients with constipation due to other causes The comparison of clinical manifestations in the three groups not evidenced differences that could distinguish patients with Chagas colopathy those with functional constipation, reaffirming the importance of holding the electromanometry in Chagasic and constipated patients.Item Desenvolvimento farmacotécnico e analítico de comprimidos revestidos de montelucaste: equivalência farmacêutica e bioequivalência(Universidade Federal de Goiás, 2011-03-18) ALVES, Carina Pimentel Itapema; LIMA, Eliana Martins; http://lattes.cnpq.br/7248774319455970Montelukast is a potent reversible selective inhibitor of cysteinilleukotrien- 1 receptor, avoiding that these mediators promote the asthmatic response. Its commercialization in Brazil, as a terminated product, is protected by patent up to 2010. Once the active ingredient Montelukast is recent in the pharmaceutical market and there is no methodology description in official compendiums capable to assure the quality of new formulations, the objective of this paper was the pharmaceutics of montelukast film coated tablets, the development and the validation of analytical and bioanalytical methodologies foreseeing the pharmaceutical equivalence and bioequivalence with the reference medication of the market. With this purpose, some physicalchemical parameters were characterized, assay and dissolution methodologies were developed and validated per high performance liquid chromatography with ultraviolet detection (HPLC-UV) for the quantification of montelukast present in 10.0mg film coated tablets. The quantification of montelukast sodium in human plasma was performed using Loratadine as internal standard and high performance liquid chromatography attached to mass detector (HPLC - MS / MS). The active ingredient was extracted from the human plasma using precipitation extraction. The results found for the parameters of specificity, linearity, accuracy, precision, quantification and detection limits and stability in the methodologies validation confirm they were adequate for the objective proposed. The analytical methodologies developed and validated were applied in the pharmaceutics of the tablets for the determination of the formulation similar to the market reference medication Singulair®. This formulation was submitted to stability assays to assure its quality and to allow the performance of pharmaceutical equivalence and bioequivalence with the purpose of registering as a generic medication.Item Lesões Traumáticas Dento-Alveolares em Dentes Decíduos: Estudo Retrospectivo.(Universidade Federal de Goiás, 2010-05-14) AMORIM, Lilian de Fátima Guedes de; COSTA, Luciane Ribeiro de Rezende Sucasas da; http://lattes.cnpq.br/9906371509661305; ESTRELA, Carlos; http://lattes.cnpq.br/3611967334176683Aim: Determine the prevalence of dental injuries (TDI) in primary teeth and the influence of predisposing clinical factors on their occurrence and analyze the prevalence of developmental sequelae in permanent teeth and determine the association between these sequelae and age, gender, injury type, injury recurrence and sequelae in primary teeth, in children under 7 years old who sought treatment at a private pediatric dental clinic in Goiânia, Goiás, over a period of 15 years. Methodology: A retrospective study which analyzed 2725 dental records. Three hundred and eight dental records with 412 traumatized primary teeth were selected. This constituted the sample used to determine the prevalence of injuries in primary teeth and their association with predisposing clinical factors (Article 1); of these, 241 primary teeth (148 dental records) were followed up until the eruption of the permanent successor teeth. This was the sample for the study of sequelae in primary and permanent teeth (Article 2). All the data were statistically analyzed using the frequency distribution, chi-square test and logistic regression analysis. The level of significance was 5%. Results: The prevalence of dental injuries was 11.3%, with the greatest frequency in the 13-36 month age group. There was no statistical difference between genders. The most frequently affected teeth were the maxillary central incisors (83.3%). The main location of inuries was the home (43.5%), with falls the most frequent cause. The prevalence of dental TDI was similar in all months of the year. The most common type of TDI was subluxation (35.1%). Clinical factors overjet > 3 mm and negative overbite showed a significant difference between the trauma and no-trauma groups. In 46.5% of the cases, treatment was sought in the first 24 hours after the trauma. The most prevalent type of treatment was follow-up (51.0%). Color alteration of crown (26.0%) was the most frequent sequelae for primary teeth. The sequelae found in permanent teeth were enamel discoloration and/or hypoplasia (74.1%) and eruption disorder (25.9%). No significant relation was found between sequelae in permanent teeth and sequelae in primary teeth, type of trauma, gender or TDI recurrence. The only statistical difference was found in relation to the child s age at the moment of trauma. Conclusion: Immediate treatment of the child with a TDI, associated with the efficient diagnosis and long-term follow-up are decisive for the success of treatment. New research to help establish an effective protocol for the treatment of TDIs in primary teeth and the implementation of strategies that prepare professionals to treat TDIs and to educate the public about prevention and treatment of these lesions is necessary..Item BEVACIZUMABE INTRA-VÍTREO: ANÁLISE DA TOXICIDADE RETINIANA APÓS 3 MESES EM OLHOS DE COELHOS NÃO ALBINOS(Universidade Federal de Goiás, 2009-06-19) ARRAES, João Carlos Diniz; ÁVILA, Marcos Pereira de; http://lattes.cnpq.br/3335187297522447Antiangiogenesis therapy has become a first-line treatment for neovascular age-related macular degeneration (AMD). Bevacizumab has proven to be efficient and cost effective, however its use in AMD is still off-label. PURPOSES: Evaluating the histological toxicity of bevacizumab on the neurosensorial retina (NSR) and the retinal pigmented epithelium (RPE) in pigmented rabbit eyes; evaluating if a fast increase in vitreous volume after a 0.1 ml balanced saline solution (BSS) intravitreal injection (IVI) in a rabbit eye will lead to histological damages in the NSR and RPE; and evaluating postoperative clinical complications after an IVI in rabbits eyes. METHODS: Eighteen pigmented rabbits (36 eyes) were divided into 4 groups a Control Group (3 rabbits - 6 eyes), which did not receive any IVI; the rabbits were sacrificed at the beginning of the study. Thirty eyes of the fifteen remaining rabbits were distributed to three groups: a sham group (S), that received a 0.1 ml balanced saline solution (BSS) IVI (ten eyes); group 1, that received a 1.25 mg (0.1 ml) bevacizumab IVI (ten eyes); and group 2, that received a 2.5 mg (0.1 ml) bevacizumab IVI (ten eyes). Postoperative clinical evaluation included inspection of the anterior segment and indirect binocular ophthalmoscopy. The rabbits were sacrificed 90 days after the procedure and both eyes of all the rabbits were enucleated. Histological examination of the NSR and RPE were performed and their morphological features and layer thickness were analyzed. RESULTS: No significant postoperative clinical complications were observed either in the neurossensorial retina or in the RPE. Histological morphology and thickness of the NSR and RPE layers did not differ significantly between BBS-injected eyes and bevacizumab-injected eyes. CONCLUSIONS: A rapid increase in vitreous volume, after 0.1 ml BSS IVI did not lead to any histological damage in the NSR and RPE in rabbit eyes. After a 90-day follow-up period, a single Bevacizumab 1.25 and 2.5 mg intravitreal injection did not lead any toxic damage in the NSR and RPE. No important postoperative complications in pigmented rabbit eyes were observed and it appears to be a safe procedure for the treatment of retinal neovascular diseasesItem Efeitos de um programa individualizado e supervisionado de exercícios para os músculos do assoalho pélvico em multíparas de parto vaginal(Universidade Federal de Goiás, 2012-04-16) ASSIS, Thaís Rocha; AMARAL, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579This study consists of two scientific papers. The first aimed at investigating the effects of an individualized and supervised exercise program to strengthen pelvic floor muscles (PFM) in the postpartum period of multiparous women, and verify the correlation between two methods used to assess muscle strength. The second paper aimed at verifying the perception that puerperal women have regarding the alterations to their vaginal area and sex life after childbirth and after a PFM exercise program. To achieve these goals, an open clinical trial was performed on the first study, while the second conducted an exploratory and descriptive study. The final sample consisted of 23 puerperal women divided into two groups: intervention group (IG, n=11) and control group (CG, n=12). In IG, the puerperal women participated in an eight-week PFM exercise program, twice a week. In CG, the puerperal women did not receive any recommendations regarding exercises. PFM strength was assessed by digital vaginal palpation using the modified Oxford Scale and perineometer. The statistical analysis of the first article was performed using the following tests: Fisher s Exact Test, Chi-squared Test, Student s t-test, Kolmogorov Smirnov test for the two samples, and Pearson s Correlation Coefficient. Significance was defined as p < 0.05. On the second paper, categories were established and content analysis was performed. The participants mean age in IG was 24 ± 4.56 years, and 25.33 ± 4.03 years in CG (p=0.465). By completing the PFM exercise program, a significant difference was observed between the groups in the two muscle strength assessments (p0.001). The two methods used to assess muscular strength showed significant correlation in both assessments (1st assessment: r = 0.889 with p <0.001; 2nd assessment: r = 0.925 with p <0.001). In terms of the participants perception regarding any vaginal alteration in the late postpartum period, the most frequent reports in both groups were those related to the category perception of low vaginal tonus . Fourteen weeks into the postpartum period, at the end of the exercise program, the participants in IG presented more reports in the category perception of increased vaginal tonus and greater control over the PFM and those in the CG, in the category feels that the vagina is back in the same condition as before pregnancy . Finally, the exercise program resulted in a significant increase in PFM strength in puerperal women and showed positive effects on the perineal area and in the sex life of the participants. Good correlation was observed between digital vaginal palpation and perineometer, which indicates that vaginal palpation can be used in clinical practice, considering it is an inexpensive method that demonstrated significant correlation with an objective method, i.e. perineometer.Item Prevalência de problemas de saúde mental em populações de crianças e adolescentes indígenas Karajá da Amazônia brasileira(Universidade Federal de Goiás, 2012-03-14) AZEVÊDO, Paulo Verlaine Borges e; CAIXETA, Leonardo Ferreira; http://lattes.cnpq.br/9536747113677509Objective: To determine the prevalence of mental disorders in children and adolescents from an indigenous population living in isolated tribes in the Brazilian Amazon. Methods: This is an analytical prevalence study in a sample of 192 indigenous children and adolescents from Karajá ethnicity, aged between 7 and 14 years old. The prevalence were determined using the syndrome scales of mental health problems according to the ASEBA questionnaires. The Child Behavior Checklist 6-18 (CBCL) and the Teacher Report Form 6-18 (TRF) were used for the screening of these problems. The difference among the prevalence found in the two questionnaires as well as the risk association between gender and schooling and mental health problems were evaluated. Results: A total prevalence of problems of 34.38% with the CBCL and of 23.44% with the TRF was found (p < 0.00). There was an association between the occurrence of these problems in the subjects attending the second phase of fundamental school (6th to 9th year of formal education). Conclusion: The prevalence of mental health problems found was high when compared to studies with other cultures around the world. It was observed that even in human populations who preserve the primordial cultural aspects of their ancestors who lived 10.000 years ago, psychiatric problems exist and have clinical presentations that are similar to those found in modern civilized societies, in which the cultural context may influence the manifestations of such problems.Item Composição corporal e antropometria de idosos:concordância entre métodos, desenvolvimento e validação de equações preditivas e pontos de corte(Universidade Federal de Goiás, 2011-05-09) BARBOSA, Larissa Silva; SILVEIRA, Erika Aparecida da; http://lattes.cnpq.br/3801865783333828The aim of this study was to assess body composition and anthropometry of the elderly with regard to agreement between methods, development and validation of predictive equations and cutoffs. We evaluated 132 elderly patients (52 men and 80 women) aged between 60 and 91 years, users of primary health care, not institutionalized and drawn at random in proportion to the nine health districts of Goiânia, GO. For collection of anthropometric measurements, bioelectrical impedance (BIA) and dual energy x-ray absorptiometry (DEXA), standardized procedures were used by trained examiners and equipment was calibrated regularly. Analyses were performed using STATA/SE. Descriptive analysis, tests for comparison of means, equation validation according to criteria suggested by Lohman, Bland-Altman and Lin graphic analysis and ROC (receiver operator characteristic curve) analysis were carried out. The project was approved by the Ethics Committee of the Federal University of Goias. The Durnin and Womersley equation showed the highest concordance correlation coefficient (CCC = 0.846) and the lowest mean differences (MD = - 2.335) for males. The equations of Lean et al. (for men) and Deurenberg et al. (for women) showed the highest correlation with and lowest mean differences from DEXA. Equations were proposed to estimate body fat percentage (BF%): (males: BF% = - 16.868 + 0.571TSF + 0.409WC and females: BF% = 8.634 + 0.601BMI + 0.321SISF + 0.234SSSF + 0.398TSF 0.467BSF). In both sexes, the equations are similar to DEXA in estimating BF% with high precision and accuracy. In males, the proposed body mass index (BMI) cutoff point was ≥ 25 kg/m2; the waist circumference (WC) cutoff point was ≥ 98.9 cm. In women, the BMI and WC values with the most sensitivity, specificity and accuracy were ≥ 26.6 kg/m2 and ≥ 90.5 cm. Since the currently available equations for predicting body composition of elderly have certain limitations, these newly developed and validated equations for the two sexes can be recommended for wide use. Accurate BMI and WC cutoff points for predicting BF% in older adults were also identified.Item Composição Mineral e Capacidade Antioxidante de Citros Cultivados em Goiás(Universidade Federal de Goiás, 2011-04-04) BARROS, Helena Rudge de Moraes; FERREIRA, Tânia Aparecida Pinto de Castro; http://lattes.cnpq.br/0312123979235562Fruits provide not only essential nutrients for the functioning of human life systems; but also bioactive compounds that reduce the risk of developing chronic diseases. This protective effect has been attributed to antioxidant properties performed by bioactive compounds, which citrus fruits are important sources, such as ascorbic acid, phenolic compounds and also of some minerals. Brazil is one of the major citrus producers, and about 90% of this production is destined for the juice production, with a large production of waste that could be reused. Thus, aim of this study was to evaluate and compare the mineral composition, content of total phenolics, ascorbic acid content and antioxidant capacity of skin and pulp of five citrus varieties cultivated in Goiás. The results were subjected to analysis of variance and Tukey test (p <0.05) for comparison of means. In general, the peels showed higher levels of all compounds tested, with the exception of ascorbic acid in the orange pera pulp had the highest content of acid lime peel and Tahiti had the lowest content. Citrus showed high levels of potassium, calcium and magnesium, and the peels considered "sources" of these minerals. Concentrations of trace elements also were found, cofactors of antioxidant enzymes. The phenolic compounds of peels were from 2.5 to 4 times higher than the pulps, especially the orange peel lime. As for antioxidant capacity, tangerine peel Ponkã showed the best results. Citrus fruits are from a variety of bioactive compounds and the shells can be exploited to produce functional foods or replacing the use of synthetic antioxidants.Item Estudo comparativo randomizado do tratamento da bexiga hiperativa com eletroestimulação vaginal e eletroestimulação transcutânea do nervo tibial posterior(PTNS)(Universidade Federal de Goiás, 2012-02-15) BERQUÓ, Marcela Souza; AMARAL, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579INTRODUCTION: The overactive bladder syndrome (OAB) is a lower urinary tract pathology that negatively affects the quality of life (QOL) of women whose main symptom is your definition for urinary urgency, with or without incontinence usually accompanied by urinary frequency and nocturia in the absence of metabolic, infectious or local. The diagnosis of BH is defined from the clinical symptoms, but the voiding diary and urodynamic studies are good tools for objective evaluation of this pathology. There are several forms of treatment for OAB, are the main pharmacological and physical therapy, physical therapy has been being considered an important option in a clinical setting. OBJECTIVES: to do a systematic review article about physical therapy in the treatment of female miccional urgency, to evaluate and compare the effects, discomfort and improvement in quality of life (QOL) of vaginal electrostimulation and percutaneous tibial nerve stimulation (PTNS) in women with overactive bladder. METHODS: We conducted a comparative, prospective, randomized trial of physiotherapy in the sector of the Hospital Materno Infantil (HMI) in Goiânia-GO, from march 2010 to august 2011. We randomized 40 women with urodynamic diagnosis of detrusor overactivity, mixed incontinence with predominant symptoms of overactive bladder or urinary urgency only in two groups: vaginal electrical stimulation (n=20) and PTNS (n=20), being held 10 sessions in each group. We used urodynamic studies, voiding diary and QoL questionnaire of King's Health Questionnaire (KHQ) before and after the two procedures, and then visual analog scale. Statistical analysis used: Fisher exact tests, chi quadratic, U Mann Whitney and Wilcoxon tests with a significance level of 0.05. RESULTS: In voiding diary was a reduction in urinary frequency, urge incontinence, nocturia and urgency in both groups. The urgency was present in all women and disappeared in 90% in the PTNS group (p<0.001) and 80% in vaginal electrical stimulation (p<0.001). According to urodynamic evaluation, the group of vaginal electrostimulation showed disappearance of detrusor overactivity in 60% (p=0.005) and PTNS in 75% (p= 0.002). The urodynamics showed significant differences in some parameters analyzed within each specific group and to compare the two groups was not observed differences. The scale and the KHQ domains of the two procedures had similar results as physical therapy to improve QOL, but no significant difference between them. In relation to the discomfort of procedures, PTNS in 80% of women reported no discomfort and 80% reported vaginal electrostimulation mild to moderate discomfort (p<0.001). CONCLUSION: There was no significant difference in the effects and QOL between the vaginal electrical stimulation and PTNS. The PTNS promoted less discomfort for women.Item Estudo da Relação entre Hiperatividade dos Músculos Esfenomandibulares e dor ocular(Universidade Federal de Goiás, 2010-07-13) BORGES, Raulino Naves; ÁVILA, Marcos; http://lattes.cnpq.br/3335187297522447study was based on the hypothesis that a TMD can be the etiological factor in ocular pain and to test it the authors performed a clinical evaluation in TMD patients presenting with sphenomandibular muscle hyperactivity. The hypothesis is based on the fact that the muscle originates in the lateral aspect of the orbit, with a point of insertion in the mandible. It is an observational and descriptive study, characterized by: 1) an anatomical investigation performed in cadavers and 2) a clinical interpretation of the physiological relationship between sphenomandibular muscle functions and symptoms involving temporomandibular disorders presenting with ocular pain. Ten anatomical specimens (five cadavers) from the Anatomy Department of the School of Medicine of the Catholic University of Goiás were examined. One hundred three patients with temporomandibular disorders (TMD) were treated and followed in the Outpatient Clinic of the School of Dentistry of the Federal University of Goiás for the purpose of studying the interrelationship between cervical and craniofacial pain symptoms and craniomandibular disorders. The work was carried out in the Outpatient Clinic of the School of Dentistry of the Federal University of Goiás, between April 2006 and December 2008. Inclusion criteria, used to form Group I, totaling 58 patients, included temporomandibular disorders, referred ocular pain and sphenomandibular muscle hyperactivity. Group II comprised 45 patients who did not present with sphenomandibular muscle hyperactivity. All the patients received treatment for Temporomandibular Disorder (Groups I and II) and were followed for two years, with biannual evaluation visits. Response to treatment was evaluated by means of an opinion-based questionnaire that served to stratify the level of ocular pain, which was reported as eliminated in 46 of the 58 patients in Group I (79.3%) and in eight Group II patients (17.8%). This evaluation has made it possible for the authors to affirm that the sphenomandibular muscle is independent from the temporal muscle and is closely related to the orbit; the clinical examinations conducted along the study enabled the evaluation of sphenomandibular muscle hyperactivity in temporomandibular disorder episodes; and this hyperactivity is significantly associated to the presence of referred ocular pain.Item Adesão de pessoas adoecidas de AIDS (Síndrome da Imunodeficiência Adquirida) à terapia antiretroviral: estudo clínico e laboratorial à partir da orientação de Enfermagem(Universidade Federal de Goiás, 2011-02-21) BRASILEIRO, Marislei de Sousa Espíndula; CUNHA, Luiz Carlos da; http://lattes.cnpq.br/6349547031976679Adherence to antiretroviral therapy reduces the risk of treatment failure, toxicity and resistance, so the therapeutic monitoring is necessary in the treatment of infection by human immunodeficiency virus. The aim of this study was to determine, through clinical and laboratory studies, the compliance of individuals sickened by HIV / AIDS with antiretroviral therapy before and after three nursing interventions. The study design was analytical, descriptive, prospective and quantitative, using data from medical records, interviews and blood sampling for plasma levels of efavirenz by HPLC analysis, including subjects with a diagnosis of HIV / AIDS, attended at the Hospital for Diseases Tropical Goiânia - Goiás and treated with zidovudine/ lamivudine and efavirenz. The results of analysis of data from 15 subjects indicate a socio-demographic profile, predominantly male, young, heterosexual. After nursing intervention, there was a change in 48% of the diagnoses. We also noticed a positive change in the rates of CD4, corresponding to 14%. As viral count, an increase of subjects with undetectable loads of 1 st to 2 nd nursing intervention (20%, or 73.3% to 93.3%). Chromatographic analysis of plasma of the subjects indicated that 60% of them had adequate medication adherence, and 40% increased adhesion between the 1st and 2nd visits by nurses, 10% between the 1st and 3rd and 10% between the 2nd and 3rd queries. The factor that was associated with high concentration rate after adjustment in nursing diagnoses and prescriptions was having difficulty using the antiretroviral in the same time. It was also demonstrated significant difference between mean plasma concentrations of efavirenz from the 1st, 2nd and 3rd interventions. Considering the reference measurement of plasma concentrations of efavirenz, the method of accession had a sensitivity and specificity, with high proportion of agreement between the rate of CD4, nursing diagnosis and analysis of the plasma of subjects. Conclusions: the systematization of nursing care and determination of plasma concentrations should be incorporated into the routine outpatient care, for better monitoring of adherence to antiretroviral therapy of individuals sickened by HIV / AIDS.Item Aspectos Inflamatórios e Imunológicos de Pulpites Dentárias Humanas(Universidade Federal de Goiás, 2009-09-18) BRUNO, Kely Firmino; ESTRELA, Carlos; http://lattes.cnpq.br/3611967334176683Immune and inflammatory cells may contribute to host defense and microenvironmental changes during the pathogenesis of dental pulpitis. This study evaluated the microscopic characteristics and densities (per mm2) of tryptase+ mast cells, CD4+ T helper lymphocytes, CD45RO+ memory T lymphocytes, foxp3+ T regulatory lymphocytes, CD20+ B lymphocytes, CD68+ macrophages, and CD31+ blood vessels in human dental pulpitis (n = 38). Methods: Tryptase, CD4, CD45RO, foxp3, CD20, CD68, and CD31 expressions were analyzed using immunohistochemistry; other microscopic features, such as intensity of inflammatory infiltrate and collagen deposition, were evaluated after staining with hematoxylin and eosin. Results: Two microscopic patterns of dental pulpitis were found: group 1 (G1) (n = 15) showed intense inflammatory infiltrate and mild collagen deposition; conversely, group 2 (G2) (n = 23) showed scarce inflammatory infiltrate and intense collagen deposition. The numbers of CD68+ and CD20+ cells and the density of blood vessels were higher in G1 than in G2. However, there were no differences in CD4+ and CD45RO+ cell densities between groups. When present, mast cells were equally distributed in G1 and G2, whereas foxp3+ cells were detected in 58.82% and 14.28% of the samples of G1 and G2. Conclusions: Immune and inflammatory cell infiltration have different patterns in human dental pulpitis, which might reflect distinct microscopic characteristics and particular local defense capabilities.Item Avaliação da implantação do currículo de Nutrição da Universidade Federal de Goiás na visão docente(Universidade Federal de Goiás, 2011-04-01) BUENO, Caroline Damásio; COSTA, Nilce Maria da Silva Campos; http://lattes.cnpq.br/6977373149115047The Federal University of Goiás estabilished in 2009 a new curriculum for nutrition graduation, supporte by the National Curriculum Guidelines for undergraduate courses in Nutrition and the Reorientation National Program in Health Professional Formation. Study conducted to objective was to identify the perceptions of nutritions professors of implantation the new curriculum, by means on qualitative approach. Data were collected from the interview semi-estructured with 12 professors and were analyzed from the thematic content analysis. The study revealed most professors did not clear knowledge of curriculum. The potentialities were: early insertion of students into scenarios for practical since their first year of graduation, active teaching-learning methodologies and insertion of contents on the work world. The limits were: change of students admitted in undergraduate course, inadequate infrastructure of institution education and health services, overload activities, commitment teaching and insecurity with curriculum reformation. Among the strategies of teaching and learning were cited the expository class and the dialogue-based lecture, the seminar, the text study and the problem-solving. The curriculum reform generated a change in strategy with the introduction of active teaching-learning methodologies and case study in a discipline to integrate the basic cycle-professional. Were considered fragilities, the lack pedagogical training of teachers and resistance from students and teachers of active teaching-learning methodologies. The study revealed that that curriculum reformulation has advanced attending to the curricular guidelines and principles for reorientation in health professional formation. Involves administrative, physical and human being factors. More discussion and reflection were indicates that become reality. The study reveal to the requirement for institutional development of teachers in teaching to improve teaching quality. Support to base, enhance and socialize experiences and stimulate news curriculum research.Item Alimentação Saudável na Escola: Uma Construção Coletiva?(Universidade Federal de Goiás, 2011-03-25) CAMOZZI, Aída Bruna Quilici; MENEZES, Ida Helena Carvalho Francescantonio; http://lattes.cnpq.br/8722459243487573; MONEGO, Estelamaris Tronco; http://lattes.cnpq.br/0917323812776538Changes in the contemporary eating pattern are closely related with the increase in the prevalence of chronic diseases, reason why national and international policies focus on this problem. School is taken as a priviledged space for health and healthy eating promotion, since as it should contribute to the development of a critical thinking, autonomous citizen, it should also favour the adoption of healthy lifestyles. However, there are little known initiatives with such purpose, so that lapses between legal dispositions and observed experience are identified. The objective of this study was to analyze healthy eating perception as well as healthy eating promotional acts carried in the school community, to describe facilitating and hindering factors in their implementation, and to comprehend how healthy eating promotion policies are executed in such social space. It is a descriptive-exploratory study with qualitative approach using focal groups, which interpretation was done according to the thematic content analysis. Research was carried in six elementary grade schools appointed by Goiânia's municipal education bureau, of which principals and coordinators comprised the management group, and pofessors, food manipulators and school council representatives comprised the doers group. Data analysis has evidenced a biologist view of healthy eating, as well as a welfare comprehension of the role of eating at school. Healthy eating promotion activities were limited to classroom approach by teachers and to dispersed activities aimed at increasing meals' acceptability. Were cited as healthy eating promotion facilitating factors the teachers' compromise and coordinators' involvement with the subject, the variety of food genres and hygienic preparation of school meals, the interface between health and education, and the role of students in retransmitting the knowledge to the family. Hindering factors were the limited availability of educational material, teachers' inadequate training for approaching the subject, lack of food manipulators' training, menu and infrastructure inadequacy, lousy parental interaction in the process and the conflict between healthy food and tasty food. Conclusion is that healthy eating promotion policies were not adequately inserted in the school environment, which imply the need of involving the whole school community in a collective pedagogical project that allows the transverse inclusion of the subject in the school curriculum. As such, it is suggested that teachers and food manipulators' training should contemplate active methodologies and their participation in the process, and that meals offered should be compatible with eating habits and with the sociocultural background of those involved. Finally, are accounted as pertinent the revaluation of proposed practices related to health pomotion projects,a greater intersectorial integration and the increasing of awareness of all involved, so to secure adequate and healthy eating at school.Item Avaliação de citocinas na secreção endocervico-vaginal de pacientes com vaginose bacteriana e papilomavírus humano(Universidade Federal de Goiás, 2011-03-09) CAMPOS, Ana Claudia Camargo; REIS, Cleomenes; http://lattes.cnpq.br/5103786277121402The vagina and the cervix are the first immune and physical line of defense against sexually transmitted pathogens. However infectious process in the vagina, caused by potentially pathogenic microorganism such as bacterial vaginosis (BV), are very often. This may be associated with a morbid entity as Human Papillomavirus (HPV). It was evaluated the association between the presence of BV and HPV in the lower female genital tract, identifying the clinical and lab aspects in women who received medical attention at emergency rooms in the city of Goiânia-GO and observed the production of cytokines in endocervical secretions in cases with VB associated with HPV. This study included 173 sexually active women, between 16 and 48 years old, divided into groups: control, with BV and with high and low risk of HPV. A survey was conducted to collect the intrinsic and extrinsic factors associated with the patients. Microbial cultures, vaginal pH, identification of high and low risk of HPV by PCR, and the concentration of cytokines were performed. The result of the research data was submitted to a statistical analysis, calculating the oods ratio, confidence intervals and p of 0,05. Forty seven cases of BV were diagnosed. Besides, the presence of a vaginal pH > 4.5, showed a result statistically significant for the presence of HPV, p = 0.001 was also observed. When analyzing the multivariate logistic regression, the independent risk factors for the presence of VB were: having more than one sexual partner in the last 5 years p<0,001 and have more than 3 sexual intercourses per week p=0,002. But in HPV infection the independent risk factors were: being married p=0,029 and pH ≤ 4.5 p<0,001 and in the case of high-risk HPV the only independent factor considered was the pH ≤ 4.5 p= 0,006. Relating HPV infections with high and low risk and the presence of VB with some immune factors by the strength of local cytokines, it was found that, IL-2 and IL-12 were significantly elevated in cases of BV and HPV. The IL-6 was high only for HPV, followed by IFN-gamma and IL-10 although the last two showed a trend towards statistical significance in HPV cases. It was concluded through the univariate analysis that the factors, having more than one sexual partner in the last 5 years, a failure in the use of condoms and the presence of leucorrhoea and dyspaurenia were related to the presence of BV and level of alkaline in the vagina which could possibly predispose to infections HPV, and the immune response Th1-type cytokines in vaginal secretions in the presence of BV and/or HPV may also be similar.Item Força de aperto de mão e estado nutricional de pacientes em hemodiálise(Universidade Federal de Goiás, 2012-03-02) CAMPOS, Marta Isabel Valente Augusto Moraes; PEREIRA, Edna Regina Silva; http://lattes.cnpq.br/4503589425013098; PEIXOTO, Maria do Rosário Gondim; http://lattes.cnpq.br/6813295858384008BACKGROUND: Protein energy wasting commonly occur in patients with chronic kidney disease. Changes in muscle function arise even before changes in anthropometric and biochemical parameters.Thus, a method for evaluating muscle function and strength becomes essential for these patients. OBJECTIVES: To evaluate the handgrip strength (HGS) and its association with nutritional status of patients with chronic kidney disease on hemodialysis. METHODS: A cross-sectional study conducted between May and July/2011. The sample included 90 patients, 48.8% male and 51.2% female. The HGS was performed three times with a hydraulic hand dynamometer (Takei) in the arm without fistula. For each patient were considered the best strength measure. Values lower than percentile 10 were considered as low HGS. The nutritional status diagnosis was given by Subjective Global Assessment (SGA). RESULTS: The average age was 52 ± 14.7 years. The hypertensive nephrosclerosis was the most frequent cause of chronic kidney disease (31.1%). The average HGS was among 32.0 ± 8.7kgf in men and 20.7 ± 6.1kgf in women (p<0.001). 11.3% of men and 21.7% of woman were classified as moderatey malnourished by SGA, 31.8% and 34.8% of men and women, respectively, were classified with low muscle function. Low HGS was associated with time on hemodialysis for men and showed good sensitivity (73.3%) and specificity (74.7%) for malnutrition diagnosis. In multiple logistic regression analysis, low-power handgrip strength prevalence was two times higher (PR =2.00, 95% CI: 1.19 to 3.34) for patients classified as moderate malnourished by SGA. CONCLUSION: This study showed high prevalence of low muscle function and good association between HGS and SGA in patients with chronic kidney disease on hemodialysis classified by dynamometry. It is suggested that HGS, an inexpensive and noninvasive measurement, can be used in clinical practice as a screening tool of nutritional status. It is sensitive for malnutrition diagnosis.Item Efeito da aplicação de cinesioterapia e eletroestimulação no trabalho de parto(Universidade Federal de Goiás, 2010-02-21) CANESIN, Kariny Fleury; AMARAL, Waldemar Naves do; http://lattes.cnpq.br/4092560599116579Aiming to evaluate the techniques described in the literature to decrease the time of labor birth and the application of techniques of exercise, massage and transcutaneous electrical nerve stimulation on the active phase of labor and intensity of pain in primiparas. The habit of women to keep moving during labor in an upright position (standing, sitting and / or walking) was a practice more common in some cultures. Historically, the postures and the vertical position change and ambulation have been reported to evolve as efficient dilation, relieve pain during contraction and facilitate the descent of the fetus through the birth canal. We conducted a randomized clinical trial, prospective which was attended by 60 women at the beginning of the active phase with 5 cm of cervical dilation, a public hospital in Goiania in the period July 2009 to July 2010. The women were divided into three groups: control (n = 20), exercise (n =20) and electrical stimulation (n = 20), and monitored during the active phase of labor. During this period, data were collected: Template for recording data (age, weight, height and maternal BMI, race, education), visual analog scale pain, and partograph (gestational age, duration of labor, weight and height of the newborn). In the study, comparing the group of exercise with electrical stimulation and control groups there was a significant difference in the time of labor (p = 0.003). However, in relation to pain intensity difference was not statistically significant (p> 0.05). It is concluded according to the literature there is no way to define a specific technique to encourage labor birth and techniques of exercise, electrical stimulation used in the active phase of labor, the motherspromote progression of labor, but not interfere in its intensity pain.